New building blocks or dendritic pseudopeptides for metal chelating
Abstract
Dendritic oligopeptides have been reported as useful building blocks for many interactions. Starting from hydrazine, we described an approach to create new dendritic pseudopeptides linked with biol. systems, such as cell membrane, as chelate metal, Ni2+-nitrilotriacetic acid moieties which could target histidine rich peptides or proteins. Depending on the nature of these new chem. recognition units, they could be integrated into a peptide by coupling in C or N-termini.[Figure not available: see fulltext.].