Synthesis of New 3-heteroaryl-2-phenylquinolines and their Pharmacological Activity as Antimicrobial Agents - Université de Rennes Access content directly
Journal Articles Letters in Organic Chemistry Year : 2013

Synthesis of New 3-heteroaryl-2-phenylquinolines and their Pharmacological Activity as Antimicrobial Agents

Abstract

Some new unfused tricyclic aromatic systems containing various heterocyclic cores were synthesized. These compounds were prepared in good yields via appropriate routes using 6-methyl-2-phenylquinoline-3-carbaldehyde as a key intermediate. The antibacterial activity of the prepared compounds was evaluated against: Escherichia coli, Staphylococcus aureus, Pseudomonas aeruginosa, Klebsiella pneumonia and Salmonella thipymurium using the disk-diffusion method. The minimum inhibitory concentration (MIC) was determined for the tested compounds.
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hal-00871959 , version 1 (11-10-2013)

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Saida Benzerka, Abdelmalek Bouraiou, Sofiane Bouacida, Thierry Roisnel, Chafia Bentchouala, et al.. Synthesis of New 3-heteroaryl-2-phenylquinolines and their Pharmacological Activity as Antimicrobial Agents. Letters in Organic Chemistry, 2013, 10 (2), pp.94-99. ⟨10.2174/1570178611310020005⟩. ⟨hal-00871959⟩
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