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Journal Articles Tetrahedron Letters Year : 2016

Synthesis of 3-substituted indolizidines from amino-ynones derivatives

Abstract

Two types of indolizidine derivatives can be synthesized from amino-ynones. In the presence of methanesulfonic acid, Meyer-Schuster rearrangement furnished vinylogues of indolizidin-3-ones whereas treatment with zinc chloride gave stable 3-alkynyl-1,5,6,7,8,8a-hexahydroindolizine-zinc complexes that were reduced to 3-alkynylindolizidines.
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Dates and versions

hal-01334050 , version 1 (11-10-2016)

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Huy-Dinh Vu, Jacques Renault, Thierry Roisnel, Nicolas Gouault, Philippe Uriac. Synthesis of 3-substituted indolizidines from amino-ynones derivatives. Tetrahedron Letters, 2016, 57 (27-28), pp.3036--3038. ⟨10.1016/j.tetlet.2016.05.108⟩. ⟨hal-01334050⟩
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