Synthesis and biological studies of new quinazolines with ether functions in position 2
Abstract
A series of new quinazolines linked to triazoles through an ether chain in position 2 has been designed and synthetized through a flexible route. Cytotoxicity assays on selected cancer cell lines and inhibition studies toward a panel of representative mammalian kinases have been performed on these molecules.
Domains
Medicinal Chemistry
Origin : Files produced by the author(s)
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