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Structural and molecular bases to IRE1 activity modulation

Timothy Langlais , Diana Pelizzari-Raymundo , Sayyed Jalil Mahdizadeh , Nicolas Gouault , François Carreaux et al.
Biochemical Journal, 2021, 478 (15), pp.2953-2975. ⟨10.1042/BCJ20200919⟩
Journal articles hal-03331317v1

Leucettines, a class of potent inhibitors of cdc2-like kinases and dual specificity, tyrosine phosphorylation regulated kinases derived from the marine sponge leucettamine B: modulation of alternative pre-RNA splicing.

Mansour Debdab , François Carreaux , Steven Renault , Meera Soundararajan , Oleg Fedorov et al.
Journal of Medicinal Chemistry, 2011, 54 (12), pp.4172-86. ⟨10.1021/jm200274d⟩
Journal articles hal-00870007v1

An efficient approach to dispacamide A and its derivatives.

Solène Guihéneuf , Ludovic Paquin , François Carreaux , Emilie Durieu , Laurent Meijer et al.
Organic & Biomolecular Chemistry, 2012, 10 (5), pp.978-87. ⟨10.1039/c1ob06161e⟩
Journal articles hal-00870469v1

Alkenylboron Cross-Coupling

Bertrand Carboni , François Carreaux
Mats Larhed, John P. Wolfe, G. Molander. Science of Synthesis, Georg Thieme Verlag, pp.265-322, 2012
Book sections hal-00873122v1

Boron- and silicon-substituted [3]-1-heterodendralenes as versatile building blocks for the rapid construction of polycyclic architectures.

Fabien Tripoteau , Tristan Verdelet , Alain Hercouet , François Carreaux , Bertrand Carboni et al.
Chemistry - A European Journal, 2011, 17 (49), pp.13670-13675. ⟨10.1002/chem.201101624⟩
Journal articles istex hal-00869895v1
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BINOL derivatives-catalysed enantioselective allylboration of isatins: application to the synthesis of (R)-chimonamidine

Julien Braire , Vincent Dorcet , Joëlle Vidal , Claudia Lalli , François Carreaux et al.
Organic & Biomolecular Chemistry, 2020, 18 (31), pp.6042-6046. ⟨10.1039/d0ob01386b⟩
Journal articles hal-02928635v1

Iridium-Catalyzed Allylic Amination Route to α-Aminoboronates: Illustration of the Decisive Role of Boron Substituents.

Sabrina Touchet , François Carreaux , Gary A. Molander , Bertrand Carboni , Alexandre Bouillon et al.
Advanced Synthesis and Catalysis, 2011, 353 (18), pp.3391-3396. ⟨10.1002/adsc.201100407⟩
Journal articles hal-00869890v1

Solid-phase reactions of resin-supported boronic acids

François Carreaux , Bertrand Carboni , Hervé Deleuze , Christelle Pourbaix-L'Ebraly
Peter J. H. Scott. Solid-Phase Organic Syntheses, Wiley, pp.107-118, 2012, ⟨10.1002/9781118336953.ch12⟩
Book sections hal-00873126v1
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A Practical Approach to New (5Z) 2-Alkylthio-5-arylmethylene- 1-methyl-1,5-dihydro-4H-imidazol-4-one Derivatives

Khadidja Bourahla , Ludovic Paquin , Olivier Lozach , Laurent Meijer , François Carreaux et al.
Molecules, 2011, 16, pp.7377-7390. ⟨10.3390/molecules16097377⟩
Journal articles hal-00870301v1

Synthesis of alkenyl boronates from allyl-substituted aromatics using an olefin cross-metathesis protocol.

Rémy Hemelaere , François Carreaux , Bertrand Carboni
Journal of Organic Chemistry, 2013, 78 (13), pp.6786-92. ⟨10.1021/jo400872x⟩
Journal articles hal-00861076v1

Synthesis and preliminary biological evaluation of new derivatives of the marine alkaloid leucettamine B as kinase inhibitors.

Mansour Debdab , Stéven Renault , Olivier Lozach , Laurent Meijer , Ludovic Paquin et al.
European Journal of Medicinal Chemistry, 2010, 45 (2), pp.805-10. ⟨10.1016/j.ejmech.2009.10.009⟩
Journal articles istex hal-00869769v1

Aminoboronic acids and esters: from synthetic challenges to the discovery of unique classes of enzyme inhibitors.

Sabrina Touchet , François Carreaux , Bertrand Carboni , Alexandre Bouillon , Jean-Luc Boucher et al.
Chemical Society Reviews, 2011, 40 (7), pp.3895-914. ⟨10.1039/c0cs00154f⟩
Journal articles hal-00869909v1

Selectivity, cocrystal structures, and neuroprotective properties of leucettines, a family of protein kinase inhibitors derived from the marine sponge alkaloid leucettamine B.

Tania Tahtouh , Jonathan M. Elkins , Panagis Filippakopoulos , Meera Soundararajan , Guillaume Burgy et al.
Journal of Medicinal Chemistry, 2012, 55 (21), pp.9312-30. ⟨10.1021/jm301034u⟩
Journal articles hal-00870472v1

A new access to the 6,8-dioxabicyclo[3.2.1]octane ring system using a three-component reaction : enantioselective synthesis of (+)-iso-exo-brevicomin

Asmae Bouziane , Thomas Régnier , François Carreaux , Bertrand Carboni , Christian Bruneau et al.
SYNLETT, 2010, 2010 (2), pp.207-210. ⟨10.1055/s-0029-1218561⟩
Journal articles hal-00492573v1

An expeditious, environment-friendly, and microwave-assisted synthesis of 5-isatinylidenerhodanine derivatives

Abdelmounaim Safer , Mustapha Rahmouni , François Carreaux , Ludovic Paquin , Olivier Lozach et al.
Chemical Papers, 2011, 65 (3), pp.332-337. ⟨10.2478/s11696-010-0104-9⟩
Journal articles hal-00869920v1
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Boron-substituted 1,3-dienes and heterodienes as key elements in multicomponent processes

Ludovic Eberlin , Fabien Tripoteau , François Carreaux , Andrew Whiting , Bertrand Carboni et al.
Beilstein Journal of Organic Chemistry, 2014, 10, pp.237-250. ⟨10.3762/bjoc.10.19⟩
Journal articles hal-00955602v1

Chemical synthesis and biological validation of immobilized protein kinase inhibitory Leucettines.

Guillaume Burgy , Tania Tahtouh , Emilie Durieu , Béatrice Foll-Josselin , Emmanuelle Limanton et al.
European Journal of Medicinal Chemistry, 2013, 62, pp.728-37. ⟨10.1016/j.ejmech.2013.01.035⟩
Journal articles hal-00822733v1

Leucettines, a family of pharmacological inhibitors of DYRKs & CLKs kinases derived from the marine sponge Leucettamine B

T. Tahtouh , O. Fedorov , O. Lozach , François Carreaux , Jean-Pierre Bazureau et al.
Planta Medica, 2012, 78, pp.PD1. ⟨10.1055/s-0032-1320359⟩
Journal articles hal-00870776v1
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Microwave-assisted synthesis of new 2-aryl and 2-alkylimidazolones and evaluation of their in vitro anticancer activity and their in vivo toxicity on zebrafish embryos

Samar Bou Zeid , Aline Hamade , Fadia Najjar , François Carreaux , Samar Eid et al.
Chemical Papers, 2021, 75 (6), pp.2549-2560. ⟨10.1007/s11696-020-01502-w⟩
Journal articles hal-03156159v1

An Efficient Solvent-Free Microwave-Assisted Synthesis of Cinnamamides by Amidation Reaction Using Phenylboronic Acid/Lewis Base Co-catalytic System

Khadidja Khaldoun , Abdelmounaim Safer , Salima Saidi-Besbes , Bertrand Carboni , Remy Le Guevel et al.
Synthesis: Journal of Synthetic Organic Chemistry, 2019, 51 (20), pp.3891-3900. ⟨10.1055/s-0039-1690132⟩
Journal articles hal-02359980v1

Catalytic Enantioselective Allylboration and Related Reactions of Isatins Promoted by Chiral BINOLs: Scope and Mechanistic Studies

Julien Braire , Aurélie Macé , Rania Zaier , Marie Cordier , Joëlle Vidal et al.
Journal of Organic Chemistry, 2023, 88 (3), pp.1469-1492. ⟨10.1021/acs.joc.2c02476⟩
Journal articles hal-03971612v1

[3,3]-Sigmatropic rearrangement of boronated allylcyanates: a new route to α-aminoboronate derivatives and trisubstituted tetrahydrofurans.

Sabrina Touchet , Aurélie Macé , Thierry Roisnel , François Carreaux , Alexandre Bouillon et al.
Organic Letters, 2013, 15 (11), pp.2712-5. ⟨10.1021/ol401016x⟩
Journal articles hal-00861083v1
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Stereodivergent approach in the protected glycal synthesis of L-vancosamine, L-saccharosamine, L-daunosamine and L-ristosamine involving a ring-closing metathesis step

Pierre-Antoine Nocquet , Aurélie Macé , Frédéric Legros , Jacques Lebreton , Gilles Dujardin et al.
Beilstein Journal of Organic Chemistry, 2018, 14, pp.2949-2955. ⟨10.3762/bjoc.14.274⟩
Journal articles hal-01973903v1
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1,3-Dioxa-[3,3]-sigmatropic Oxo-Rearrangement of Substituted Allylic Carbamates: Scope and Mechanistic Studies

Maddalen Agirre , S. Henrion , Ivan Rivilla , José Miranda , Fernando Cossío et al.
Journal of Organic Chemistry, 2018, 83 (24), pp.14861-14881. ⟨10.1021/acs.joc.8b01320⟩
Journal articles hal-01954300v1