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Acute cytotoxicity of the chemical carcinogen 2-acetylaminofluorene in cultured rat liver epithelial cells.
Lydie Sparfel
,
Maud Loewert
,
Laurence Huc
,
Léa Payen
,
André Guillouzo
et al.
Toxicology Letters, 2002, 129 (3), pp.245-54
Journal articles
hal-02673286v1
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TRAIL (TNF-related apoptosis-inducing ligand) induces necrosis-like cell death in tumor cells at acidic extracellular pH.
Olivier Meurette
,
Laurence Huc
,
Amelie Rebillard
,
Gwénaelle Le Moigne
,
Dominique Lagadic-Gossmann
et al.
Journal articles
hal-02683522v1
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Membrane remodeling, an early event in benzo[a]pyrene-induced apoptosis.
Xavier Tekpli
,
Mary Rissel
,
Laurence Huc
,
Daniel D. Catheline
,
Odile Sergent
et al.
Journal articles
istex
hal-00660136v1
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Kinetic analysis of the regulation of the Na+/H+ exchanger NHE-1 by osmotic shocks.
Jérôme Lacroix
,
Mallorie Poët
,
Laurence Huc
,
Vincent Morello
,
Nadir Djerbi
et al.
Journal articles
istex
hal-00674405v1
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Different mechanisms involved in apoptosis following exposure to benzo[a]pyrene in F258 and Hepa1c1c7 cells.
Jørn A. Holme
,
Morgane Gorria
,
Volker M. Arlt
,
Steinar Ovrebø
,
Anita Solhaug
et al.
Journal articles
hal-00690306v1
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Genome-Wide Transcriptional and Functional Analysis of Human T Lymphocytes Treated with Benzo[α]pyrene
Marie Liamin
,
Hélène Le Mentec
,
Bertrand Evrard
,
Laurence Huc
,
Frédéric Chalmel
et al.
Journal articles
hal-01940253v1
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Nrf2 and AhR in metabolic reprogramming after contaminant exposure
Sylvie Bortoli
,
Elisa Boutet-Robinet
,
Dominique Lagadic-Gossmann
,
Laurence Huc
Journal articles
hal-01699380v1
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Role for the ATPase inhibitory factor 1 in the environmental carcinogen-induced Warburg phenotype
Kévin Hardonnière
,
Morgane Fernier
,
Isabelle Gallais
,
Baharia Mograbi
,
Normand Podechard
et al.
Journal articles
hal-01518808v1
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The environmental carcinogen benzo[a]pyrene induces a Warburg-like metabolic reprogramming dependent on NHE1 and associated with cell survival
Kevin Hardonnière
,
Elise Saunier
,
Anthony Lemarié
,
Morgane Fernier
,
Isabelle Gallais
et al.
Journal articles
hal-01359569v1
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Benzo[a]pyrene-induced nitric oxide production acts as a survival signal targeting mitochondrial membrane potential
Kevin Hardonnière
,
Laurence Huc
,
Normand Podechard
,
Morgane Fernier
,
Xavier Tekpli
et al.
Journal articles
hal-01163757v1
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Disturbances in H dynamics during environmental carcinogenesis
Dominique Lagadic-Gossmann
,
Kévin Hardonnière
,
Baharia Mograbi
,
Odile Sergent
,
Laurence Huc
et al.
Journal articles
hal-02179386v1
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Transcriptomic analysis in zebrafish larvae identifies iron-dependent mitochondrial dysfunction as a possible key event of NAFLD progression induced by benzo[a]pyrene/ethanol co-exposure
Muhammad Imran
,
Frédéric Chalmel
,
Odile Sergent
,
Bertrand Evrard
,
Hélène Le Mentec
et al.
Journal articles
hal-03647402v1
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Identification of the couple GSK3α/c-Myc as a new regulator of hexokinase II in benzo[a]pyrene-induced apoptosis.
Béatrice Dendelé
,
Xavier Tekpli
,
Odile Sergent
,
Marie-Thérèse Dimanche-Boitrel
,
Jørn A. Holme
et al.
Journal articles
hal-00682104v1
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Characterization of human isogenic epithelial cell lines as a relevant tool to study colon carcinogenesis and interaction between genes and environment
Arnaud Tête
,
Liana C. Arnaud
,
Hélène Le Mentec
,
Isabelle Gallais
,
Nathalie Poupin
et al.
Society of Toxicology Annual Meeting (SOT 2022), Mar 2022, San Diego, United States. , 3579, pp.P204
Conference poster
hal-03637792v1
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Carcinogen-induced lipid membrane remodelling is essential for the NHE-1 activation involved in related apoptosis
Xavier Tekpli
,
Béatrice Dendelé
,
Laure Debure
,
Odile Sergent
,
Maryvonne Rissel
et al.
2nd International Meeting 2010 "Ion channels and Cancer", Mar 2010, Florence, Italy
Conference papers
hal-00675245v1
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Role for Na+/H+ Exchanger 1 (NHE1) in the Control of Apoptotic Pathways
Dominique Lagadic-Gossmann
,
Laurence Huc
,
Xavier Tekpli
C.O. Pickens. CELL APOPTOTIC SIGNALLING PATHWAYS, Nova Science Publishers, 222 p., 2006, 1-60021-507-6
Book sections
hal-00699966v1
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Hexokinase II: a key NHE1- and p53-regulated protein in benzo[a]pyrene-induced apoptosis.
Laurence Huc
,
Xavier Tekpli
,
Jørn A. Holme
,
Anita Solhaug
,
Morgane Gorria
et al.
The 12th World Congress on Advances in Oncology and 10th International Symposium on Molecular Medicine, Oct 2007, Crète, Greece. pp.S40
Conference papers
hal-00690394v1
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Implication des radeaux lipidiques dans l'apoptose induite par le benzo(a)pyrène
Xavier Tekpli
,
Mary Rissel
,
Laurence Huc
,
Daniel D. Catheline
,
Morgane Gorria
et al.
Journée OUEST-genopole. Lipides, lipidomique et stress oxydant, Apr 2008, Nantes, France
Conference papers
hal-00675819v1
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Protective effect of monosialoganglioside GM1 against chemically induced apoptosis through targeting of mitochondrial function and iron transport.
Morgane Gorria
,
Laurence Huc
,
Odile Sergent
,
Amélie Rébillard
,
François Gaboriau
et al.
Journal articles
hal-00699820v1
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Role for NHE1 in chemically-induced apoptosis In: Proton Homeostasis in Tumorigenesis and cell death processes
Laurence Huc
,
Xavier Tekpli
,
Amélie Rébillard
,
Marie-Thérèse Dimanche-Boitrel
,
Dominique Lagadic-Gossmann
et al.
Dominique Lagadic-Gossmann. Proton Homeostasis in Tumorigenesis and Cell Death, Research Signpost, pp. 65-81, 2011, 978-81-308-0429-3
Book sections
hal-00682523v1
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Characterization of human isogenic epithelial cell lines as a relevant tool to study colon carcinogenesis and interaction between genes and environment
Arnaud Tête
,
Liana C. Arnaud
,
Hélène Le Mentec
,
Isabelle Gallais
,
Noémie Tournadre
et al.
Congrès Annuel de la Société Française de Biochimie et Biologie Moléculaire, Jul 2021, Paris, France
Conference poster
hal-03279912v1
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Ahr-dependent lipid membrane remodelling: an early step facilitating benzo[a]pyrene-induced apoptosis
Jørn A. Holme
,
Xavier Tekpli
,
Béatrice Dendelé
,
Laure Debure
,
Odile Sergent
et al.
49th annual meeting of Society of Toxicology and ToxExpo, Mar 2010, Salt Lake City, United States
Conference papers
hal-00675239v1
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Environmental carcinogenesis and pH homeostasis: Not only a matter of dysregulated metabolism
Kévin Hardonniere
,
Laurence Huc
,
Odile Sergent
,
Jørn A Holme
,
Dominique Lagadic-Gossmann
et al.
Journal articles
hal-01531077v1
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The acidic extracellular pH : origin, role in tumorigenesis and cancer therapy
Marie-Thérèse Dimanche-Boitrel
,
Olivier Meurette
,
Sandrine Jouan-Lanhouet
,
Amélie Rébillard
,
Laurence Huc
et al.
Dominique Lagadic-Gossmann. Proton homeostasis in tumorigenesis and cell death processes, RESEARCH SIGNPOST, pp. 105-118, 2011, 978-81-308-0429-3
Book sections
hal-00682514v1
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Inhibition of carcinogen-bioactivating cytochrome P450 1 isoforms by amiloride derivatives.
Lydie Sparfel
,
Laurence Huc
,
Marc Le Vée
,
Mireille Desille
,
Dominique Lagadic-Gossmann
et al.
Journal articles
hal-02681620v1
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TRAIL induces receptor-interacting protein 1-dependent and caspase-dependent necrosis-like cell death under acidic extracellular conditions.
Olivier Meurette
,
Amélie Rébillard
,
Laurence Huc
,
Gwenaëlle Le Moigne
,
Delphine Merino
et al.
Journal articles
hal-00690349v1
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Identification of Na+/H+ exchange as a new target for toxic polycyclic aromatic hydrocarbons.
Laurence Huc
,
Lydie Sparfel
,
Mary Rissel
,
Marie-Thérèse Dimanche-Boitre
,
André Guillouzo
et al.
Journal articles
hal-02678074v1
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Apoptotic mitochondrial dysfunction induced by benzo(a)pyrene in liver epithelial cells: role of p53 and pHi changes.
Laurence Huc
,
David Gilot
,
Claire Gardyn
,
Mary Rissel
,
Marie-Thérèse Dimanche-Boitrel
et al.
Annals of the New York Academy of Sciences, 2003, 1010, pp.167-70
Journal articles
hal-02681880v1
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Membrane fluidity changes are associated with benzo[a]pyrene-induced apoptosis in F258 cells: protection by exogenous cholesterol.
Morgane Gorria
,
Xavier Tekpli
,
Odile Sergent
,
Laurence Huc
,
François Gaboriau
et al.
Journal articles
istex
hal-00699948v1
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A new lactoferrin- and iron-dependent lysosomal death pathway is induced by benzo[a]pyrene in hepatic epithelial cells.
Morgane Gorria
,
Xavier Tekpli
,
Mary Rissel
,
Odile Sergent
,
Laurence Huc
et al.
Journal articles
hal-00674390v1
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