High-Dimensional Phenotyping of Human Myeloid-Derived Suppressor Cells/Tumor-Associated Macrophages in Tissue by Mass Cytometry - Université de Rennes Accéder directement au contenu
Article Dans Une Revue Methods in Molecular Biology Année : 2021

High-Dimensional Phenotyping of Human Myeloid-Derived Suppressor Cells/Tumor-Associated Macrophages in Tissue by Mass Cytometry

Résumé

Myeloid-derived suppressor cells (MDSCs) and tumor-associated macrophages (TAMs) are heterogeneous cells that share myeloid markers and are not easily distinguishable in human tumors due to their lack of specific markers. These cells are a major player in the tumor microenvironment and are involved in the prognosis and physiopathology of various tumors. Here is presented a scheme to decipher these cells by mass cytometry.
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Dates et versions

hal-03099418 , version 1 (06-01-2021)

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Juliette Ferrant, Simon Le Gallou, Guillaume Manson, Steve Genebrier, Frédéric Mourcin, et al.. High-Dimensional Phenotyping of Human Myeloid-Derived Suppressor Cells/Tumor-Associated Macrophages in Tissue by Mass Cytometry. Methods in Molecular Biology, 2021, 2236, pp.57-66. ⟨10.1007/978-1-0716-1060-2_6⟩. ⟨hal-03099418⟩
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