Palladium-catalyzed intramolecular direct arylation of 2-bromobenzenesulfonic acid derivatives. - Université de Rennes Accéder directement au contenu
Article Dans Une Revue Advanced Synthesis and Catalysis Année : 2012

Palladium-catalyzed intramolecular direct arylation of 2-bromobenzenesulfonic acid derivatives.

Résumé

A palladium-catalyzed intramol. direct arylation of 2-bromobenzenesulfonic acid derivs. was found to proceed using 1 mol% of palladium acetate as the catalyst. The influence of the substituents on the phenol moiety of 2-bromobenzenesulfonic acid Ph esters reveals that electron-donating substituents favor the reaction while electron-withdrawing ones are unfavorable. The reactivity of sulfonamides was also studied and, in all cases, a selective activation at sp2 C-H vs. sp3 C-H was obsd. A sulfonamide bearing both Ph and benzyl substituents on nitrogen gave selectively the six-membered ring product. [on SciFinder(R)]

Dates et versions

hal-01070074 , version 1 (30-09-2014)

Identifiants

Citer

Charles Beromeo Bheeter, Jitendra K. Bera, Henri. Doucet. Palladium-catalyzed intramolecular direct arylation of 2-bromobenzenesulfonic acid derivatives.. Advanced Synthesis and Catalysis, 2012, 354, pp.3533--3538. ⟨10.1002/adsc.201200793⟩. ⟨hal-01070074⟩
51 Consultations
0 Téléchargements

Altmetric

Partager

Gmail Facebook X LinkedIn More