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authIdHal_s : eric-le-ferrec

NPC1 repression contributes to lipid accumulation in human macrophages exposed to environmental aryl hydrocarbons.

Normand Podechard , E. Le Ferrec , Amélie Rébillard , Olivier Fardel , Valérie Lecureur et al.
Cardiovascular Research, 2009, 82 (2), pp.361-70. ⟨10.1093/cvr/cvp007⟩
Journal articles hal-00673351v1

Dioxin-mediated up-regulation of aryl hydrocarbon receptor target genes is dependent on the calcium/calmodulin/CaMKIalpha pathway.

Patricia Monteiro , David Gilot , E. Le Ferrec , Claudine Rauch , Dominique Lagadic-Gossmann et al.
Molecular Pharmacology, 2008, 73 (3), pp.769-77. ⟨10.1124/mol.107.043125⟩
Journal articles hal-00696176v1

Aryl hydrocarbon receptor-independent up-regulation of intracellular calcium concentration by environmental polycyclic aromatic hydrocarbons in human endothelial HMEC-1 cells.

Abdullah Mayati , Eric Le Ferrec , Dominique Lagadic-Gossmann , Olivier Fardel
Environmental Toxicology, 2011, 27 (9), pp.556-562. ⟨10.1002/tox.20675⟩
Journal articles istex hal-00680889v1
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Microalgal carotenoids and phytosterols regulate biochemical mechanisms involved in human health and disease prevention

Manon Le Goff , E. Le Ferrec , Claire Mayer , Virginie Mimouni , Dominique Lagadic-Gossmann et al.
Biochimie, 2019, 167, pp.106-118. ⟨10.1016/j.biochi.2019.09.012⟩
Journal articles hal-02302332v1
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Genome-Wide Transcriptional and Functional Analysis of Human T Lymphocytes Treated with Benzo[α]pyrene

Marie Liamin , Hélène Le Mentec , Bertrand Evrard , Laurence Huc , Frédéric Chalmel et al.
International Journal of Molecular Sciences, 2018, 19 (11), pp.E3626. ⟨10.3390/ijms19113626⟩
Journal articles hal-01940253v1
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Role for the ATPase inhibitory factor 1 in the environmental carcinogen-induced Warburg phenotype

Kévin Hardonnière , Morgane Fernier , Isabelle Gallais , Baharia Mograbi , Normand Podechard et al.
Scientific Reports, 2017, 7 (1), pp.195. ⟨10.1038/s41598-017-00269-7⟩
Journal articles hal-01518808v1

Le récepteur Ah et le facteur de transcription c-maf sont indispensables à l'induction de l'intégrine ß7 par le benzo(a)pyrène

P. Monteiro , David Gilot , Monique N'Diaye , Valérie Lecureur , E. Le Ferrec et al.
Conférence à l'institut Curie, Jun 2006, Orsay, France
Conference papers hal-00699680v1

Interleukin-8 induction by the environmental contaminant benzo(a)pyrene is aryl hydrocarbon receptor-dependent and leads to lung inflammation.

Normand Podechard , Valérie Lecureur , E. Le Ferrec , Isabelle Guenon , Lydie Sparfel et al.
Toxicology Letters, 2008, 177 (2), pp.130-7. ⟨10.1016/j.toxlet.2008.01.006⟩
Journal articles istex hal-00673238v1
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Benzo[a]pyrene-induced DNA damage associated with mutagenesis in primary human activated T lymphocytes

Marie Liamin , Elisa Boutet-Robinet , Emilien L. Jamin , Morgane Fernier , Laure Khoury et al.
Biochemical Pharmacology, 2017, 137, pp.113-124. ⟨10.1016/j.bcp.2017.04.025⟩
Journal articles hal-01560145v1

Polycyclic aromatic hydrocarbons can trigger a hepatocyte release of cytotoxic extracellular vesicles

Nettie van Meteren , Martine Chevanne , Isabelle Gallais , Fabienne Gauffre , Soizic Chevance et al.
Journal of Hepatology, 2019, 70 (1), pp.E811. ⟨10.1016/S0618-8278(19)31622-6⟩
Journal articles hal-02149788v1

TNFalpha- and NF-kappaB-dependent induction of the chemokine CCL1 in human macrophages exposed to the atherogenic lipoprotein(a).

Monique N'Diaye , E. Le Ferrec , Florian Kronenberg , Hans Dieplinger , Marc Le Vee et al.
Life Sciences, 2009, 84 (13-14), pp.451-7. ⟨10.1016/j.lfs.2009.01.012⟩
Journal articles istex hal-00673344v1

Identification de nouvelles cibles moléculaires des hydrocarbures aromatiques polycycliques : implications potentielles pour l'analyse de risque

Olivier Fardel , David Gilot , Valérie Lecureur , E. Le Ferrec , Marc Le Vee et al.
Journées Scientifiques de l'AFSSET, Feb 2006, Maisons-Alfort, France
Conference papers hal-00699806v1

Aryl hydrocarbon receptor- and c-maf-dependent induction of the integrin beta7 by the environmental contaminant benzo(a)pyrene

P. Monteiro , David Gilot , Monique N'Diaye , Valérie Lecureur , E. Le Ferrec et al.
20ième Anniversaire de la Société de Pharmaco-Toxicologie Cellulaire (SPTC), Mar 2006, Paris, France
Conference papers hal-00699763v1
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Protective Action of Ostreococcus tauri and Phaeodactylum tricornutum Extracts towards Benzo[a]Pyrene-Induced Cytotoxicity in Endothelial Cells

Manon Le Goff , Antoine Delbrut , Marie Quinton , Rémi Pradelles , Maelle Bescher et al.
Marine drugs, 2019, 18 (1), ⟨10.3390/md18010003⟩
Journal articles hal-02441226v1
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G-protein coupled receptors (GPCR) and environmental exposure. Consequences for cell metabolism using the β-adrenoceptors as example

E. Le Ferrec , Johan Øvrevik
Current Opinion in Toxicology, 2018, 8, pp.14-19. ⟨10.1016/j.cotox.2017.11.012⟩
Journal articles hal-01699375v1
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Lipophilic components of diesel exhaust particles induce pro-inflammatory responses in human endothelial cells through AhR dependent pathway(s)

Bendik C. Brinchmann , Tonje Skuland , Mia H. Rambol , Krisztina Szoke , Jan E. Brinchmann et al.
Particle and Fibre Toxicology, 2018, 15 (1), pp.21. ⟨10.1186/s12989-018-0257-1⟩
Journal articles hal-01863051v1
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Extracellular vesicles released by polycyclic aromatic hydrocarbons-treated hepatocytes trigger oxidative stress in recipient hepatocytes by delivering iron

Nettie van Meteren , Dominique Lagadic-Gossmann , Normand Podechard , Dimitri Gobart , Isabelle Gallais et al.
Free Radical Biology and Medicine, 2020, 160, pp.246-262. ⟨10.1016/j.freeradbiomed.2020.08.001⟩
Journal articles hal-02930146v1
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Small RNA-sequencing reveals the involvement of microRNA-132 in benzo[a]pyrene-induced toxicity in primary human blood cells

Rima Souki , Jérémy Amosse , Valentine Genet , Morgane Le Gall , Benjamin Saintpierre et al.
Environmental Pollution, 2023, 328, pp.121653. ⟨10.1016/j.envpol.2023.121653⟩
Journal articles hal-04099863v1

Toxicologie predictive: les voies du futur

Ph Detilleux , L Vallier , C Legallais , E Leclerc , M Prot J et al.
Congrès de la SPTC - Société de Pharmaco-Toxicologie Cellulaire, May 2010, Paris, France
Conference papers hal-01122677v1

Extracellular vesicles are involved in polycyclic aromatic hydrocarbon hepatotoxicity

N. van Meteren , D. Gobart , I. Gallais , E. Le Ferrec , D. Lagadic-Gossmann et al.
Toxicology Letters, 2019, 314, pp.S187-S188
Journal articles hal-02303536v1
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Calcium signaling and β2-adrenergic receptors regulate 1-nitropyrene induced CXCL8 responses in BEAS-2B cells.

Abdullah Mayati , E. Le Ferrec , Jørn A Holme , Olivier Fardel , Dominique Lagadic-Gossmann et al.
Toxicology in Vitro, 2014, 28 (6), pp.1153-7. ⟨10.1016/j.tiv.2014.05.012⟩
Journal articles hal-01058607v1

Polycyclic aromatic hydrocarbons can trigger hepatocyte release of extracellular vesicles by various mechanisms of action depending on their affinity for the aryl hydrocarbon receptor

Nettie van Meteren , Dominique Lagadic-Gossmann , Martine Chevanne , Isabelle Gallais , Dimitri Gobart et al.
Toxicological Sciences, 2019, 171 (2), pp.443-462. ⟨10.1093/toxsci/kfz157⟩
Journal articles hal-02280777v1

Analysis of drug transporter expression in human intestinal Caco-2 cells by real-time PCR.

Nathalie Maubon , Marc Le Vee , Lina Fossati , Mathilde Audry , E. Le Ferrec et al.
Fundamental & Clinical Pharmacology, 2007, 21 (6), pp.659-63. ⟨10.1111/j.1472-8206.2007.00550.x⟩
Journal articles istex hal-00690294v1
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Benzo(a) pyrene triggers desensitization of beta 2-adrenergic pathway

Abdullah Mayati , Normand Podechard , Manuelle Rineau , Lydie Sparfel , Dominique Lagadic-Gossmann et al.
Scientific Reports, 2017, 7 (1), pp.3262. ⟨10.1038/s41598-017-03646-4⟩
Journal articles hal-01560151v1
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Lipophilic Chemicals from Diesel Exhaust Particles Trigger Calcium Response in Human Endothelial Cells via Aryl Hydrocarbon Receptor Non-Genomic Signalling

Bendik C Brinchmann , E. Le Ferrec , Normand Podechard , Dominique Lagadic-Gossmann , Kenji F Shoji et al.
International Journal of Molecular Sciences, 2018, 19 (5), pp.1429. ⟨10.3390/ijms19051429⟩
Journal articles hal-01795808v1
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PAHs increase the production of extracellular vesicles both in vitro in endothelial cells and in vivo in urines from rats

Manon Le Goff , Dominique Lagadic-Gossmann , Remi Latour , Normand Podechard , Nathalie Grova et al.
Environmental Pollution, 2019, 255, pp.113171. ⟨10.1016/j.envpol.2019.113171⟩
Journal articles hal-02302334v1

Inflammatory response to benzo(a)pyrene, a major environmental contaminant, in primary human macrophages

Normand Podechard , E. Le Ferrec , M. N'Diaye , Lydie Sparfel , David Gilot et al.
11ème Colloque Cytokines de la Société Française d'Immunologie, May 2009, Le Croisic, France
Conference papers hal-00674286v1

Induction of intracellular calcium concentration by environmental benzo(a)pyrene involves a β2-adrenergic receptor/adenylyl cyclase/Epac-1/inositol 1,4,5-trisphosphate pathway in endothelial cells.

Abdullah Mayati , Nicolas Levoin , Hervé Paris , Monique N'Diaye , Arnaud Courtois et al.
Journal of Biological Chemistry, 2012, 287 (6), pp.4041-52. ⟨10.1074/jbc.M111.319970⟩
Journal articles hal-00682497v1

Applications Using Caco-2 and TC7 Cells for Drug Metabolism Studies

Eric Le Ferrec , Olivier Fardel
Encyclopedia of Drug Metabolism and Interactions, John Wiley & Sons, 2011, ⟨10.1002/9780470921920.edm061⟩
Book sections hal-01117670v1

Aryl hydrocarbon receptor- and calcium-dependent induction of the chemokine CCL1 by the environmental contaminant benzo[a]pyrene.

Monique N'Diaye , E. Le Ferrec , Dominique Lagadic-Gossmann , Sébastien Corre , David Gilot et al.
Journal of Biological Chemistry, 2006, 281 (29), pp.19906-15. ⟨10.1074/jbc.M601192200⟩
Journal articles hal-00699622v1