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authIdHal_s : olivier-lozach
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A Practical Approach to New (5Z) 2-Alkylthio-5-arylmethylene- 1-methyl-1,5-dihydro-4H-imidazol-4-one Derivatives

Khadidja Bourahla , Ludovic Paquin , Olivier Lozach , Laurent Meijer , François Carreaux et al.
Molecules, 2011, 16, pp.7377-7390. ⟨10.3390/molecules16097377⟩
Journal articles hal-00870301v1

Dérivés d'imidazolones, procédé de préparation et applications biologiques.

J.P. Bazureau , François Carreaux , Stéven Renault , Laurent Meijer , Olivier Lozach et al.
Patent n° : FR 291 9608 (A1). 2009
Patents hal-00411458v1

Synthesis and preliminary biological evaluation of new derivatives of the marine alkaloid leucettamine B as kinase inhibitors.

Mansour Debdab , Stéven Renault , Olivier Lozach , Laurent Meijer , Ludovic Paquin et al.
European Journal of Medicinal Chemistry, 2010, 45 (2), pp.805-10. ⟨10.1016/j.ejmech.2009.10.009⟩
Journal articles istex hal-00869769v1

Leucettines, a class of potent inhibitors of cdc2-like kinases and dual specificity, tyrosine phosphorylation regulated kinases derived from the marine sponge leucettamine B: modulation of alternative pre-RNA splicing.

Mansour Debdab , François Carreaux , Steven Renault , Meera Soundararajan , Oleg Fedorov et al.
Journal of Medicinal Chemistry, 2011, 54 (12), pp.4172-86. ⟨10.1021/jm200274d⟩
Journal articles hal-00870007v1
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Substitution of unsaturated lipid chains by thioether-containing lipid chains in cationic amphiphiles: physicochemical consequences and application for gene delivery

Amal Bouraoui , Mathieu Berchel , Rosy Ghanem , Véronique Vie , Gilles Paboeuf et al.
Organic & Biomolecular Chemistry, 2019, 17 (14), pp.3609-3616. ⟨10.1039/c9ob00473d⟩
Journal articles hal-02088106v1

An expeditious, environment-friendly, and microwave-assisted synthesis of 5-isatinylidenerhodanine derivatives

Abdelmounaim Safer , Mustapha Rahmouni , François Carreaux , Ludovic Paquin , Olivier Lozach et al.
Chemical Papers, 2011, 65 (3), pp.332-337. ⟨10.2478/s11696-010-0104-9⟩
Journal articles hal-00869920v1
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Synthesis of new pyridazino[4,5-b]indol-4-ones and pyridazin-3(2H)-one analogs as DYRK1A inhibitors

Amélie Bruel , Romain Bénéteau , Mylène Chabanne , Olivier Lozach , Rémy Le Guevel et al.
Bioorganic and Medicinal Chemistry Letters, 2014, 24 (21), pp.5037 - 5040. ⟨10.1016/j.bmcl.2014.09.017⟩
Journal articles hal-01086026v1

Novel Tetrahydropyrido[1,2- a ]isoindolone Derivatives (Valmerins): Potent Cyclin-Dependent Kinase/Glycogen Synthase Kinase 3 Inhibitors with Antiproliferative Activities and Antitumor Effects in Human Tumor Xenografts

Rajâa Boulahjar , Aziz Ouach , Chiurato Matteo , Stéphane Bourg , Myriam Ravache et al.
Journal of Medicinal Chemistry, 2012, 55 (22), pp.9589-9606. ⟨10.1021/jm3008536⟩
Journal articles hal-02904751v1

Novel optimization of valmerins (tetrahydropyrido[1,2-a]isoindolones) as potent dual CDK5/GSK3 inhibitors

Aziz Ouach , Rajâa Boulahjar , Christine Vala , Stéphane Bourg , Pascal Bonnet et al.
European Journal of Medicinal Chemistry, 2016, 115, pp.311--325. ⟨10.1016/j.ejmech.2016.02.072⟩
Journal articles hal-01295635v1

An efficient method for the preparation of new analogs of Leucettamine B under solvent-free microwave irradiation.

Mansour Debdab , Stéven Renault , Samar Eid , Olivier Lozach , Laurent Meijer et al.
Heterocycles, 2009, pp.1191-1203
Journal articles hal-00411456v1

Novel Tetrahydropyrido[1,2-a]isoindolone Derivatives (Valmerins): Potent Cyclin-Dependent Kinase/Glycogen Synthase Kinase 3 Inhibitors with Antiproliferative Activities and Antitumor Effects in Human Tumor Xenografts

Rajâa Boulahjar , Aziz Ouach , Chiurato Matteo , Stéphane Bourg , Myriam Ravache et al.
Journal of Medicinal Chemistry, 2012, 55, pp.9589-9606
Journal articles hal-00785213v1

Synthesis and kinase inhibitory activity of novel substituted indigoids.

Anne Beauchard , Hélène Laborie , Hervé Rouillard , Olivier Lozach , Yoan Ferandin et al.
Bioorganic and Medicinal Chemistry, 2009, 17 (17), pp.6257-63. ⟨10.1016/j.bmc.2009.07.051⟩
Journal articles istex hal-00416031v1
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Azine and Diazine Functionalization Using 2,2,6,6-Tetramethylpiperidino-Based Lithium–Metal Combinations: Application to the Synthesis of 5,9-Disubstituted Pyrido[3′,2′:4,5]pyrrolo[1,2-c] pyrimidines

Nada Marquise , Tan Tai Nguyen , Floris Chevallier , Laurent Picot , Valérie Thiéry et al.
SYNLETT, 2015, 26 (20), pp.2811-2816. ⟨10.1055/s-0035-1560496⟩
Journal articles hal-01248092v1
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Design and Microwave Synthesis of New (5Z) 5-Arylidene-2-thioxo-1,3-thiazolinidin-4-one and (5Z) 2-Amino-5-arylidene-1,3-thiazol-4(5H)-one as New Inhibitors of Protein Kinase DYRK1A

Khadidja Bourahla , Solène Guihéneuf , Emmanuelle Limanton , Ludovic Paquin , Rémy Le Guével et al.
Pharmaceuticals, 2021, 14 (11), pp.1086-1117. ⟨10.3390/ph14111086⟩
Journal articles hal-03467664v1