|
|
Acute cytotoxicity of the chemical carcinogen 2-acetylaminofluorene in cultured rat liver epithelial cells.
Lydie Sparfel
,
Maud Loewert
,
Laurence Huc
,
Léa Payen
,
André Guillouzo
et al.
Toxicology Letters, 2002, 129 (3), pp.245-54
Journal articles
hal-02673286v1
|
Share
Gmail
Facebook
Twitter
LinkedIn
More
|
|
|
Identification of genes regulated by the environmental contaminant benzo(a)pyrene in primary human macrophages
Lydie Sparfel
,
Marie-Laure Pinel-Marie
,
Magali Boize
,
Serge Koscielny
,
Sophie Desmots
et al.
Annual Meeting 100th American Association for Cancer Research, Apr 2009, Denver, United States
Conference papers
hal-00673940v1
|
Share
Gmail
Facebook
Twitter
LinkedIn
More
|
|
|
AhR-dependent induction of the NADPH oxidase component p47phox by benzo(a)pyrene in human macrophages
Marie-Laure Pinel-Marie
,
Lydie Sparfel
,
Sophie Desmots
,
Olivier Fardel
Annual Meeting 100th American Association for Cancer Research, Apr 2009, Denver, United States
Conference papers
hal-00674272v1
|
Share
Gmail
Facebook
Twitter
LinkedIn
More
|
|
|
Mechanisms involved in the death of steatotic WIF-B9 hepatocytes co-exposed to benzo[a]pyrene and ethanol a possible key role for xenobiotic metabolism and nitric oxide
Arnaud Tête
,
Isabelle Gallais
,
Muhammad Imran
,
Martine Chevanne
,
Marie Liamin
et al.
Journal articles
hal-01888877v1
|
Share
Gmail
Facebook
Twitter
LinkedIn
More
|
|
|
Genome-Wide Transcriptional and Functional Analysis of Human T Lymphocytes Treated with Benzo[α]pyrene
Marie Liamin
,
Hélène Le Mentec
,
Bertrand Evrard
,
Laurence Huc
,
Frédéric Chalmel
et al.
Journal articles
hal-01940253v1
|
Share
Gmail
Facebook
Twitter
LinkedIn
More
|
|
|
Inhibition of carcinogen-bioactivating cytochrome P450 1 isoforms by amiloride derivatives.
Lydie Sparfel
,
Laurence Huc
,
Marc Le Vée
,
Mireille Desille
,
Dominique Lagadic-Gossmann
et al.
Journal articles
hal-02681620v1
|
Share
Gmail
Facebook
Twitter
LinkedIn
More
|
|
|
Predicting in vivo gene expression in macrophages after exposure to benzo(a)pyrene based on in vitro assays and toxicokinetic/toxicodynamic models
Alexandre R.R. Pery
,
Céline Brochot
,
Sophie Desmots
,
Magali Boize
,
Lydie Sparfel
et al.
Journal articles
hal-00873317v1
|
Share
Gmail
Facebook
Twitter
LinkedIn
More
|
|
|
Identification de nouvelles cibles moléculaires des hydrocarbures aromatiques polycycliques : implications potentielles pour l'analyse de risque
Olivier Fardel
,
David Gilot
,
Valérie Lecureur
,
E. Le Ferrec
,
Marc Le Vee
et al.
Journées Scientifiques de l'AFSSET, Feb 2006, Maisons-Alfort, France
Conference papers
hal-00699806v1
|
Share
Gmail
Facebook
Twitter
LinkedIn
More
|
|
|
Nrf2 expression and activity in human T lymphocytes: stimulation by T cell receptor activation and priming by inorganic arsenic and tert-butylhydroquinone.
Claudie Morzadec
,
Mélinda Macoch
,
Lydie Sparfel
,
Saadia Kerdine-Römer
,
Olivier Fardel
et al.
Journal articles
hal-01018643v1
|
Share
Gmail
Facebook
Twitter
LinkedIn
More
|
|
|
Identification of Na+/H+ exchange as a new target for toxic polycyclic aromatic hydrocarbons.
Laurence Huc
,
Lydie Sparfel
,
Mary Rissel
,
Marie-Thérèse Dimanche-Boitre
,
André Guillouzo
et al.
Journal articles
hal-02678074v1
|
Share
Gmail
Facebook
Twitter
LinkedIn
More
|
|
|
Identification d'une nouvelle cible moléculaire des hydrocarbures aromatiques dans les macrophages humains en culture primaire : le gène NCF1 codant pour la protéine p47phox et potentialisation de la production d'espèces réactives de l'oxygène en réponse au PMA
Marie-Laure Pinel-Marie
,
Lydie Sparfel
,
Olivier Fardel
Journée Ouest Génopole 'Stress Oxydant', Dec 2008, Rennes, France
Conference papers
hal-00674279v1
|
Share
Gmail
Facebook
Twitter
LinkedIn
More
|
|
|
Transcriptional signature of human macrophages exposed to the environmental contaminant benzo(a)pyrene.
Lydie Sparfel
,
Marie-Laure Pinel-Marie
,
Magali Boize
,
Serge Koscielny
,
Sophie Desmots
et al.
Journal articles
hal-00657921v1
|
Share
Gmail
Facebook
Twitter
LinkedIn
More
|
|
|
The aryl hydrocarbon receptor is functionally upregulated early in the course of human T-cell activation
Laurie Prigent
,
Marc Robineau
,
Stéphane Jouneau
,
Claudie Morzadec
,
Laetitia Louarn
et al.
Journal articles
hal-01063944v1
|
Share
Gmail
Facebook
Twitter
LinkedIn
More
|
|
|
Interleukin-8 induction by the environmental contaminant benzo(a)pyrene is aryl hydrocarbon receptor-dependent and leads to lung inflammation.
Normand Podechard
,
Valérie Lecureur
,
E. Le Ferrec
,
Isabelle Guenon
,
Lydie Sparfel
et al.
Journal articles
istex
hal-00673238v1
|
Share
Gmail
Facebook
Twitter
LinkedIn
More
|
|
|
Potent inhibition of carcinogen-bioactivating cytochrome P450 1B1 by the p53 inhibitor pifithrin a
Lydie Sparfel
P53 strategies for fighting cancer, Nov 2008, Londres, United Kingdom
Conference papers
hal-00673415v1
|
Share
Gmail
Facebook
Twitter
LinkedIn
More
|
|
|
Exposition de macrophages humains aux hydrocarbures aromatiques polycycliques : identification de nouvelles cibles moléculaires
Lydie Sparfel
,
Marie-Laure Pinel-Marie
,
Magali Boize
,
Serge Koscielny
,
Alexandre R.R. Pery
et al.
Journée Ouest Génopole 'Approche du stress par approche transcriptomique', Sep 2008, Brest, France
Conference papers
hal-00674276v1
|
Share
Gmail
Facebook
Twitter
LinkedIn
More
|
|
|
Benzo[a]pyrene-induced DNA damage associated with mutagenesis in primary human activated T lymphocytes
Marie Liamin
,
Elisa Boutet-Robinet
,
Emilien L. Jamin
,
Morgane Fernier
,
Laure Khoury
et al.
Journal articles
hal-01560145v1
|
Share
Gmail
Facebook
Twitter
LinkedIn
More
|
|
|
Inorganic arsenic represses interleukin-17A expression in human activated Th17 lymphocytes.
Claudie Morzadec
,
Mélinda Macoch
,
Marc Robineau
,
Lydie Sparfel
,
Olivier Fardel
et al.
Journal articles
inserm-00872871v1
|
Share
Gmail
Facebook
Twitter
LinkedIn
More
|
|
|
Aryl hydrocarbon receptor-dependent induction of the IgA receptor FcalphaRI by the environmental contaminant benzo(a)pyrene in human macrophages
Lydie Sparfel
,
Marie-Laure Pinel-Marie
,
L. Louarn
,
Sophie Desmots
,
Olivier Fardel
et al.
47. European Congress of Toxicology (EUROTOX 2011), Aug 2011, Paris, France
Conference papers
ineris-00970856v1
|
Share
Gmail
Facebook
Twitter
LinkedIn
More
|
|
|
Apports des approches " omiques " pour modéliser la cinétique et les effets de xénobiotiques chez l'homme
Alexandre R.R. Pery
,
Céline Brochot
,
M. Dumas
,
Magali Boize
,
Sophie Desmots
et al.
Colloque ARET, Jun 2010, Paris, France
Conference papers
hal-00674296v1
|
Share
Gmail
Facebook
Twitter
LinkedIn
More
|
|
|
Intérêt potentiel de cibles géniques des hydrocarbures aromatiques polycycliques en tant que biomarqueurs d'exposition
Lydie Sparfel
,
Marie-Laure Pinel-Marie
,
Serge Koscielny
,
Sophie Desmots
,
Alexandre R.R. Pery
et al.
Environnement, Risques & Santé, 2011, 10 (3), pp.195-199
Journal articles
hal-00682429v1
|
Share
Gmail
Facebook
Twitter
LinkedIn
More
|
|
|
Identification de nouveaux gènes cibles des hydrocarbures aromatiques polycycliques dans les macrophages humains en culture primaire par une approche transcriptomique
Lydie Sparfel
,
Marie-Laure Pinel-Marie
,
Magali Boize
,
Serge Koscielny
,
Sophie Desmots
et al.
Congrès de la Société de Pharmaco-Toxicologie Cellulaire " Toxicologie prédictive : les voies du futur ", May 2010, Paris, France
Conference papers
hal-00674292v1
|
Share
Gmail
Facebook
Twitter
LinkedIn
More
|
|
|
Global effects of inorganic arsenic on gene expression profile in human macrophages.
Emilie Bourdonnay
,
Claudie Morzadec
,
Lydie Sparfel
,
Marie-Dominique Galibert
,
Stéphane Jouneau
et al.
Journal articles
istex
inserm-00355570v1
|
Share
Gmail
Facebook
Twitter
LinkedIn
More
|
|
|
Potent inhibition of carcinogen-bioactivating cytochrome P450 1B1 by the p53 inhibitor pifithrin alpha.
Lydie Sparfel
,
Julien van Grevenynghe
,
Marc Le Vee
,
Caroline Aninat
,
Olivier Fardel
et al.
Journal articles
hal-00699629v1
|
Share
Gmail
Facebook
Twitter
LinkedIn
More
|
|
|
Aryl hydrocarbon receptor-dependent induction of the NADPH oxidase subunit NCF1/p47 phox expression leading to priming of human macrophage oxidative burst.
Marie-Laure Pinel-Marie
,
Lydie Sparfel
,
Sophie Desmots
,
Olivier Fardel
Journal articles
istex
hal-00673349v1
|
Share
Gmail
Facebook
Twitter
LinkedIn
More
|
|
|
Benzo(a) pyrene triggers desensitization of beta 2-adrenergic pathway
Abdullah Mayati
,
Normand Podechard
,
Manuelle Rineau
,
Lydie Sparfel
,
Dominique Lagadic-Gossmann
et al.
Journal articles
hal-01560151v1
|
Share
Gmail
Facebook
Twitter
LinkedIn
More
|
|
|
Inflammatory response to benzo(a)pyrene, a major environmental contaminant, in primary human macrophages
Normand Podechard
,
E. Le Ferrec
,
M. N'Diaye
,
Lydie Sparfel
,
David Gilot
et al.
11ème Colloque Cytokines de la Société Française d'Immunologie, May 2009, Le Croisic, France
Conference papers
hal-00674286v1
|
Share
Gmail
Facebook
Twitter
LinkedIn
More
|
|
|
MEHP/ethanol co-exposure favors the death of steatotic hepatocytes, possibly through CYP4A and ADH involvement
Arnaud Tête
,
Isabelle Gallais
,
Muhammad Imran
,
Louis Legoff
,
Corinne Martin-Chouly
et al.
Journal articles
hal-02978021v1
|
Share
Gmail
Facebook
Twitter
LinkedIn
More
|