Vagus nerve stimulation: State of the art of stimulation and recording strategies to address autonomic function neuromodulation - Université de Rennes Access content directly
Journal Articles Journal of Neural Engineering Year : 2016

Vagus nerve stimulation: State of the art of stimulation and recording strategies to address autonomic function neuromodulation

Pascal Couderc
  • Function : Author
Paweł Maciejasz
  • Function : Author
Charles-Henri Malbert
Eloi Marijon
Chloé Picq
  • Function : Author

Abstract

Objective. Neural signals along the vagus nerve (VN) drive many somatic and autonomic functions. The clinical interest of VN stimulation (VNS) is thus potentially huge and has already been demonstrated in epilepsy. However, side effects are often elicited, in addition to the targeted neuromodulation. Approach. This review examines the state of the art of VNS applied to two emerging modulations of autonomic function: heart failure and obesity, especially morbid obesity. Main results. We report that VNS may benefit from improved stimulation delivery using very advanced technologies. However, most of the results from fundamental animal studies still need to be demonstrated in humans.
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Dates and versions

hal-01372361 , version 1 (19-01-2017)

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David Guiraud, David Andreu, Stéphane Bonnet, Guy Carrault, Pascal Couderc, et al.. Vagus nerve stimulation: State of the art of stimulation and recording strategies to address autonomic function neuromodulation. Journal of Neural Engineering, 2016, 13 (4), pp.041002. ⟨10.1088/1741-2560/13/4/041002⟩. ⟨hal-01372361⟩
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