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Dioxin-mediated up-regulation of aryl hydrocarbon receptor target genes is dependent on the calcium/calmodulin/CaMKIalpha pathway.

Patricia Monteiro , David Gilot , E. Le Ferrec , Claudine Rauch , Dominique Lagadic-Gossmann et al.
Molecular Pharmacology, 2008, 73 (3), pp.769-77. ⟨10.1124/mol.107.043125⟩
Journal articles hal-00696176v1
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The TALE never ends: a comprehensive overview of the role of PBX1, a TALE transcription factor, in human developmental defects

Laura Mary , Delphine Leclerc , David Gilot , Marc-Antoine Belaud-Rotureau , Sylvie Jaillard et al.
Human Mutation, 2022, 43 (9), pp.1125-1148. ⟨10.1002/humu.24388⟩
Journal articles hal-03660222v1

Cisplatin-induced apoptosis involves a Fas-ROCK-ezrin-dependent actin remodelling in human colon cancer cells.

Amélie Rébillard , Sandrine Jouan-Lanhouet , Elodie Jouan , Patrick Legembre , Mathieu Pizon et al.
European Journal of Cancer, 2010, 46 (8), pp.1445-55. ⟨10.1016/j.ejca.2010.01.034⟩
Journal articles istex hal-00659626v1
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PTPN11 mutations in canine and human disseminated histiocytic sarcoma

Benoit Hedan , Mélanie Rault , Jérôme Abadie , Ronan Ulvé , Nadine Botherel et al.
International Journal of Cancer, 2020, 147 (6), pp.1657-1665. ⟨10.1002/ijc.32991⟩
Journal articles hal-02534873v1

miRNA displacement as a promising approach for cancer therapy

David Gilot , Marie-Dominique Galibert
Molecular & Cellular Oncology, 2018, 5 (1), pp.e1406432. ⟨10.1080/23723556.2017.1406432⟩
Journal articles hal-01730312v1

Identification of a novel CTNNA1 germline mutation predisposing to melanoma: Genotype and functional effects.

Anne Forestier , Laure Masson , Anne-Gaelle Rio , Alexandra Lespagnol , Sarah Guegan et al.
Journal of Clinical Oncology, 2021, 39 (15), pp.e21592. ⟨10.1200/JCO.2021.39.15_suppl.e21592⟩
Journal articles hal-03467176v1
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Key role of caspase-1 in bacterial clearance during S. aureus infection of osteoblasts-like cells.

Elma Lima Leite , Arthur Gautron , Aurélie Nicolas , Jordane Ossemond , Fillipe L R Do Carmo et al.
SFM Microbes 2021, Sep 2021, Nantes, France. , 2021
Conference poster hal-03356389v1
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Inflammasomes involvement in Staphylococcus aureus infection of human osteoblast-like cells MG-63

Elma Lima Leite , Arthur Gautron , Martine Deplanche , Aurélie Nicolas , David Gilot et al.
14.congrès national de la Société Française de Microbiologie (SFM), Oct 2018, Paris, France. , 2018
Conference poster hal-01888292v1
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Canine Oral Melanoma Genomic and Transcriptomic Study Defines Two Molecular Subgroups with Different Therapeutical Targets

Anais Prouteau , Stephanie Mottier , Aline Primot , Edouard Cadieu , Laura Bachelot et al.
Cancers, 2022, 14 (2), pp.276. ⟨10.3390/cancers14020276⟩
Journal articles hal-03555450v1
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A non-coding function of TYRP1 mRNA promotes melanoma growth

David Gilot , Mélodie Migault , Laura Bachelot , Fabrice Journé , Aljosja Rogiers et al.
Nature Cell Biology, 2017, 19 (11), pp.1348-1357. ⟨10.1038/ncb3623⟩
Journal articles hal-01647130v1

Highly efficient SiRNA and gene transfer into hepatocyte-like HepaRG cells and primary human hepatocytes: new means for drug metabolism and toxicity studies.

Véronique Laurent , Denise Glaise , Tobias Nübel , David Gilot , Anne Corlu et al.
Methods in Molecular Biology, 2013, 987, pp.295-314. ⟨10.1007/978-1-62703-321-3_25⟩
Journal articles hal-00865763v1

p53 requires the stress sensor USF1 to direct appropriate cell fate decision

Amine Bouafia , Sébastien Corre , David Gilot , Nicolas Mouchet , Sharon Prince et al.
PLoS Genetics, 2014, 10 (5), pp.e1004309. ⟨10.1371/journal.pgen.1004309⟩
Journal articles hal-01064584v1

Activation of the aryl hydrocarbon receptor by the calcium/calmodulin-dependent protein kinase kinase inhibitor 7-oxo-7H-benzimidazo[2,1-a]benz[de]isoquinoline-3-carboxylic acid (STO-609).

Patricia Monteiro , David Gilot , Sophie Langouet , Olivier Fardel
Drug Metabolism and Disposition, 2008, 36 (12), pp.2556-63. ⟨10.1124/dmd.108.023333⟩
Journal articles hal-00673111v1

Interleukin-8 induction by the environmental contaminant benzo(a)pyrene is aryl hydrocarbon receptor-dependent and leads to lung inflammation.

Normand Podechard , Valérie Lecureur , E. Le Ferrec , Isabelle Guenon , Lydie Sparfel et al.
Toxicology Letters, 2008, 177 (2), pp.130-7. ⟨10.1016/j.toxlet.2008.01.006⟩
Journal articles istex hal-00673238v1

Integrating targeted gene expression and a skin model system to identify functional inhibitors of the UV activated p38 MAP kinase

Amaal Abrahams , Nicolas Mouchet , Nicolas Gouault , Françoise Lohézic-Le Dévéhat , Myriam Le Roch et al.
Photochemical & Photobiological Sciences , 2016, 15 (12), pp.1468-1475. ⟨10.1039/c6pp00283h⟩
Journal articles hal-01439371v1
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The powerful world of antisense oligonucleotides: From bench to bedside

Anais M. Quemener , Laura Bachelot , Anne Forestier , Emmanuelle Donnou-Fournet , David Gilot et al.
Wiley Interdisciplinary Reviews-RNA, 2020, 11 (5), pp.e1594. ⟨10.1002/wrna.1594⟩
Journal articles hal-02565099v1

Human endothelial progenitors constitute targets for environmental atherogenic polycyclic aromatic hydrocarbons.

Julien van Grevenynghe , Patricia Monteiro , David Gilot , Thierry Fest , Olivier Fardel et al.
Biochemical and Biophysical Research Communications, 2006, 341 (3), pp.763-9. ⟨10.1016/j.bbrc.2006.01.028⟩
Journal articles istex hal-00699632v1
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AhR and Arnt differentially regulate NF-κB signaling and chemokine responses in human bronchial epithelial cells.

Johan Øvrevik , Marit Låg , Valerie Lecureur , David Gilot , Dominique Lagadic-Gossmann et al.
Cell Communication and Signaling, 2013, 12, pp.48. ⟨10.1186/s12964-014-0048-8⟩
Journal articles inserm-01085082v1
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TGFβ-induced FOXS1 controls epithelial-mesenchymal transition and predicts a poor prognosis in liver cancer

Kevin Bévant , Matthis Desoteux , Gaëlle Angenard , Raphaël Pineau , Stefano Caruso et al.
International Hepatology Communications, 2022, 6 (5), pp.1157-1171. ⟨10.1002/hep4.1866⟩
Journal articles hal-03456534v1
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Involvement of Kynurenine Pathway in Hepatocellular Carcinoma

Shivani Krishnamurthy , David Gilot , Seong Beom Ahn , Vincent Lam , Joo-Shik Shin et al.
Cancers, 2021, 13 (20), ⟨10.3390/cancers13205180⟩
Journal articles hal-03420190v1
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Discovery of Human-Similar Gene Fusions in Canine Cancers

Ronan Ulvé , Mélanie Rault , Mathieu Bahin , Laetitia Lagoutte , Jérôme Abadie et al.
Cancer Research, 2017, 77 (21), pp.5721-5727. ⟨10.1158/0008-5472.CAN-16-2691⟩
Journal articles hal-01647128v1
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LncRNAs in domesticated animals: from dog to livestock species

Sandrine Lagarrigue , Matthias Lorthiois , Fabien Degalez , David Gilot , Thomas Derrien et al.
Mammalian Genome, 2022, 33 (2), pp.248-270. ⟨10.1007/s00335-021-09928-7⟩
Journal articles hal-03467210v1

Role for mitogen-activated protein kinases in phenobarbital-induced expression of cytochrome P450 2B in primary cultures of rat hepatocytes.

Florence Joannard , Mary Rissel , David Gilot , Alan Anderson , Luz Lefeuvre-Orfila et al.
Toxicology Letters, 2006, 161 (1), pp.61-72. ⟨10.1016/j.toxlet.2005.08.006⟩
Journal articles istex hal-00699951v1
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Inflammasomes involvement in Staphylococcus aureus infection of human osteoblast-like cells MG-63

Elma Lima Leite , Arthur Gautron , Martine Deplanche , Aurélie Nicolas , David Gilot et al.
JAS DSA 2018 Journées d'animation scientifique du département Santé Animale, Oct 2018, Chapelle sur Erdre, France
Conference papers hal-01889269v1
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Overexpression of active Aurora-C kinase results in cell transformation and tumour formation.

Jabbar Khan , Frédéric Ezan , Jean-Yves Crémet , Alain Fautrel , David Gilot et al.
PLoS ONE, 2011, 6 (10), pp.e26512. ⟨10.1371/journal.pone.0026512⟩
Journal articles inserm-00638916v1
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Modulation of Bacterial sRNAs Activity by Epigenetic Modifications Inputs from the Eukaryotic miRNAs

Brice Felden , David Gilot
Genes, 2019, 10 (1), pp.22. ⟨10.3390/genes10010022⟩
Journal articles hal-01993659v1
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Recent Progress in Genome Editing for Gene Therapy Applications: The French Perspective

Mario Amendola , Aurélie Bedel , Ana Buj-Bello , Mathieu Carrara , Jean-Paul Concordet et al.
Human Gene Therapy, 2021, 32 (19-20), pp.1059-1075. ⟨10.1089/hum.2021.191⟩
Journal articles hal-03420183v1

Akti-1/2, an allosteric inhibitor of Akt 1 and 2, efficiently inhibits CaMKIα activity and aryl hydrocarbon receptor pathway.

David Gilot , Fanny Giudicelli , Dominique Lagadic-Gossmann , Olivier Fardel
Chemico-Biological Interactions, 2010, 188 (3), pp.546-52. ⟨10.1016/j.cbi.2010.08.011⟩
Journal articles istex hal-00696150v1
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Blockade of the pro‐fibrotic reaction mediated by the miR‐143/‐145 cluster enhances the responses to targeted therapy in melanoma

Serena Diazzi , Alberto Baeri , Julien Fassy , Margaux Lecacheur , Oskar Marin‐bejar et al.
EMBO Molecular Medicine, 2022, 14 (3), ⟨10.15252/emmm.202115295⟩
Journal articles inserm-03574667v1
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Involvement of caspase-1 in inflammasomes activation and bacterial clearance in S. aureus-infected osteoblast-like MG-63 cells

Elma Lima Leite , Arthur Gautron , Martine Deplanche , Aurélie Nicolas , Jordane Ossemond et al.
Cellular Microbiology, 2020, 22 (8), pp.e13204. ⟨10.1111/cmi.13204⟩
Journal articles hal-02565096v1