Search - Université de Rennes Access content directly

Filter your results

14 Results
authIdHal_s : philippe-paul-juin

Structure-activity relationship of selected polyphenol derivatives as inhibitors of Bax/Bcl-xL interaction.

Duc Duy Vo , Fabien Gautier , Philippe Juin , René Grée
European Journal of Medicinal Chemistry, 2012, 51, pp.286-93. ⟨10.1016/j.ejmech.2012.02.036⟩
Journal articles istex hal-00841554v1

Synthesis and cytotoxicity studies of newly designed benzyl-hydroquinone derivatives

Olivier Tasseau , Paul Mosset , Sophie C Barillé-Nion , Fabien Gautier , Philippe Juin et al.
Medicinal Chemistry Research, 2018, 27 (4), pp.1050-1065. ⟨10.1007/s00044-017-2127-z⟩
Journal articles hal-01771097v1

The small organic compound HA14-1 sensitizes human glioblastoma cells to induction of cell death through inhibition of Bcl-2.

F. Manero , F. Gautier , T. Gallenne , N. Cauquil , D. Grée et al.
Cancer Research, 2006, 66, pp.2757-2764
Journal articles hal-00322859v1
Image document

Preliminary Studies on the Activity of Mixed Polyphenol-Heterocyclic Systems Against B16-F10 Melanoma Cancer Cells

Duc Duy Vo , Isabelle Rouaud , Françoise Lohézic-Le Dévéhat , Fabien Gautier , Sophie Barillé-Nion et al.
Medicinal Chemistry, 2016
Journal articles inserm-01406309v1
Image document

An EMT-primary cilium-GLIS2 signaling axis regulates mammogenesis and claudin-low breast tumorigenesis

Molly M Wilson , Céline Callens , Matthieu Le Gallo , Svetlana Mironov , Qiong Ding et al.
Science Advances , 2021, 7 (44), pp.eabf6063. ⟨10.1126/sciadv.abf6063⟩
Journal articles hal-03420207v1

Mitochondrial targeting by use of lipid nanocapsules loaded with SV30, an analogue of the small-molecule Bcl-2 inhibitor HA14-1.

M. Weyland , F. Manero , A. Paillard , Danielle Gree , Guillaume Viault et al.
Journal of Controlled Release, 2011, 151 (1), pp.74-82. ⟨10.1016/j.jconrel.2010.11.032⟩
Journal articles istex hal-00842655v1
Image document

Synthesis and biological studies of new piperidino-1,2,3-triazole hybrids with 3-aryl isoxazole side chains

Appala Venkata Ramana Murthy , Vennu Narendar , Nangunoori Sampath Kumar , Pasula Aparna , Anagani Kanaka Durga Bhavani et al.
Bioorganic & Medicinal Chemistry Letters, 2021, 52, pp.128390. ⟨10.1016/j.bmcl.2021.128390⟩
Journal articles hal-03414697v1

Synthesis of new mixed phenol/heterocyclic derivatives and studies of their activity as inhibitors of Bax/Bcl-xL interaction

Duc Duy Vo , Fabien Gautier , Sophie Barillé-Nion , Philippe Juin , Nicolas Levoin et al.
Tetrahedron, 2014, 70 (2), pp.301-311. ⟨10.1016/j.tet.2013.11.060⟩
Journal articles hal-01114411v1

HA 14-1, a small molecule inhibitor of Bcl-2, bypasses chemo-resistance in leukaemia cells.

L. Oliver , B. Mahé , R. Grée , F.M. Vallette , P. Juin et al.
Leukemia Research, 2007, 31, pp.859-863
Journal articles hal-00323090v1

Hemisynthesis of selected embelin analogs and investigation of their proapoptotic activity against cancer cells

Guillaume Viault , Katragadda Suresh Babu , Fabien Gautier , Sophie Barillé-Nion , Philippe Juin et al.
Medicinal Chemistry (Shāriqah (United Arab Emirates)), 2013, 9 (8), pp.1028--1034. ⟨10.2174/1573406411309080003⟩
Journal articles hal-01147397v1

Design, synthesis and biological evaluation of new inhibitors of Bax/Bcl-xL interaction in cancer cells.

Duc Duy Vo , Fabien Gautier , Sophie Barillé-Nion , Philippe Juin , Nicolas Levoin et al.
Bioorganic and Medicinal Chemistry Letters, 2014, 24 (7), pp.1758-61. ⟨10.1016/j.bmcl.2014.02.035⟩
Journal articles hal-01116303v1

Synthesis of new selected analogues of the proapoptotic and anticancer molecule HA 14-1.

D. Grée , S. Vorin , V.L. Manthati , F. Caijo , G. Viault et al.
Tetrahedron Letters, 2008, 49, pp.3276-3278
Journal articles hal-00323433v1

Corrigendum to “Synthesis of new mixed phenol/heterocyclic derivatives and studies of their activity as inhibitors of Bax/Bcl-xL interaction” [Tetrahedron 70 (2014) 301–311]

Duc Duy Vo , Fabien Gautier , Sophie Barillé-Nion , Philippe Juin , Nicolas Levoin et al.
Tetrahedron, 2014, 70 (33), pp.4977. ⟨10.1016/j.tet.2014.05.062⟩
Journal articles hal-01153823v1
Image document

A combination of in-silico and SAR studies to identify binding hot spots of Bcl-xL inhibitors

Nicolas Levoin , Duc Duy Vo , Fabien Gautier , Sophie Barillé-Nion , Philippe Juin et al.
Bioorganic and Medicinal Chemistry, 2015, 23 (8), pp.1747-1757. ⟨10.1016/j.bmc.2015.02.060⟩
Journal articles hal-01133213v1