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Protolichesterinic acid derivatives: α-methylene-γ-lactones as potent dual activators of PPARγ and Nrf2 transcriptional factors.
Anne-Cécile Le Lamer
,
Hélène Authier
,
Isabelle Rouaud
,
Agnès Coste
,
Joël Boustie
et al.
Journal articles
hal-01114513v1
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Combined approaches for drug design points the way to novel proline racemase inhibitor candidates to fight Chagas' disease.
Armand Berneman
,
Lory Montout
,
Sophie Goyard
,
Nathalie Chamond
,
Alain Cosson
et al.
Journal articles
hal-00833388v1
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Analogues de mycosporines en tant que photoprotecteurs.
Sophie Tomasi
,
Nicolas Gouault
,
Karine Costuas
,
Khan Hung Nguyen
France, N° de brevet: Composés photoprotecteurs (V/Réf. DI : 1155_UR1_B - N/Réf. FR 13 53106 CEB). 2013
Patents
hal-00872735v1
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Gold-mediated synthesis and functionalization of chiral halopyridones.
Khanh Hung Nguyen
,
Sophie Tomasi
,
Myriam Le Roch
,
Loïc Toupet
,
Jacques Renault
et al.
Journal articles
hal-00866844v1
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Structural and molecular bases to IRE1 activity modulation
Timothy Langlais
,
Diana Pelizzari-Raymundo
,
Sayyed Jalil Mahdizadeh
,
Nicolas Gouault
,
François Carreaux
et al.
Journal articles
hal-03331317v1
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Synthesis of New gamma-Lactams with gem-Difluorinated Side Chains
Ali Soulieman
,
Nicolas Gouault
,
Thierry Roisnel
,
Frédéric Justaud
,
Joël Boustie
et al.
Journal articles
hal-02438548v1
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Integrating targeted gene expression and a skin model system to identify functional inhibitors of the UV activated p38 MAP kinase
Amaal Abrahams
,
Nicolas Mouchet
,
Nicolas Gouault
,
Françoise Lohézic-Le Dévéhat
,
Myriam Le Roch
et al.
Journal articles
hal-01439371v1
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Synthesis of novel kavain-like derivatives and evaluation of their cytotoxic activity
Patricia de A. Amaral
,
Julien Petrignet
,
Nicolas Gouault
,
Taciane Agustini
,
Françoise Lohézic-Le Dévéhat
et al.
Journal articles
hal-01470075v1
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Synthesis of Novel Cyclic Nitrones withgem-Difluoroalkyl Side Chains Through Cascade Reactions
Ali Soulieman
,
Rima Ibrahim
,
Zeinab Barakat
,
Nicolas Gouault
,
Thierry Roisnel
et al.
Journal articles
hal-02957740v1
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From Aspartic Acid to Dihydropyridone-2-carboxylates: Access to Enantiopure 6-Substituted 4-Oxo- and 4-Hydroxypipecolic Acid Derivatives
Huy-Dinh Vu
,
Jacques Renault
,
Loïc Toupet
,
Philippe Uriac
,
Nicolas Gouault
et al.
Journal articles
istex
hal-00872912v1
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Enantiospecific synthesis of pyridinones as versatile intermediates toward asymmetric piperidines.
Nicolas Gouault
,
Myriam Le Roch
,
Adèle Cheignon
,
Philippe Uriac
,
Michèle David
et al.
Journal articles
hal-00843472v1
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Lichen butyrolactone derivatives disrupt oral bacterial membrane
Alaa Sweidan
,
Imen Smida
,
Marylene Chollet-Krugler
,
Aurélie Sauvager
,
Julien Vallet
et al.
Journal articles
hal-02280840v1
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Prodrugs as new therapies against Chagas disease: In vivo synergy between Trypanosoma cruzi proline racemase inhibitors and benznidazole
Guilherme Dias de Melo
,
Nicolas Coatnoan
,
Nicolas Gouault
,
Jean-François Cupif
,
Jacques Renault
et al.
Journal articles
hal-03504248v1
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Synthesis of 3-substituted indolizidines from amino-ynones derivatives
Huy-Dinh Vu
,
Jacques Renault
,
Thierry Roisnel
,
Nicolas Gouault
,
Philippe Uriac
et al.
Journal articles
hal-01334050v1
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On the formation of a protic ionic liquid in nature.
Li Chen
,
Genevieve E Mullen
,
Myriam Le Roch
,
Cody G Cassity
,
Nicolas Gouault
et al.
Journal articles
istex
hal-01116159v1
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Total synthesis of (-)-epimyrtine by a gold-catalyzed hydroamination approach.
Thi Thanh Huyen Trinh
,
Khanh Hung Nguyen
,
Patricia de Aguiar Amaral
,
Nicolas Gouault
Journal articles
hal-01116168v1
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Designed mono- and di-covalent inhibitors trap modeled functional motions for Trypanosoma cruzi proline racemase in crystallography
Patricia de Aguiar Amaral
,
Delphine Autheman
,
Guilherme Dias de Melo
,
Nicolas Gouault
,
Jean-François Cupif
et al.
Journal articles
hal-01935360v1
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Irreversible inhibitors of the proline racemase (PRAC) unveil innovative mechanism of action as antibacterial against Clostridioides difficile
Cécile Gateau
,
Guilherme Dias de Melo
,
Philippe Uriac
,
Olivier Tasseau
,
Jacques Renault
et al.
Journal articles
hal-03504249v1
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Structure Activity Relationship Studies around DB18, a Potent and Selective Inhibitor of CLK Kinases
Dabbugoddu Brahmaiah
,
Anagani Kanaka Durga Bhavani
,
Pasula Aparna
,
Nangunoori Sampath Kumar
,
Hélène Solhi
et al.
Journal articles
hal-03828358v1
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Electrophilic carbon transfer in gold catalysis: synthesis of substituted chromones
Jacques Renault
,
Zhao Qian
,
Philippe Uriac
,
Nicolas Gouault
Journal articles
istex
hal-00843465v1
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UV-protectant metabolites from lichens and their symbiotic partners.
Khanh-Hung Nguyen
,
Marylene Chollet-Krugler
,
Nicolas Gouault
,
Sophie Tomasi
Journal articles
hal-01069965v1
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Gold-Catalyzed Synthesis of Substituted 3-Trifluoromethylpyrroles from Mesylated Amino Trifluoromethylpropargylic Alcohols
Benjamin Guieu
,
Myriam Le Roch
,
Michèle David
,
Nicolas Gouault
Journal articles
hal-01680989v1
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Gold catalyzed synthesis of pyridones and halopyridones as versatile intermediates towards piperidine structures
Khan Hung Nguyen
,
Trinh Thi Thanh Huyen
,
Sophie Tomasi
,
Philippe Uriac
,
Nicolas Gouault
et al.
N. SECO 50, May 2013, Saint-Trojan-les-Bains (Ile d'Oléron), France
Conference papers
hal-00873157v1
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Total synthesis of dendrobate alkaloid (+)-241D, isosolenopsin and isosolenopsin A: application of a gold-catalyzed cyclization.
Nicolas Gouault
,
Myriam Le Roch
,
Gisele de Campos Pinto
,
Michèle David
Journal articles
hal-00841675v1
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Preparation of photoprotective dihydropyridinone compositions
Nicolas Gouault
,
Hung Nguyen Khahn
,
Sophie Tomasi
,
Karine Costuas
France, Patent n° : WO 2014167225. 2014
Patents
hal-01116163v1
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Reactivity of N-Boc-Protected Amino-Ynones in the Presence of Zinc Chloride: Formation of Acetylenic Cyclic Imines and Their Palladium Complexes
Huy-Dinh Vu
,
Jacques Renault
,
Thierry Roisnel
,
Clémence Robert
,
Philippe Jehan
et al.
Journal articles
istex
hal-01174898v1
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Methanesulfonic Acid Mediated Cyclization and Meyer-Schuster Rearrangement of γ-Amino-ynones: Access to Enantiopure Pyrrolidine Exocyclic Vinylogous Amides
Huy-Dinh Vu
,
Jacques Renault
,
Thierry Roisnel
,
Nicolas Gouault
,
Philippe Uriac
et al.
Journal articles
istex
hal-01114607v1
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Gold-catalyzed synthesis of enantioenriched furfurylamines from amino acids
Benjamin Guieu
,
Myriam Le Roch
,
Michèle David
,
Nicolas Gouault
Journal articles
hal-01188233v1
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Isolation and Structure Identification of Novel Brominated Diketopiperazines from Nocardia ignorata-A Lichen-Associated Actinobacterium
Alba Noël
,
Solenn Ferron
,
Isabelle Rouaud
,
Nicolas Gouault
,
Jean-Pierre Hurvois
et al.
Journal articles
hal-01501268v1
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