Article Dans Une Revue European Journal of Organic Chemistry Année : 2024

One-Pot Double Cyclizations Involving an Aza-Prins Process

Résumé

Piperidine derivatives are highly abundant in natural products and pharmaceutically relevant compounds. Aza-Prins cyclization has emerged as a step-atom-economical and stereoselective method for the preparation of such azacycles. The possibility of coupling aza-Prins process with the formation of a second cycle in a one-pot manner is even more powerful and makes the object of this review. Cascade/domino/tandem bis-cyclizations involving an aza-Prins process, for the rapid construction of complex small molecules, are discussed in detail.

Scheme 7. Tandem cyclisation towards azasteroids.

Domaines

Chimie
Fichier principal
Vignette du fichier
Manuscript.pdf (1.72 Mo) Télécharger le fichier
Origine Fichiers produits par l'(les) auteur(s)

Dates et versions

hal-04810806 , version 1 (29-11-2024)

Identifiants

  • HAL Id : hal-04810806 , version 1

Citer

Nicolas Gouault, Maxence Roydor, Jacques Renault, Swarnayu Banik, B V Subba Reddy, et al.. One-Pot Double Cyclizations Involving an Aza-Prins Process. European Journal of Organic Chemistry, 2024. ⟨hal-04810806⟩
6 Consultations
4 Téléchargements

Partager

More