Leishmania cell wall as a potent target for antiparasitic drugs. A focus on the glycoconjugates - Université de Rennes Access content directly
Journal Articles Organic & Biomolecular Chemistry Year : 2015

Leishmania cell wall as a potent target for antiparasitic drugs. A focus on the glycoconjugates

Abstract

Although leishmaniasis has been studied for over a century, the fight against cutaneous, mucocutaneous and visceral forms of the disease remains a hot topic. This review refers to the parasitic cell wall and more particularly to the constitutive glycoconjugates. The structures of the main glycolipids and glycoproteins, which are species-dependent, are described. The focus is on the disturbance of the lipid membrane by existing drugs and possible new ones, in order to develop future therapeutic agents
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hal-01174899 , version 1 (10-07-2015)

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Yari Cabezas, Laurent Legentil, Florence Robert-Gangneux, Franck Daligault, Sorya Belaz, et al.. Leishmania cell wall as a potent target for antiparasitic drugs. A focus on the glycoconjugates. Organic & Biomolecular Chemistry, 2015, 13 (31), pp.8393-8404. ⟨10.1039/c5ob00563a⟩. ⟨hal-01174899⟩
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