%0 Journal Article %T Macrophage functions in wound healing %+ Methodist Hospital Research Institute %+ The University of Texas M.D. Anderson Cancer Center [Houston] %+ University of Houston %+ Military Institute of Hygiene and Epidemiology (WIHE) %+ Institut de Génétique et Développement de Rennes (IGDR) %A Kloc, Malgorzata %A Ghobrial, Rafik M %A Wosik, Jarek %A Lewicka, Aneta %A Lewicki, Sławomir %A Kubiak, Jacek Z %Z We are grateful for the support from William Stamps Farish Fund; Polish Ministry of National Defense project “Kościuszko" # 571/2016/DA to JZK and Polish Ministry of National Defense project “Kościuszko" # 5508/2017/DA to JZK. %< avec comité de lecture %@ 1932-7005 %J Journal of Tissue Engineering and Regenerative Medicine %I John Wiley & Sons Ltd. %V 13 %N 1 %P 99-109 %8 2019-01 %D 2019 %R 10.1002/term.2772 %M 30445662 %K wound healing %K macrophages %K CX3CR1 %K ROCK kinase %K RhoAactin %Z Life Sciences [q-bio]/GeneticsJournal articles %X Macrophages play a crucial role in regeneration and consecutive phases of wound healing. In this review, we summarise current knowledge on the ontogeny, origin, phenotypical heterogeneity, and functional exchangeability of macrophages participating in these processes. We also describe the genetic, pharmacologic, and bioengineering methods for manipulation of macrophage phenotype and functions and their potential for development of the novel, clinically applicable therapies. %G English %2 https://univ-rennes.hal.science/hal-01975698/document %2 https://univ-rennes.hal.science/hal-01975698/file/Macrophage%20functions%20in%20wound%20healing_accepted.pdf %L hal-01975698 %U https://univ-rennes.hal.science/hal-01975698 %~ UNIV-RENNES1 %~ CNRS %~ IFR140 %~ IGDR %~ STATS-UR1 %~ IGDR-CC %~ UR1-UFR-SVE %~ UR1-HAL %~ UR1-SDV %~ TEST-UR-CSS %~ UNIV-RENNES %~ TEST-HALCNRS %~ UR1-BIO-SA