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Localization of Fas/CD95 into the lipid rafts on down-modulation of the phosphatidylinositol 3-kinase signaling pathway.

Marie Bénéteau , Mathieu Pizon , Benjamin Chaigne-Delalande , Sophie Daburon , Patrick Moreau et al.
Molecular Cancer Research, 2008, 6 (4), pp.604-13. ⟨10.1158/1541-7786.MCR-07-0331⟩
Journal articles hal-00674377v1

Cisplatin-induced apoptosis involves a Fas-ROCK-ezrin-dependent actin remodelling in human colon cancer cells.

Amélie Rébillard , Sandrine Jouan-Lanhouet , Elodie Jouan , Patrick Legembre , Mathieu Pizon et al.
European Journal of Cancer, 2010, 46 (8), pp.1445-55. ⟨10.1016/j.ejca.2010.01.034⟩
Journal articles istex hal-00659626v1

An insight into the role of the death receptor CD95 throughout pregnancy Guardian, facilitator, or foe

Lucas Sagrillo-Fagundes , Josianne Bienvenue-Pariseault , Patrick Legembre , Cathy Vaillancourt
Birth Defects Research, 2019, 111 (4), pp.197-211. ⟨10.1002/bdr2.1470⟩
Journal articles hal-02055660v1

New pi3k​/akt​/mtor inhibitors and pharmaceutical uses thereof

Mickael Jean , Amelie Fouque , Patrick Legembre , Pierre van de Weghe
France, Patent n° : WO 2015044229 / EP 2853530. 2015
Patents hal-01139914v1
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Nonapoptotic functions of Fas/CD95 in the immune response

Jean-Philippe Guégan , Patrick Legembre
FEBS Journal, 2018, 285 (5), pp.809-827. ⟨10.1111/febs.14292⟩
Journal articles hal-01744407v1
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The cleaved FAS ligand activates the Na+/H+ exchanger NHE1 through Akt/ROCK1 to stimulate cell motility

Michaël Monet , Mallorie Poet , Sébastien Tauzin , Amelie Fouque , Auréa Cophignon et al.
Scientific Reports, 2016, 6 (1), pp.28008. ⟨10.1038/srep28008⟩
Journal articles hal-01334067v1
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Functional characterization of a chimeric soluble Fas ligand polymer with in vivo anti-tumor activity.

Sophie Daburon , Christel Devaud , Pierre Costet , Aurore Morello , Laure Garrigue-Antar et al.
PLoS ONE, 2013, 8 (1), pp.e54000. ⟨10.1371/journal.pone.0054000⟩
Journal articles hal-00873684v1
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Investigation of Phospholipase Cγ1 Interaction with SLP76 Using Molecular Modeling Methods for Identifying Novel Inhibitors

Neha Tripathi , Iyanar Vetrivel , Stéphane Téletchéa , Mickael Jean , Patrick Legembre et al.
International Journal of Molecular Sciences, 2019, 20 (19), pp.E4721. ⟨10.3390/ijms20194721⟩
Journal articles hal-02307452v1

CD95-Mediated Calcium Signaling Promotes T Helper 17 Trafficking to Inflamed Organs in Lupus-Prone Mice

Amanda Poissonnier , Doriane Sanseau , Matthieu Le Gallo , Marine Malleter , Nicolas Levoin et al.
Immunity, 2016, 45 (1), pp.209--223. ⟨10.1016/j.immuni.2016.06.028⟩
Journal articles hal-01359568v1
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Inhibition of IRE1 RNase activity modulates the tumor cell secretome and enhances response to chemotherapy

Susan E. Logue , Eoghan P. Mcgrath , Patricia Cleary , Stephanie Greene , Katarzyna Mnich et al.
Nature Communications, 2018, 9 (1), pp.3267. ⟨10.1038/s41467-018-05763-8⟩
Journal articles hal-01879955v1

Myeloid-derived suppressor cell, arginase-1, IL-17 and cl-CD95L: an explosive cocktail in lupus?

Robin J. Flynn , Patrick Legembre
Annals of translational medicine, 2016, 4 (24), pp.554. ⟨10.21037/atm.2016.12.35⟩
Journal articles hal-01487934v1

The CD95/CD95L signaling pathway: A role in carcinogenesis

Amélie Fouqué , Patrick Legembre
Cancer Immunology: A Translational Medicine Context, Second Edition, Springer International Publishing, pp.171-188, 2020, 9783030308452. ⟨10.1007/978-3-030-30845-2_11⟩
Book sections hal-02893414v1

S-nitrosylation of the death receptor fas promotes fas ligand-mediated apoptosis in cancer cells.

Lissbeth Leon-Bollotte , Selvakumar Subramaniam , Olivier Cauvard , Stéphanie Plenchette-Colas , Catherine Paul et al.
Gastroenterology, 2011, 140 (7), pp.2009-18, 2018.e1-4. ⟨10.1053/j.gastro.2011.02.053⟩
Journal articles hal-00680824v1

CD95-Mediated Proton Regulation

Sébastien Tauzin , Amelie Fouque , Dominique Lagadic-Gossmann , Pierre Vacher , Patrick Legembre et al.
CD95: Methods and Protocols, Methods in Molecular Biology, vol. 1557,, 6 (1), pp.95-102, 2017, ⟨10.1007/978-1-4939-6780-3_9⟩
Book sections hal-02570274v1

Probing the side chain tolerance for inhibitors of the CD95/PLCγ1 interaction

Ha Thanh Nguyen , Jean-Philippe Guegan , Daniel Best , Pierre van de Weghe , Nicolas Levoin et al.
Bioorganic and Medicinal Chemistry Letters, 2019, 29 (21), pp.126669. ⟨10.1016/j.bmcl.2019.126669⟩
Journal articles hal-02393634v1
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Staphylococcus aureus induces DNA damage in host cell

Martine Deplanche , Nassim Mouhali , Minh-Thu Nguyen , Chantal Cauty , Frederic Ezan et al.
Scientific Reports, 2019, 9 (1), pp.7694. ⟨10.1038/s41598-019-44213-3⟩
Journal articles hal-02153435v1

Correction to A Novel Covalent mTOR Inhibitor, DHM25, Shows in Vivo Antitumor Activity against Triple-Negative Breast Cancer Cells

Amélie Fouqué , Olivier Delalande , Mickael Jean , Rémy Castellano , Emmanuelle Josselin et al.
Journal of Medicinal Chemistry, 2019, 62 (20), pp.9339-9340. ⟨10.1021/acs.jmedchem.9b01578⟩
Journal articles hal-02526957v1

Does calcium contribute to the CD95 signaling pathway?

Pierre Vacher , Nadine Khadra , Anne-Marie Vacher , Emilie Charles , Laurence Bresson-Bepoldin et al.
Anti-Cancer Drugs, 2011, 22 (6), pp.481-7. ⟨10.1097/CAD.0b013e32834433ea⟩
Journal articles hal-00680841v1
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Cleaved CD95L perturbs in vitro macrophages responses to Toxoplasma gondii

Ellen A Tiffney , Janine L Coombes , Patrick Legembre , Robin J Flynn
Microbes and Infection, 2022, 24 (5), pp.104952. ⟨10.1016/j.micinf.2022.104952⟩
Journal articles hal-03632273v1
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Tumor analysis freeze-thawing cycle of triple-negative breast cancer cells alters tumor CD24/CD44 profiles and the percentage of tumor-infiltrating immune cells

Matthieu Le Gallo , Thibault de La Motte Rouge , Amanda Poissonnier , Vincent Lavoue , Patrick Tas et al.
BMC Research Notes, 2018, 11 (1), pp.401. ⟨10.1186/s13104-018-3504-5⟩
Journal articles hal-01834481v1

Chemotherapy with ceramide in TNBC

Patrick Legembre , Olivier Micheau , Bruno Ségui
Oncoscience, 2015, 2 (10), pp.817--818. ⟨10.18632/oncoscience.196⟩
Journal articles hal-01255869v1

A Novel Covalent mTOR Inhibitor, DHM25, Shows in Vivo Antitumor Activity against Triple-Negative Breast Cancer Cells

Amelie Fouque , Olivier Delalande , Mickael Jean , Remy Castellano , Emmanuelle Josselin et al.
Journal of Medicinal Chemistry, 2015, 58 (16), pp.6559-6573. ⟨10.1021/acs.jmedchem.5b00991⟩
Journal articles hal-01187307v1
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Serum CD95L level correlates with tumor immune infiltration and is a positive prognostic marker for advanced high grade serous ovarian cancer

Thibault de La Motte Rouge , Julien Corne , Aurelie Cauchois , Marie Le Boulch , Clotilde Poupon et al.
Molecular Cancer Research, 2019, 17 (12), pp.2537-2548. ⟨10.1158/1541-7786.MCR-19-0449⟩
Journal articles hal-02304765v1

Guidelines for the use and interpretation of assays for monitoring autophagy.

Daniel J Klionsky , Fabio C Abdalla , Hagai Abeliovich , Robert T Abraham , Abraham Acevedo-Arozena et al.
Autophagy, 2012, 8 (4), pp.445-544. ⟨10.4161/auto.8.4.19496⟩
Journal articles hal-00735751v1

HIV Protease Inhibitors Cure Lupus-Prone Mice and Prevent T Helper 17 Cell-Driven Inflammation By Inhibiting CD95-Non-Apoptotic Signaling Pathway

Manon Charrier , Amanda Poissonnier , Daniel Best , Jean-Philippe Guégan , Nicolas Levoin et al.
Arthritis & rheumatology, 2018, 70 (suppl 10)
Journal articles hal-01940201v1
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Staphylococcus aureus alters cell cycle in human and bovine epithelial cells

Ludmila Alekseeva , Lucie Rault , Sintia Almeida da Silva , Fabien Cousin , Patrick Legembre et al.
16. International Symposium on Staphylococci and Staphylococcal Infections, Aug 2014, Chicago, United States. 2014
Conference poster hal-01209709v1

The plasma membrane: a catalyst in the decision to die or not to die?

Patrick Legembre , Faustino Mollinedo
Recent Pat Anticancer Drug Discov, 2011, 6 (3), pp.271-3. ⟨10.2174/157489211796957810⟩
Journal articles hal-00682082v1
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Staphylococcus aureus-induced G2/M phase transition delay in host epithelial cells increases bacterial infective efficiency.

Ludmila Alekseeva , Lucie Rault , Sintia Almeida , Patrick Legembre , Valérie Edmond et al.
PLoS ONE, 2013, 8 (5), pp.e63279. ⟨10.1371/journal.pone.0063279⟩
Journal articles hal-00873672v1