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Journal Articles Journal of Tissue Engineering and Regenerative Medicine Year : 2019

Macrophage functions in wound healing

Abstract

Macrophages play a crucial role in regeneration and consecutive phases of wound healing. In this review, we summarise current knowledge on the ontogeny, origin, phenotypical heterogeneity, and functional exchangeability of macrophages participating in these processes. We also describe the genetic, pharmacologic, and bioengineering methods for manipulation of macrophage phenotype and functions and their potential for development of the novel, clinically applicable therapies.

Domains

Genetics
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Dates and versions

hal-01975698 , version 1 (25-01-2019)

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Malgorzata Kloc, Rafik M Ghobrial, Jarek Wosik, Aneta Lewicka, Sławomir Lewicki, et al.. Macrophage functions in wound healing. Journal of Tissue Engineering and Regenerative Medicine, 2019, 13 (1), pp.99-109. ⟨10.1002/term.2772⟩. ⟨hal-01975698⟩
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