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authIdHal_s : raphael-metivier
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Nuclear translocation of MRTFA in MCF7 breast cancer cells shifts ERα nuclear/genomic to extra-nuclear/non genomic actions

Charly Jehanno , Frédéric Percevault , Noureddine Boujrad , Pascale Le Goff , Coralie Fontaine et al.
Molecular and Cellular Endocrinology, 2021, 530, pp.111282. ⟨10.1016/j.mce.2021.111282⟩
Journal articles hal-03221142v1

Codon adaptation by synonymous mutations impacts the functional properties of the estrogen receptor-alpha protein in breast cancer cells

Léa Clusan , Frederic Percevault , Emmanuelle Jullion , Pascale Le Goff , Christophe Tiffoche et al.
Molecular Oncology, 2023, ⟨10.1002/1878-0261.13399⟩
Journal articles hal-04058869v1
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Mutation of Arginine 264 on ERα (Estrogen Receptor Alpha) Selectively Abrogates the Rapid Signaling of Estradiol in the Endothelium Without Altering Fertility

Marine Adlanmerini , Chanaëlle Febrissy , Rana Zahreddine , Emilie Vessières , Melissa Buscato et al.
Arteriosclerosis, Thrombosis, and Vascular Biology, 2020, 40 (9), pp.2143-2158. ⟨10.1161/ATVBAHA.120.314159⟩
Journal articles hal-02929719v1

The human estrogen receptor-alpha isoform hERalpha46 antagonizes the proliferative influence of hERalpha66 in MCF7 breast cancer cells

Graziella Penot , Christine Le Péron , Yohann Mérot , Eva Grimaud-Fanouillere , François Ferrière et al.
Endocrinology, 2005, 146, pp.5474-84. ⟨10.1210/en.2005-0866⟩
Journal articles hal-00015993v1
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New stably transfected bioluminescent cells expressing FLAG epitope-tagged estrogen receptors to study their chromatin recruitment.

Eric Badia , Aurélie Escande , Patrick Balaguer , Raphaël Métivier , Vincent Cavailles et al.
BMC Biotechnology, 2009, 9, pp.77. ⟨10.1186/1472-6750-9-77⟩
Journal articles inserm-00419701v1

The endocrine disruptor monoethyl-hexyl-phthalate is a selective peroxisome proliferator-activated receptor gamma modulator that promotes adipogenesis.

Jérôme N Feige , Laurent Gelman , Daniel Rossi , Vincent Zoete , Raphaël Métivier et al.
Journal of Biological Chemistry, 2007, 282 (26), pp.19152-66. ⟨10.1074/jbc.M702724200⟩
Journal articles hal-00177041v1

Dynamics of ERa-mediated transcriptional activation of responsive genes ex vivo.

Raphaël Métivier , Rozenn Gallais , Christophe Tiffoche , Christine Le Péron , R. Jurkowska et al.
Annual meeting of the French society of Endocrinology, Mar 2007, Caen, France
Conference papers hal-00493891v1
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Changes in Gene Expression and Estrogen Receptor Cistrome in Mouse Liver Upon Acute E2 Treatment

Gaëlle Palierne , Aurelie J Fabre , Romain Solinhac , Christine Le Peron , Stéphane Avner et al.
Molecular Endocrinology -Baltimore-, 2016, 30 (7), pp.709-732. ⟨10.1210/me.2015-1311⟩
Journal articles hal-01357623v1
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The antagonist properties of Bazedoxifene after acute treatment are shifted to stimulatory action after chronic exposure in the liver but not in the uterus

Mélissa Buscato , Coralie Fontaine , Aurélie Fabre , Alexia Vinel , Marie-Cécile Valera et al.
Molecular and Cellular Endocrinology, 2018, 472 (472), pp.87-96. ⟨10.1016/j.mce.2017.11.022⟩
Journal articles hal-01812522v1

Reprogrammation des cellules MCF7 issues de cancer du sein par hyperhydroxymethylation de l’ADN

Audrey Laurent , Christine Le Peron , Maud Bizot , Stéphane Avner , Raphaël Metivier et al.
EpiPhase 2019, Jun 2019, Toulouse, France
Conference papers hal-02181066v1

Transcription in four dimensions: nuclear receptor-directed initiation of gene expression

Raphaël Métivier , G. Reid , F. Gannon
EMBO Reports, 2006, 7 (2), pp.161-167. ⟨10.1038/sj.embor.7400626⟩
Journal articles hal-00022120v1

Estrogen Receptor Transcriptional Activity: A Dynamic Integration of Multi-Leveled Information.

S. Cunha , J. Quintin , Aurélien Sérandour , Vincent Legagneux , Gaëlle Palierne et al.
Keystone Symposia on Nuclear Receptors: Signaling, Gene Regulation and Cancer, Mar 2010, Keystone, United States
Conference papers hal-00493914v1
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Estetrol prevents western diet-induced obesity and atheroma independently of hepatic estrogen receptor (ER)α

Melissa Buscato , Morgane Davezac , Rana Zahreddine , Marine Adlanmerini , Raphaël Métivier et al.
AJP - Endocrinology and Metabolism, 2021, 320 (1), pp.E19-E29. ⟨10.1152/ajpendo.00211.2020⟩
Journal articles hal-03006849v1

Coxsackie and adenovirus receptor is a target and a mediator of estrogen action in breast cancer.

David Vindrieux , Ludovic Le Corre , Jer-Tsong Hsieh , Raphaël Métivier , Pauline Escobar et al.
Endocrine-Related Cancer, 2011, 18 (3), pp.311-21. ⟨10.1530/ERC-10-0230⟩
Journal articles hal-01117400v1

CBP Is a Dosage-Dependent Regulator of Nuclear Factor-{kappa}B Suppression by the Estrogen Receptor.

Kendall W Nettles , German Gil , Jason Nowak , Raphaël Métivier , Vandana B Sharma et al.
Molecular Endocrinology -Baltimore-, 2008, 22 (2), pp.263-272. ⟨10.1210/me.2007-0324⟩
Journal articles hal-00250019v1

Dynamique de l'activation de la transcription d'un gène. [Activation of gene transcription].

Raphaël Métivier
médecine/sciences, 2004, 20 (4), pp.391-3. ⟨10.1051/medsci/2004204391⟩
Journal articles hal-00358354v1

Dynamic CpG Methylation and gene transcriptional regulation by Nuclear Receptors

Raphaël Métivier , Rozenn Gallais , Christophe Tiffoche , Christine Le Péron , Renata Z. Jurkowska et al.
Nuclear Receptor EMBO Conference, May 2007, Gardone Rivieira, Italy
Conference papers hal-00493900v1
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Dynamic ER Interactomes Control the Estrogen-Responsive Trefoil Factor (TFF) Locus Cell-Specific Activities.

Justine Quintin , Christine Le Péron , Gaëlle Palierne , Maud Bizot , Stéphanie Cunha et al.
Molecular and Cellular Biology, 2014, 34 (13), pp.2418-2436. ⟨10.1128/MCB.00918-13⟩
Journal articles hal-00984591v1

Regulation of transcription : A dynamic integration of multi-leveled information.

Raphaël Métivier
Journées scientifique de l'IRTSV, Dec 2008, Grenoble, France
Conference papers hal-00493917v1
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Nuclear accumulation of MKL1 in luminal breast cancer cells impairs genomic activity of ERα and is associated with endocrine resistance

Charly Jehanno , Tamara Fernández-Calero , Denis Habauzit , Stéphane Avner , Frédéric Percevault et al.
Biochimica et Biophysica Acta - Gene Regulatory Mechanisms , 2020, 1863 (5), pp.194507. ⟨10.1016/j.bbagrm.2020.194507⟩
Journal articles hal-02565572v1
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The AF-1-deficient estrogen receptor ERα46 isoform is frequently expressed in human breast tumors

Elodie Chantalat , Frédéric Boudou , Henrik Laurell , Gaëlle Palierne , René Houtman et al.
Breast Cancer Research, 2016, 18 (1), pp.123. ⟨10.1186/s13058-016-0780-7⟩
Journal articles inserm-01412032v1

Cell specific regulation of estrogen receptor alpha transactivation.

Guillaume Huet , Yohann Mérot , François Le Dily , Noureddine Boujrad , Raphaël Métivier et al.
Nuclear Receptor EMBO Conference, May 2007, Gardone Rivieira, Italy
Conference papers hal-00493429v1

Epigenetic switch involved in activation of pioneer factor FOXA1-dependent enhancers.

Aurélien A. Sérandour , Stéphane Avner , Frédéric Percevault , Florence Demay , Maud Bizot et al.
Genome Research, 2011, 21 (4), pp.555-65. ⟨10.1101/gr.111534.110⟩
Journal articles hal-00587841v1

Defining specificity of transcription factor regulatory activities.

Jérôme Eeckhoute , Raphaël Métivier , Gilles Salbert
Journal of Cell Science, 2009, 122 (Pt 22), pp.4027-34. ⟨10.1242/jcs.054916⟩
Journal articles hal-00436576v1

Dynamics of ER-mediated Transcriptional Activation of Responsive Genes In vivo. Chromatin dynamics and epigenetics

Raphaël Métivier , Rozenn Gallais , Christophe Tiffoche , Christine Le Péron , R. Jurkowska et al.
Chromatin dynamics and epigenetics, Mar 2007, Liège, Belgium
Conference papers hal-00493887v1

Are 'omics of estrogen receptors defining potential targets for breast cancer treatment?

Raphaël Métivier
Epigenomics, 2011, 3 (5), pp.525-8. ⟨10.2217/epi.11.81⟩
Journal articles hal-00750126v1

The relative contribution exerted by AF-1 and AF-2 transactivation functions in estrogen receptor alpha transcriptional activity depends upon the differentiation stage of the cell.

Yohann Mérot , Raphaël Métivier , Graziella Penot , Dominique Manu , Christian Saligaut et al.
Journal of Biological Chemistry, 2004, 279 (25), pp.26184-91. ⟨10.1074/jbc.M402148200⟩
Journal articles hal-00295059v1

Functional connection between deimination and deacetylation of histones.

Hélène Denis , Rachel Deplus , Pascale Putmans , Michiyuki Yamada , Raphaël Métivier et al.
Molecular and Cellular Biology, 2009, 29 (18), pp.4982-93. ⟨10.1128/MCB.00285-09⟩
Journal articles hal-00416522v1
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The different natural estrogens promote endothelial healing through distinct cell targets

Morgane Davezac , Rana Zahreddine , Melissa Buscato , Natalia F. Smirnova , Chanaëlle Febrissy et al.
JCI Insight, 2023, 8 (5), ⟨10.1172/jci.insight.161284⟩
Journal articles hal-04040711v1
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Dynamic hydroxymethylation of deoxyribonucleic acid marks differentiation-associated enhancers.

Aurélien A. Sérandour , Stéphane Avner , Frédérik Oger , Maud Bizot , Frédéric Percevault et al.
Nucleic Acids Research, 2012, 40 (17), pp.8255-65. ⟨10.1093/nar/gks595⟩
Journal articles inserm-00716879v1