Comparing Robotic-Assisted to Open Radical Cystectomy in the Management of Non-Muscle-Invasive Bladder Cancer: A Propensity Score Matched-Pair Analysis - Université de Rennes Access content directly
Journal Articles Cancers Year : 2023

Comparing Robotic-Assisted to Open Radical Cystectomy in the Management of Non-Muscle-Invasive Bladder Cancer: A Propensity Score Matched-Pair Analysis

Valentina Panetta
Georges Mjaess
Romain Diamand
Gregory Verhoest
  • Function : Author
Mathieu Roumiguié
Anne Sophie Bajeot
  • Function : Author
Francesco Soria
  • Function : Author
Chiara Lonati
Claudio Simeone
  • Function : Author
Giuseppe Simone
Umberto Anceschi
  • Function : Author
Paolo Umari
Ashwin Sridhar
John Kelly
  • Function : Author
Laura Mertens
  • Function : Author
Anna Colomer
  • Function : Author
Maria Angela Cerruto
  • Function : Author
Alessandro Antonelli
  • Function : Author
Wojciech Krajewski
  • Function : Author
Thierry Quackels
  • Function : Author
Alexandre Peltier
  • Function : Author
Francesco Montorsi
  • Function : Author
Alberto Briganti
  • Function : Author
Jeremy Teoh
Benjamin Pradere
Marco Moschini
  • Function : Author
Thierry Roumeguère

Abstract

Background: For non-muscle-invasive bladder cancer (NMIBC) requiring radical surgery, limited data are available comparing robotic-assisted radical cystectomy with intracorporeal urinary diversion (iRARC) to open radical cystectomy (ORC). The objective of this study was to compare the two surgical techniques. Methods: A multicentric cohort of 593 patients with NMIBC undergoing iRARC or ORC between 2015 and 2020 was prospectively gathered. Perioperative and pathologic outcomes were compared. Results: A total of 143 patients operated on via iRARC were matched to 143 ORC patients. Operative time was longer in the iRARC group (p = 0.034). Blood loss was higher in the ORC group (p < 0.001), with a consequent increased post-operative transfusion rate in the ORC group (p = 0.003). Length of stay was longer in the ORC group (p = 0.007). Post-operative complications did not differ significantly (all p > 0.05). DFS at 60 months was 55.9% in ORC and 75.2% in iRARC with a statistically significant difference (p = 0.033) found in the univariate analysis. Conclusion: We found that iRARC for patients with NMIBC is safe, associated with a lower blood loss, a lower transfusion rate and a shorter hospital stay compared to ORC. Complication rates were similar. No significant differences in survival analyses emerged across the two techniques.

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hal-04284066 , version 1 (14-11-2023)

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Etienne Courboin, Romain Mathieu, Valentina Panetta, Georges Mjaess, Romain Diamand, et al.. Comparing Robotic-Assisted to Open Radical Cystectomy in the Management of Non-Muscle-Invasive Bladder Cancer: A Propensity Score Matched-Pair Analysis. Cancers, 2023, 15 (19), pp.4732. ⟨10.3390/cancers15194732⟩. ⟨hal-04284066⟩
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