Remotely Controlled Iridium-Catalyzed Asymmetric Hydrogenation of Terminal 1,1-Diaryl Alkenes - Université de Rennes Access content directly
Journal Articles Angewandte Chemie International Edition Year : 2013

Remotely Controlled Iridium-Catalyzed Asymmetric Hydrogenation of Terminal 1,1-Diaryl Alkenes

Abstract

Working together: The presence of a remote directing group on terminal 1,1-diaryl and 1,1-dialkyl alkenes led to high and unprecedented enantioselectivity in iridium-catalyzed asymmetric hydrogenation (see scheme). This strategy offers efficient synthetic pathways towards valuable enantiomerically enriched 1,1-diaryl and 1,1-dialkyl alkanes. Moreover, the directing group can be further functionalized.

Dates and versions

hal-01472915 , version 1 (21-02-2017)

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Tatiana Besset, Rafael Gramage-Doria, Joost N. H. Reek. Remotely Controlled Iridium-Catalyzed Asymmetric Hydrogenation of Terminal 1,1-Diaryl Alkenes. Angewandte Chemie International Edition, 2013, 52, pp.8795 - 8797. ⟨10.1002/anie.201302942⟩. ⟨hal-01472915⟩

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