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MONOCYTIC MYELOID-DERIVED SUPPRESSOR CELL EXPANSION AFTER CARDIAC SURGERY WITH CARDIOPULMONARY BYPASS INDUCES LYMPHOCYTE DYSFUNCTION

Mathieu Lesouhaitier , Fabrice Uhel , Murielle Grégoire , Arnaud Gacouin , Aurelien Frerou et al.
Shock, 2022, 58 (6), pp.476-483. ⟨10.1097/SHK.0000000000002007⟩
Journal articles hal-03967873v1

DC-SIGN expressing macrophages trigger activation of mannosylated IgM B-cell receptor in follicular lymphoma

Rada Amin , Frédéric Mourcin , Fabrice Uhel , Céline Pangault , Philippe Ruminy et al.
Blood, 2015, 126 (16), pp.1911 - 1920. ⟨10.1182/blood-2015-04-640912⟩
Journal articles hal-01187301v1
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A Case-report of Unpredictable and Massive Voriconazole Intoxication in a Patient with Extensive CYP2C19 and CYP2C9 Polymorphisms.

Florian Lemaitre , Mathilde Barbaz , Lucie-Marie Scailteux , Fabrice Uhel , Jean-Marc Tadié et al.
Drug Metabolism and Pharmacokinetics, 2013, 28 (5), pp.439-41. ⟨10.2133/dmpk.DMPK-13-NT-007⟩
Journal articles hal-00910224v1
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Decline of multidrug-resistant Gram negative infections with the routine use of a multiple decontamination regimen in ICU

Christophe Camus , Elise Sauvadet , Aude Tavenard , Caroline Piau , Fabrice Uhel et al.
Journal of Infection, 2016, 73 (3), pp.200--209. ⟨10.1016/j.jinf.2016.06.007⟩
Journal articles hal-01395130v1

Liver Cirrhosis is Independently Associated With 90-Day Mortality in ARDS Patients

Arnaud Gacouin , Maxime Locufier , Fabrice Uhel , Julien Letheulle , Pierre Bouju et al.
Shock, 2016, 45 (1), pp.16--21. ⟨10.1097/SHK.0000000000000487⟩
Journal articles hal-01255830v1
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Reply to Patel et al .: Tempering the Clinical Effects of Early Myeloid-derived Suppressor Cell Expansion in Severe Sepsis and Septic Shock

Fabrice Uhel , Christophe Camus , Arnaud Gacouin , Jean-Marc Tadié , Yves Le Tulzo et al.
American Journal of Respiratory and Critical Care Medicine, 2018, 197 (5), pp.678-679. ⟨10.1164/rccm.201709-1854LE⟩
Journal articles hal-01721730v1
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Beneficial effects of citrulline enteral administration on sepsis-induced T cell mitochondrial dysfunction

Florian Reizine , Murielle Grégoire , Mathieu Lesouhaitier , Valentin Coirier , Juliette Gauthier et al.
Proceedings of the National Academy of Sciences of the United States of America, 2022, 119 (8), pp.e2115139119. ⟨10.1073/pnas.2115139119⟩
Journal articles hal-03594344v1
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Cellules suppressives d'origine myéloïde au cours du sepsis

Fabrice Uhel
Médecine humaine et pathologie. Université de Rennes, 2016. Français. ⟨NNT : 2016REN1B002⟩
Theses tel-01480279v1
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Immune Dysfunction After Cardiac Surgery with Cardiopulmonary Bypass: Beneficial Effects of Maintaining Mechanical Ventilation

Baptiste Gaudriot , Fabrice Uhel , Murielle Gregoire , Arnaud Gacouin , Sebastien Biedermann et al.
Shock, 2015, 44 (3), pp.228-233. ⟨10.1097/SHK.0000000000000416⟩
Journal articles hal-01163758v1
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T-cell defect in Diffuse Large B-cell Lymphomas involves expansion of myeloid derived suppressor cells expressing IL-10, PD-L1 and S100A12

Imane Azzaoui , Fabrice Uhel , Delphine Rossille , Celine Pangault , Joelle Dulong et al.
Blood, 2016, 128 (8), pp.1081-1092. ⟨10.1182/blood-2015-08-662783⟩
Journal articles hal-01394657v1
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HMGB1 induces neutrophil dysfunction in experimental sepsis and in patients who survive septic shock

Murielle Grégoire , Jean-Marc Tadié , Fabrice Uhel , Arnaud Gacouin , Caroline Piau et al.
Journal of Leukocyte Biology, 2017, 101 (6), pp.1281-1287. ⟨10.1189/jlb.5HI0316-128RR⟩
Journal articles hal-01533343v1

S116 Cardiopulmonary bypass induces lymphopenia and decreases lymphocyte proliferation ability: IL-10 and PD-L1 as potential therapeutic targets to reduce postoperative infection

Fabrice Uhel , Mathieu Lesouhaitier , Murielle Gregoire , Baptiste Gaudriot , Arnaud Gacouin et al.
Proceedings of Réanimation 2017, the French Intensive Care Society International Congress, 2017, Paris, France. pp.S116, ⟨10.1186/s13613-016-0224-7⟩
Conference papers hal-01446564v1

Enhanced indoleamine 2,3-dioxygenase activity in patients with severe sepsis and septic shock.

Pierre Tattevin , Delphine Monnier , Olivier Tribut , Joelle Dulong , Nadège Bescher et al.
Journal of Infectious Diseases, 2010, 201 (6), pp.956-66. ⟨10.1086/650996⟩
Journal articles hal-00744207v1
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Preclinical septic shock research: why we need an animal ICU

Antoine Guillon , Sébastien Préau , Jérôme Aboab , Eric Azabou , Boris Jung et al.
Annals of Intensive Care, 2019, 9 (1), pp.66. ⟨10.1186/s13613-019-0543-6⟩
Journal articles hal-02153561v1
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Early-stage myeloid-derived suppressor cell count: Basophil exclusion matters

Fabrice Uhel , Imane Azzaoui , Simon Le Gallou , Thierry Fest , Karin Tarte et al.
Journal of Allergy and Clinical Immunology, 2019, 144 (4), pp.1125-1127. ⟨10.1016/j.jaci.2019.06.027⟩
Journal articles hal-02315074v1

Clinical assessment and train-of-four measurements in critically ill patients treated with recommended doses of cisatracurium or atracurium for neuromuscular blockade: a prospective descriptive study

Pierre Bouju , Jean-Marc Tadié , Nicolas Barbarot , Julien Letheulle , Fabrice Uhel et al.
Annals of Intensive Care, 2017, 7 (1), pp.10. ⟨10.1186/s13613-017-0234-0⟩
Journal articles hal-01485180v1

At-risk drinking is independently associated with ICU and one-year mortality in critically ill nontrauma patients*.

Arnaud Gacouin , Jean M Tadie , Fabrice Uhel , Elise Sauvadet , Pierre Fillâtre et al.
Critical Care Medicine, 2014, 42 (4), pp.860-7. ⟨10.1097/CCM.0000000000000041⟩
Journal articles hal-00994580v1
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Multicentric Standardized Flow Cytometry Routine Assessment of Patients With Sepsis to Predict Clinical Worsening

Thomas Daix , Estelle Guerin , Elsa Tavernier , Emmanuelle Mercier , Valérie Gissot et al.
Chest, 2018, 154 (3), pp.617--627. ⟨10.1016/j.chest.2018.03.058⟩
Journal articles hal-01881116v1
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Venoarterial extracorporeal membrane oxygenation induces early immune alterations

Aurelien Frerou , Mathieu Lesouhaitier , Murielle Gregoire , Fabrice Uhel , Arnaud Gacouin et al.
Critical Care, 2021, 25 (1), pp.9. ⟨10.1186/s13054-020-03444-x⟩
Journal articles hal-03134918v1

Short-term decline in all-cause acquired infections with the routine use of a decontamination regimen combining topical polymyxin, tobramycin, and amphotericin B with mupirocin and chlorhexidine in the ICU: a single-center experience.

Christophe Camus , Sylvain Salomon , Claire Bouchigny , Arnaud Gacouin , Sylvain Lavoué et al.
Critical Care Medicine, 2014, 42 (5), pp.1121-30. ⟨10.1097/CCM.0000000000000140⟩
Journal articles hal-01130734v1
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Mycobacterium tuberculosis prosthetic joint infections a case series and literature review

Fabrice Uhel , Gregory Corvaisier , Yves Poinsignon , Catherine Chirouze , Guillaume Béraud et al.
Journal of Infection, 2019, 78 (1), pp.27-34. ⟨10.1016/j.jinf.2018.08.008⟩
Journal articles hal-01862286v1
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Impaired efferocytosis and neutrophil extracellular traps clearance by macrophages in ARDS

Murielle Gregoire , Fabrice Uhel , Mathieu Lesouhaitier , Arnaud Gacouin , Marion Guirriec et al.
European Respiratory Journal, 2018, 52 (2), pp.1702590. ⟨10.1183/13993003.02590-2017⟩
Journal articles hal-01833937v1