Two-dimensional transthoracic echocardiographic normal reference ranges for proximal aorta dimensions: results from the EACVI NORRE study - Université de Rennes Access content directly
Journal Articles European Heart Journal - Cardiovascular Imaging Year : 2017

Two-dimensional transthoracic echocardiographic normal reference ranges for proximal aorta dimensions: results from the EACVI NORRE study

Anne Bernard
Seisyou Kou
  • Function : Author
Natalia Gonjilashvili
  • Function : Author
George D. Athanassopoulos
  • Function : Author
Daniele Barone
  • Function : Author
Monica Baroni
  • Function : Author
Nuno Cardim
  • Function : Author
Andreas Hagendorff
  • Function : Author
Krasimira Hristova
  • Function : Author
Teresa Lopez
  • Function : Author
  • PersonId : 947834
Gonzalo de La Morena
  • Function : Author
Bogdan A. Popescu
  • Function : Author
Martin Penicka
  • Function : Author
Tolga Ozyigit
  • Function : Author
Jose David Rodrigo Carbonero
  • Function : Author
Nico van de Veire
  • Function : Author
Ralph Stephan von Bardeleben
  • Function : Author
Dragos Vinereanu
  • Function : Author
Jose Luis Zamorano
  • Function : Author
Ann-Stephan Gori
  • Function : Author
Gilbert Habib
Karima Addetia
  • Function : Author
Roberto M. Lang
  • Function : Author
Luigi P. Badano
  • Function : Author

Abstract

AIMS: To report normal reference ranges for echocardiographic dimensions of the proximal aorta obtained in a large group of healthy volunteers recruited using state-of-the-art cardiac ultrasound equipment, considering different measurement conventions, and taking into account gender, age, and body size of individuals. METHODS AND RESULTS: A total of 704 (mean age: 46.0 ± 13.5 years) healthy volunteers (310 men and 394 women) were prospectively recruited from the collaborating institutions of the Normal Reference Ranges for Echocardiography (NORRE) study. A comprehensive echocardiographic examination was obtained in all subjects following pre-defined protocols. Aortic dimensions were obtained in systole and diastole, following both the leading-edge to leading-edge and the inner-edge to inner-edge conventions. Diameters were measured at four levels: ventricular-arterial junction, sinuses of Valsalva, sino-tubular junction, and proximal tubular ascending aorta. Measures of aortic root in the short-axis view following the orientation of each of the three sinuses were also performed. Men had significantly larger body sizes when compared with women, and showed larger aortic dimensions independently of the measurement method used. Dimensions indexed by height and body surface area are provided, and stratification by age ranges is also displayed. In multivariable analysis, the independent predictors of aortic dimensions were age, gender, and height or body surface area. CONCLUSION: The NORRE study provides normal values of proximal aorta dimensions as assessed by echocardiography. Reference ranges for different anatomical levels using different (i) measurement conventions and (ii) at different times of the cardiac cycle (i.e. mid-systole and end-diastole) are provided. Age, gender, and body size were significant determinants of aortic dimensions

Dates and versions

hal-01301541 , version 1 (12-04-2016)

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Daniel Saura, Raluca Dulgheru, Luis Caballero, Anne Bernard, Seisyou Kou, et al.. Two-dimensional transthoracic echocardiographic normal reference ranges for proximal aorta dimensions: results from the EACVI NORRE study. European Heart Journal - Cardiovascular Imaging, 2017, 18 (2), pp.167-179. ⟨10.1093/ehjci/jew053⟩. ⟨hal-01301541⟩
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