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Mutation of Arginine 264 on ERα (Estrogen Receptor Alpha) Selectively Abrogates the Rapid Signaling of Estradiol in the Endothelium Without Altering Fertility

Marine Adlanmerini , Chanaëlle Febrissy , Rana Zahreddine , Emilie Vessières , Melissa Buscato et al.
Arteriosclerosis, Thrombosis, and Vascular Biology, 2020, 40 (9), pp.2143-2158. ⟨10.1161/ATVBAHA.120.314159⟩
Journal articles hal-02929719v1
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The tissue-specific effects of different 17β-estradiol doses reveal the key sensitizing role of AF1 domain in ERα activity

Coralie Fontaine , Melissa Buscato , Alexia Vinel , Frank Giton , Isabelle Raymond-Letron et al.
Molecular and Cellular Endocrinology, 2020, 505, pp.110741. ⟨10.1016/j.mce.2020.110741⟩
Journal articles hal-02470890v1

The transactivating function 1 of estrogen receptor alpha is dispensable for the vasculoprotective actions of 17beta-estradiol.

Audrey Billon-Galés , Coralie Fontaine , Cédric Filipe , Victorine Douin-Echinard , Marie-José Fouque et al.
Proceedings of the National Academy of Sciences of the United States of America, 2009, 106 (6), pp.2053-8. ⟨10.1073/pnas.0808742106⟩
Journal articles hal-00369691v1
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Blood glucose levels and COVID-19. Reply to Sardu C, D’Onofrio N, Balestrieri ML et al [letter] and Lepper PM, Bals R, Jüni P et al [letter]

Bertrand Cariou , Samy Hadjadj , Matthieu Wargny , Matthieu Pichelin , Abdallah Al-Salameh et al.
Diabetologia, 2020, 63 (11), pp.2491-2494. ⟨10.1007/s00125-020-05255-9⟩
Journal articles hal-02935425v1

Tamoxifen elicits atheroprotection through estrogen receptor α AF-1 but does not accelerate reendothelialization.

Coralie Fontaine , Anne Abot , Audrey Billon-Galés , Gilles Flouriot , Hortense Bergès et al.
American Journal of Pathology, 2013, 183 (1), pp.304-12. ⟨10.1016/j.ajpath.2013.03.010⟩
Journal articles hal-00874317v1
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Estetrol prevents western diet-induced obesity and atheroma independently of hepatic estrogen receptor (ER)α

Melissa Buscato , Morgane Davezac , Rana Zahreddine , Marine Adlanmerini , Raphaël Métivier et al.
AJP - Endocrinology and Metabolism, 2021, 320 (1), pp.E19-E29. ⟨10.1152/ajpendo.00211.2020⟩
Journal articles hal-03006849v1

The pro-Th2 cytokine IL-33 directly interacts with invariant NKT and NK cells to induce IFN-gamma production.

Elvire Bourgeois , Linh Pham Van , Michel Samson , Séverine Diem , Anne Barra et al.
European Journal of Immunology, 2009, 39 (4), pp.1046-55. ⟨10.1002/eji.200838575⟩
Journal articles hal-00676402v1

Activation function 2 (AF2) of estrogen receptor-{alpha} is required for the atheroprotective action of estradiol but not to accelerate endothelial healing.

Audrey Billon-Galés , Andrée Krust , Coralie Fontaine , Anne Abot , Gilles Flouriot et al.
Proceedings of the National Academy of Sciences of the United States of America, 2011, 108 (32), pp.13311-6. ⟨10.1073/pnas.1105632108⟩
Journal articles inserm-00615519v1
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Phenotypic characteristics and prognosis of inpatients with COVID-19 and diabetes: the CORONADO study

Bertrand Cariou , Samy Hadjadj , Matthieu Wargny , Matthieu Pichelin , Abdallah Al-Salameh et al.
Diabetologia, 2020, 63 (8), pp.1500-1515. ⟨10.1007/s00125-020-05180-x⟩
Journal articles hal-02667655v2

Gonadal hormonal factors before menopause and incident type 2 diabetes in women: A 22-year follow-up of 83 799 women from the E3N cohort study

Sopio Tatulashvili , Gaelle Gusto , Emmanuel Cosson , Beverley Balkau , Pierre Gourdy et al.
Journal of Diabetes, 2021, ⟨10.1111/1753-0407.13129⟩
Journal articles hal-03105747v1

The uterine and vascular actions of estetrol delineate a distinctive profile of estrogen receptor α modulation, uncoupling nuclear and membrane activation.

Anne Abot , Coralie Fontaine , Mélissa Buscato , Romain Solinhac , Gilles Flouriot et al.
EMBO Molecular Medicine, 2014, 6 (10), pp.1328-46. ⟨10.15252/emmm.201404112⟩
Journal articles hal-01118028v1

The Pro-Th1 cytokine IL-12 enhances IL-4 production by invariant NKT cells: relevance for T cell-mediated hepatitis.

Ren Zhu , Séverine Diem , Luiza M Araujo , Aude Aumeunier , Jordan Denizeau et al.
Journal of Immunology, 2007, 178 (9), pp.5435-42
Journal articles inserm-00314236v1

From in vivo gene targeting of Estrogen Receptors to Optimisation of their Modulation in Menopause.

Jean-François Arnal , Françoise Lenfant , Gilles Flouriot , Florence Tremollières , Henrik Laurell et al.
British Journal of Pharmacology, 2011, 165 (1), pp.57-66. ⟨10.1111/j.1476-5381.2011.01538.x⟩
Journal articles inserm-00615516v1

Membrane and Nuclear Estrogen Receptor Alpha Actions: From Tissue Specificity to Medical Implications

Jean-François Arnal , Françoise Lenfant , Raphaël Métivier , Gilles Flouriot , Daniel Henrion et al.
Physiological Reviews, 2017, 97 (3), pp.1045-1087. ⟨10.1152/physrev.00024.2016⟩
Journal articles hal-01533249v1

The AF-1 activation function of estrogen receptor α is necessary and sufficient for uterine epithelial cell proliferation in vivo.

Anne Abot , Coralie Fontaine , Isabelle Raymond-Letron , Gilles Flouriot , Marine Adlanmerini et al.
Endocrinology, 2013, 154 (6), pp.2222-33. ⟨10.1210/en.2012-2059⟩
Journal articles inserm-00851701v1
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Use of dipeptidyl peptidase-4 inhibitors and prognosis of COVID-19 in hospitalized patients with type 2 diabetes: A propensity score analysis from the CORONADO study

Ronan Roussel , Patrice Darmon , Matthieu Pichelin , Thomas Goronflot , Yawa Abouleka et al.
Diabetes, Obesity and Metabolism, 2021, 23 (5), pp.1162-1172. ⟨10.1111/dom.14324⟩
Journal articles hal-03246543v1