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A Practical Approach to New (5Z) 2-Alkylthio-5-arylmethylene- 1-methyl-1,5-dihydro-4H-imidazol-4-one Derivatives
Khadidja Bourahla
,
Ludovic Paquin
,
Olivier Lozach
,
Laurent Meijer
,
François Carreaux
et al.
Journal articles
hal-00870301v1
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Dérivés d'imidazolones, procédé de préparation et applications biologiques.
J.P. Bazureau
,
François Carreaux
,
Stéven Renault
,
Laurent Meijer
,
Olivier Lozach
et al.
Patent n° : FR 291 9608 (A1). 2009
Patents
hal-00411458v1
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Synthesis and preliminary biological evaluation of new derivatives of the marine alkaloid leucettamine B as kinase inhibitors.
Mansour Debdab
,
Stéven Renault
,
Olivier Lozach
,
Laurent Meijer
,
Ludovic Paquin
et al.
Journal articles
istex
hal-00869769v1
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Leucettines, a class of potent inhibitors of cdc2-like kinases and dual specificity, tyrosine phosphorylation regulated kinases derived from the marine sponge leucettamine B: modulation of alternative pre-RNA splicing.
Mansour Debdab
,
François Carreaux
,
Steven Renault
,
Meera Soundararajan
,
Oleg Fedorov
et al.
Journal articles
hal-00870007v1
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Substitution of unsaturated lipid chains by thioether-containing lipid chains in cationic amphiphiles: physicochemical consequences and application for gene delivery
Amal Bouraoui
,
Mathieu Berchel
,
Rosy Ghanem
,
Véronique Vie
,
Gilles Paboeuf
et al.
Journal articles
hal-02088106v1
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An expeditious, environment-friendly, and microwave-assisted synthesis of 5-isatinylidenerhodanine derivatives
Abdelmounaim Safer
,
Mustapha Rahmouni
,
François Carreaux
,
Ludovic Paquin
,
Olivier Lozach
et al.
Journal articles
hal-00869920v1
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Synthesis of new pyridazino[4,5-b]indol-4-ones and pyridazin-3(2H)-one analogs as DYRK1A inhibitors
Amélie Bruel
,
Romain Bénéteau
,
Mylène Chabanne
,
Olivier Lozach
,
Rémy Le Guevel
et al.
Journal articles
hal-01086026v1
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Novel Tetrahydropyrido[1,2- a ]isoindolone Derivatives (Valmerins): Potent Cyclin-Dependent Kinase/Glycogen Synthase Kinase 3 Inhibitors with Antiproliferative Activities and Antitumor Effects in Human Tumor Xenografts
Rajâa Boulahjar
,
Aziz Ouach
,
Chiurato Matteo
,
Stéphane Bourg
,
Myriam Ravache
et al.
Journal articles
hal-02904751v1
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Novel optimization of valmerins (tetrahydropyrido[1,2-a]isoindolones) as potent dual CDK5/GSK3 inhibitors
Aziz Ouach
,
Rajâa Boulahjar
,
Christine Vala
,
Stéphane Bourg
,
Pascal Bonnet
et al.
Journal articles
hal-01295635v1
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An efficient method for the preparation of new analogs of Leucettamine B under solvent-free microwave irradiation.
Mansour Debdab
,
Stéven Renault
,
Samar Eid
,
Olivier Lozach
,
Laurent Meijer
et al.
Heterocycles, 2009, pp.1191-1203
Journal articles
hal-00411456v1
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Novel Tetrahydropyrido[1,2-a]isoindolone Derivatives (Valmerins): Potent Cyclin-Dependent Kinase/Glycogen Synthase Kinase 3 Inhibitors with Antiproliferative Activities and Antitumor Effects in Human Tumor Xenografts
Rajâa Boulahjar
,
Aziz Ouach
,
Chiurato Matteo
,
Stéphane Bourg
,
Myriam Ravache
et al.
Journal of Medicinal Chemistry, 2012, 55, pp.9589-9606
Journal articles
hal-00785213v1
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Synthesis and kinase inhibitory activity of novel substituted indigoids.
Anne Beauchard
,
Hélène Laborie
,
Hervé Rouillard
,
Olivier Lozach
,
Yoan Ferandin
et al.
Journal articles
istex
hal-00416031v1
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Azine and Diazine Functionalization Using 2,2,6,6-Tetramethylpiperidino-Based Lithium–Metal Combinations: Application to the Synthesis of 5,9-Disubstituted Pyrido[3′,2′:4,5]pyrrolo[1,2-c] pyrimidines
Nada Marquise
,
Tan Tai Nguyen
,
Floris Chevallier
,
Laurent Picot
,
Valérie Thiéry
et al.
Journal articles
hal-01248092v1
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Design and Microwave Synthesis of New (5Z) 5-Arylidene-2-thioxo-1,3-thiazolinidin-4-one and (5Z) 2-Amino-5-arylidene-1,3-thiazol-4(5H)-one as New Inhibitors of Protein Kinase DYRK1A
Khadidja Bourahla
,
Solène Guihéneuf
,
Emmanuelle Limanton
,
Ludovic Paquin
,
Rémy Le Guével
et al.
Journal articles
hal-03467664v1
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