Unexpected selectivity in ruthenium-catalyzed hydrosilylation of primary amides: synthesis of secondary amines. - Université de Rennes Accéder directement au contenu
Article Dans Une Revue Chemical Communications Année : 2013

Unexpected selectivity in ruthenium-catalyzed hydrosilylation of primary amides: synthesis of secondary amines.

Résumé

Selective ruthenium-catalyzed reductive coupling of primary amides under hydrosilylation conditions is achieved using an one pot procedure. Using 3 equiv. of phenylsilane and [RuCl2(mesitylene)]2 (1-2 mol%) as the catalyst at 100 °C under neat conditions, secondary symmetric amines were obtained in good yields and with high chemoselectivities.

Domaines

Catalyse
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Dates et versions

hal-00879855 , version 1 (05-11-2013)

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Citer

Bin Li, Jean-Baptiste Sortais, Christophe Darcel. Unexpected selectivity in ruthenium-catalyzed hydrosilylation of primary amides: synthesis of secondary amines.. Chemical Communications, 2013, 49 (35), pp.3691-3. ⟨10.1039/c3cc39149c⟩. ⟨hal-00879855⟩
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