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Structure: Internal structure identifier : 542078
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From Quinoxaline, Pyrido[2,3-b]pyrazine and Pyrido[3,4-b]pyrazine to Pyrazino-Fused Carbazoles and Carbolines

Frédéric Lassagne , Timothy Langlais , Elsa Caytan , Emmanuelle Limanton , Ludovic Paquin et al.
Molecules, 2018, 23 (11), pp.2961. ⟨10.3390/molecules23112961⟩
Journal articles hal-03867783v1
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Reactivity Under Microwave Irradiation of 2-amino 4H-chromene-3-carbonitrile as tool for the construction of potential bioactive derivatives

Ali Bouattour , Mehdi Fakhfakh , Houcine Ammar , Ludovic Paquin , Jean-Pierre Bazureau et al.
3rd International Electronic Conference on Medicinal Chemistry, Nov 2022, Online, France
Conference papers hal-03872422v1
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Practical approach to N-benzyl derivatives of 2-amino-8-methoxy-4H-chromene-3-carbonitrile by reductive amination: Exploration of their effects against protein kinases and in silico ADME profiling

Marwa Dhiabi , Ali Bouattour , Mehdi Fakhfakh , Souhir Abid , Ludovic Paquin et al.
Journal of Molecular Structure, 2023, 1274 (Part 1), pp.134319. ⟨10.1016/j.molstruc.2022.134319⟩
Journal articles hal-03867314v1
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Re-annotation, improved large-scale assembly and establishment of a catalogue of noncoding loci for the genome of the model brown alga Ectocarpus

Alexandre Cormier , Komlan Avia , Lieven Sterck , Thomas Derrien , Valentin Wucher et al.
New Phytologist, 2017, 214 (1), pp.219-232. ⟨10.1111/nph.14321⟩
Journal articles hal-03145812v1
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Thiazolo[5,4- f ]quinoxalines, Oxazolo[5,4- f ]quinoxalines and Pyrazino[ b,e ]isatins: Synthesis from 6-Aminoquinoxalines and Properties

Frédéric Lassagne , Joshua M. Sims , William Erb , Olivier Mongin , Nicolas Richy et al.
European Journal of Organic Chemistry, 2021, 2021 (19), pp.2756-2763. ⟨10.1002/ejoc.202100362⟩
Journal articles hal-03269555v1
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Copper stress proteomics highlights local adaptation of two strains of the model brown alga Ectocarpus siliculosus

Andrés A Ritter , Martin Ubertini , Sarah Romac , Fanny Gaillard , Ludovic Delage et al.
Proteomics, 2010, 10 (11), pp.2074 - 2088. ⟨10.1002/pmic.200900004⟩
Journal articles hal-01925564v1
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Metabolic Complementarity Between a Brown Alga and Associated Cultivable Bacteria Provide Indications of Beneficial Interactions

Bertille Burgunter-Delamare , Hetty Kleinjan , Clémence Frioux , Enora Fremy , Margot Wagner et al.
Frontiers in Marine Science, 2020, 7, pp.1-11. ⟨10.3389/fmars.2020.00085⟩
Journal articles hal-02866101v2
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Insights into the potential for mutualistic and harmful host‐microbe interactions affecting brown alga freshwater acclimation

Hetty Kleinjan , Clémence Frioux , Gianmaria Califano , Méziane Aite , Enora Fremy et al.
Molecular Ecology, In press, 32 (3), pp.703-723. ⟨10.1111/mec.16766⟩
Journal articles hal-03868898v1
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Nigratine as first-in-class dual inhibitor of necroptosis and ferroptosis regulated cell death

Claire Delehouzé , Arnaud Comte , Marcelle Hauteville , Peter G Goekjian , Marie-Thérèse Dimanche-Boitrel et al.
2022
Preprints, Working Papers, ... hal-03867390v1
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Cyanorak v2.1: a scalable information system dedicated to the visualization and expert curation of marine and brackish picocyanobacteria genomes

Laurence Garczarek , Ulysse Guyet , Hugo Doré , Gregory Farrant , Mark Hoebeke et al.
Nucleic Acids Research, 2021, 49 (D1), pp.D667-D676. ⟨10.1093/nar/gkaa958⟩
Journal articles hal-02988562v1
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Targeted Laser Ablation in the Embryo of Saccharina latissima

Samuel Boscq , Stéphanie Dutertre , Ioannis Theodorou , Bénédicte Charrier
Journal of visualized experiments : JoVE, In press, ⟨10.3791/63518⟩
Journal articles hal-03601527v1

Synthesis of N-pyridyl azoles using a deprotometalation-iodolysis-N-arylation sequence and evaluation of their antiproliferative activity in melanoma cells

Madani Hedidi , Julien Maillard , William Erb , Frédéric Lassagne , Yury Halauko et al.
Tetrahedron, 2016, 72 (39), pp.6467 - 6476. ⟨10.1016/j.tet.2016.08.056⟩
Journal articles hal-03875302v1
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The genome of Ectocarpus subulatus -a highly stress-tolerant brown alga

Simon M. Dittami , Erwan Corre , Loraine Brillet-Guéguen , Agnieszka Lipinska , Méziane Aite et al.
2019
Preprints, Working Papers, ... hal-02333021v1
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Peptimapper: proteogenomics workflow for the expert annotation of eukaryotic genomes

Laetitia Guillot , Ludovic Delage , Alain Viari , Yves Vandenbrouck , Emmanuelle Com et al.
BMC Genomics, 2019, 20 (1), pp.56. ⟨10.1186/s12864-019-5431-9⟩
Journal articles hal-01987197v1
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Oxazolo[5,4-f]quinoxaline-type selective inhibitors of glycogen synthase kinase-3α (GSK-3α): Development and impact on temozolomide treatment of glioblastoma cells

Mohamed Hasyeoui , Frédéric Lassagne , William Erb , Manal Nael , Khaled Elokely et al.
Bioorganic Chemistry, 2023, 134, pp.106456. ⟨10.1016/j.bioorg.2023.106456⟩
Journal articles hal-04059446v1

Identification of Novel Compounds Inhibiting the Kinase Activity of the CDK5/p25 Complex via Direct Binding to p25

Riheb Jabeur , Caroline Corbel , Pascal Loyer , Annabelle Le Parc , Adelaide Le Grand et al.
Biochemistry, 2023, 62 (9), pp.1452-1463. ⟨10.1021/acs.biochem.2c00691⟩
Journal articles hal-04089029v1

Microwave-assisted practical synthesis of 4-imino-3-phenyl-3,4-dihydro-1H-chromeno[2,3-d]pyrimidine-2(5H)-thione derivatives and exploration of their biological activities

A. Bouattour , M. Fakhfakh , S. Abid , L. Paquin , A. Corlu et al.
ARKIVOC - Online Journal of Organic Chemistry, 2017, 2017 (4), pp.291--302. ⟨10.24820/ark.5550190.p010.040⟩
Journal articles hal-01581215v1

Comparative Transcriptome Analysis Provides Insights into Response of Ulva compressa to Fluctuating Salinity Conditions

Qikun Xing , Guiqi Bi , Min Cao , Arnaud Belcour , Méziane Aite et al.
Journal of Phycology, 2021, 57 (4), pp.1295-1308. ⟨10.1111/jpy.13167⟩
Journal articles hal-03334031v1
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From benzofuro-, benzothieno- and 10-methylindolo-[2,3-b]-fused benzothiopyrano[4,3,2-de]quinolines to the corresponding benzothiopyrano[4,3,2-de]1,8-naphthyridines: synthesis and properties of these hexacyclic heteroaromatic compounds

Nicolas Mast , William Erb , Lionel Nauton , Pascale Moreau , Olivier Mongin et al.
New Journal of Chemistry, 2022, 47 (1), pp.258-283. ⟨10.1039/D2NJ04567B⟩
Journal articles hal-03904365v1
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Structure Activity Relationship Studies around DB18, a Potent and Selective Inhibitor of CLK Kinases

Dabbugoddu Brahmaiah , Anagani Kanaka Durga Bhavani , Pasula Aparna , Nangunoori Sampath Kumar , Hélène Solhi et al.
Molecules, 2022, 27 (19), pp.6149. ⟨10.3390/molecules27196149⟩
Journal articles hal-03828358v1
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Betulin, a Newly Characterized Compound in Acacia auriculiformis Bark, Is a Multi-Target Protein Kinase Inhibitor

Augustine A. Ahmadu , Claire Delehouze , Anas Haruna , Lukman Mustapha , Bilqis A. Lawal et al.
Molecules, 2021, 26 (15), pp.4599. ⟨10.3390/molecules26154599⟩
Journal articles hal-03331756v1

Semi-Quantitative Targeted Gas Chromatography-Mass Spectrometry Profiling Supports a Late Side-Chain Reductase Cycloartenol-to-Cholesterol Biosynthesis Pathway in Brown Algae

Jean Girard , Goulven Lanneau , Ludovic Delage , Cédric Leroux , Arnaud Belcour et al.
Frontiers in Plant Science, 2021, 12, ⟨10.3389/fpls.2021.648426⟩
Journal articles hal-04044618v1
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Consequences of blunting the mevalonate pathway in cancer identified by a pluriomics approach

Sophie Goulitquer , Mikael Croyal , Julie Lalande , Anne-Lise Royer , Yann Guitton et al.
Cell Death and Disease, 2018, 9 (7), pp.745. ⟨10.1038/s41419-018-0761-0⟩
Journal articles hal-02140936v1
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2-Aminophenones, a common precursor to N-aryl isatins and acridines endowed with bioactivities

Nahida Mokhtari Brikci-Nigassa , Ghenia Bentabed-Ababsa , William Erb , Floris Chevallier , Laurent Picot et al.
Tetrahedron, 2018, 74 (15), pp.1785-1801. ⟨10.1016/j.tet.2018.02.038⟩
Journal articles hal-01774406v1
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The genome of Ectocarpus subulatus – A highly stress-tolerant brown alga

Simon M. Dittami , Erwan Corre , Loraine Brillet-Guéguen , Agnieszka Lipinska , Noé Pontoizeau et al.
Marine Genomics, 2020, 52, pp.100740. ⟨10.1016/j.margen.2020.100740⟩
Journal articles hal-02866117v1
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Using automated reasoning to explore the metabolism of unconventional organisms: a first step to explore host–microbial interactions

Clémence Frioux , Simon Dittami , Anne Siegel
Biochemical Society Transactions, 2020, 48 (3), pp.901-913. ⟨10.1042/BST20190667⟩
Journal articles hal-02569935v1
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Semi-Quantitative Targeted Gas Chromatography-Mass Spectrometry Profiling Supports a Late Side-Chain Reductase Cycloartenol-to-Cholesterol Biosynthesis Pathway in Brown Algae

Jean Girard , Goulven Lanneau , Ludovic Delage , Cédric Leroux , Arnaud Belcour et al.
Frontiers in Plant Science, 2021, 12, pp.1-10. ⟨10.3389/fpls.2021.648426⟩
Journal articles hal-03222505v1
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Inferring Biochemical Reactions and Metabolite Structures to Understand Metabolic Pathway Drift

Arnaud Belcour , Jean Girard , Méziane Aite , Ludovic Delage , Camille Trottier et al.
iScience, 2020, 23 (2), pp.100849. ⟨10.1016/j.isci.2020.100849⟩
Journal articles hal-01943880v2
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Robustness analysis of metabolic predictions in algal microbial communities based on different annotation pipelines

Elham Karimi , Enora Geslain , Arnaud Belcour , Clémence Frioux , Méziane Aite et al.
PeerJ, 2021, 9, pp.1-24. ⟨10.7717/peerj.11344⟩
Journal articles hal-03223662v1
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Genome–Scale Metabolic Networks Shed Light on the Carotenoid Biosynthesis Pathway in the Brown Algae Saccharina japonica and Cladosiphon okamuranus

Delphine Nègre , Méziane Aite , Arnaud Belcour , Clémence Frioux , Loraine Brillet-Guéguen et al.
Antioxidants , 2019, 8 (11), pp.564. ⟨10.3390/antiox8110564⟩
Journal articles hal-02395080v1