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The adiponectin agonist, AdipoRon, inhibits steroidogenesis and cell proliferation in human luteinized granulosa cells
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hal-03122484v1
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Two new cyclobutane dimers from Diospyros macrocarpa
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G. Herbette
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V. Monnier
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hal-01619687v1
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Rho-kinase/myosin light chain kinase pathway plays a key role in the impairment of bile canaliculi dynamics induced by cholestatic drugs
Ahmad Sharanek
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The rs3957357C>T SNP in GSTA1 Is Associated with a Higher Risk of Occurrence of Hepatocellular Carcinoma in European Individuals
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hal-01439220v1
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Investigation on the synthesis of new 3-[4-(arylalkoxy)phenylethyl]-2-thioxo-1,3-thiazolidin-4-ones and their biological evaluation against cancer cells
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Synthesis and biological evaluation of 3-amino-, 3-alkoxy- and 3-aryloxy-6-(hetero)arylpyridazines as potent antitumor agents
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Microwave synthesis of new 3-(3-aminopropyl)-5-arylidene-2-thioxo-1,3-thiazolidine-4-ones as potential Ser/Thr protein kinase inhibitors
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hal-01414293v1
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30th Franco-Belgian conference of pharmacochemistry
Charlotte Bouckaert
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Eric Goffin
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hal-02141338v1
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Characterization of Glyceollins as Novel Aryl Hydrocarbon Receptor Ligands and Their Role in Cell Migration
Thu Ha Pham
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Sylvain Lecomte
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hal-02499347v1
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Synthesis and toxicity evaluation of hydrophobic Ionic Liquids for Volatile Organic Compounds biodegradation in a two-phase partitioning bioreactor
Alfredo Santiago Rodriguez Castillo
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hal-01254799v1
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Microwave-assisted practical synthesis of 4-imino-3-phenyl-3,4-dihydro-1H-chromeno[2,3-d]pyrimidine-2(5H)-thione derivatives and exploration of their biological activities
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M. Fakhfakh
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S. Abid
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L. Paquin
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hal-01581215v1
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Reactivity Under Microwave Irradiation of 2-amino 4H-chromene-3-carbonitrile as tool for the construction of potential bioactive derivatives
Ali Bouattour
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Mehdi Fakhfakh
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Houcine Ammar
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Ludovic Paquin
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Jean-Pierre Bazureau
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3rd International Electronic Conference on Medicinal Chemistry, Nov 2022, Online, France
Conference papers
hal-03872422v1
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A practical multi-step synthesis of ethyl N-functionalized β-amino benzimidazole acrylate derivatives as promising cytotoxic agents
Christelle N'Ta Ambeu
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Rémy Le Guével
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Janat Akhanovna Mamyrbekova
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hal-01808102v1
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Synthetic Development of New 3-(4-Arylmethylamino)butyl-5-arylidene-rhodanines under Microwave Irradiation and Their Effects on Tumor Cell Lines and against Protein Kinases
Camille Déliko Dago
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Wacothon-Karime Coulibaly
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Yves-Alain Békro
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Janat Mamyrbékova
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hal-01187427v1
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Goodness-of-t test for multistable Lévy processes
Ronan Le Guével
Journal articles
hal-02275584v1
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Bisphenol A induces steatosis in HepaRG cells using a model of perinatal exposure
Simon Bucher
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Pégah Jalili
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Dounia Le Guillou
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Karine Rondel
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hal-01470709v1
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Discovery of Human-Similar Gene Fusions in Canine Cancers
Ronan Ulvé
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Mélanie Rault
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Mathieu Bahin
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Laetitia Lagoutte
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hal-01647128v1
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Structure Activity Relationship Studies around DB18, a Potent and Selective Inhibitor of CLK Kinases
Dabbugoddu Brahmaiah
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Anagani Kanaka Durga Bhavani
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Pasula Aparna
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Nangunoori Sampath Kumar
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Hélène Solhi
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hal-03828358v1
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Synthesis and biological studies of new piperidino-1,2,3-triazole hybrids with 3-aryl isoxazole side chains
Appala Venkata Ramana Murthy
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Vennu Narendar
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Pasula Aparna
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hal-03414697v1
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Design, biological evaluation and X-ray crystallography of nanomolar multifunctional ligands targeting simultaneously acetylcholinesterase and glycogen synthase kinase-3
Killian Oukoloff
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Nicolas Coquelle
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Manuela Bartolini
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Marina Naldi
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Rémy Le Guével
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hal-02055769v1
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Differential sensitivity of metabolically competent and non-competent HepaRG cells to apoptosis induced by diclofenac combined or not with TNF-alpha
Houssein Al-Attrache
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Audrey Burban
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Matthew Burbank
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Thomas Gicquel
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In-Depth Proteome Analysis Highlights HepaRG Cells as a Versatile Cell System Surrogate for Primary Human Hepatocytes
Georg Tascher
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Audrey Burban
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Sandrine Camus
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Marine Plumel
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Stéphanie Chanon
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hal-02050391v1
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An Efficient Solvent-Free Microwave-Assisted Synthesis of Cinnamamides by Amidation Reaction Using Phenylboronic Acid/Lewis Base Co-catalytic System
Khadidja Khaldoun
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Abdelmounaim Safer
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Salima Saidi-Besbes
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Bertrand Carboni
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Remy Le Guevel
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hal-02359980v1
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Synthesis and biological studies of new quinazolines with ether functions in position 2
D. Brahmaiah
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A.K.D. Bhavani
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P. Aparna
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N.S. Kumar
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H. Solhi
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hal-02161844v1
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Mechanisms of action and structure-activity relationships of cytotoxic flavokawain derivatives
Charlotte Thieury
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Nicolas Lebouvier
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Rémy Le Guével
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Yann Barguil
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Gaëtan Herbette
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hal-01485126v1
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Novel Tetrahydropyrido[1,2- a ]isoindolone Derivatives (Valmerins): Potent Cyclin-Dependent Kinase/Glycogen Synthase Kinase 3 Inhibitors with Antiproliferative Activities and Antitumor Effects in Human Tumor Xenografts
Rajâa Boulahjar
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Aziz Ouach
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Chiurato Matteo
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Stéphane Bourg
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Myriam Ravache
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hal-02904751v1
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Novel optimization of valmerins (tetrahydropyrido[1,2-a]isoindolones) as potent dual CDK5/GSK3 inhibitors
Aziz Ouach
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Rajâa Boulahjar
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Christine Vala
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Stéphane Bourg
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Pascal Bonnet
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hal-01295635v1
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At the crossroads of fertility and metabolism
Pascal Froment
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Ingrid Plotton
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Cecilia Giulivi
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Stéphane Fabre
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Rita Khoueiry
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hal-03658093v1
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De novo HAPLN1 expression hallmarks Wnt-induced stem cell and fibrogenic networks leading to aggressive human hepatocellular carcinomas.
Sihem Mebarki
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Romain Désert
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Laurent Sulpice
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Marie Sicard
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Mireille Desille
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inserm-01335675v1
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Design and Microwave Synthesis of New (5Z) 5-Arylidene-2-thioxo-1,3-thiazolinidin-4-one and (5Z) 2-Amino-5-arylidene-1,3-thiazol-4(5H)-one as New Inhibitors of Protein Kinase DYRK1A
Khadidja Bourahla
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Solène Guihéneuf
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Emmanuelle Limanton
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Ludovic Paquin
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Rémy Le Guével
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hal-03467664v1
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