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Article Dans Une Revue ESC Heart Failure Année : 2018

Pulmonary hypertension in chronic heart failure definitions, advances, and unanswered issues

Julien Guihaire
  • Fonction : Auteur
Muriel Salvat
  • Fonction : Auteur
Florian Zores
Thibaud Damy

Résumé

Pulmonary hypertension (PH) is a common and severe complication of heart failure (HF). Consequently, HF is the leading cause of PH. For many years, specialists have attempted to better understand the pathophysiology of PH in HF, to define its prevalence and its impact on prognosis in order to improve the therapeutic management of these patients. Nowadays, despite the recent guidelines published on the subject, several points remain unclear or debated, and until now, no study has demonstrated the efficacy of any treatment. The aim of this review is to report the evolution of the concepts on post-capillary PH (diagnosis, prevalence, prognosis, and therapeutics). The main issues are raised, focusing especially on the link between structural alterations and haemodynamic abnormalities, to discuss the possible reasons for treatment failures and future potential targets.
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Dates et versions

hal-01900653 , version 1 (12-07-2019)

Identifiants

Citer

Emmanuelle Berthelot, Fabrice Bauer, Jean-Christophe Eicher, Erwan Flecher, Barnabas Gellen, et al.. Pulmonary hypertension in chronic heart failure definitions, advances, and unanswered issues. ESC Heart Failure, 2018, 5 (5), pp.755-763. ⟨10.1002/ehf2.12316⟩. ⟨hal-01900653⟩
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