Search - Université de Rennes Access content directly

Filter your results

15 Results
authFullName_s : Simon Bucher

Modulation of metabolizing enzymes by bisphenol a in human and animal models.

Nicolas Quesnot , Simon Bucher , Bernard Fromenty , Marie-Anne Robin
Chemical Research in Toxicology, 2014, 27 (9), pp.1463-73. ⟨10.1021/tx500087p⟩
Journal articles hal-01134758v1
Image document

Mechanisms involved in the death of steatotic WIF-B9 hepatocytes co-exposed to benzo[a]pyrene and ethanol a possible key role for xenobiotic metabolism and nitric oxide

Arnaud Tête , Isabelle Gallais , Muhammad Imran , Martine Chevanne , Marie Liamin et al.
Free Radical Biology and Medicine, 2018, 129, pp.323-337. ⟨10.1016/j.freeradbiomed.2018.09.042⟩
Journal articles hal-01888877v1
Image document

A cellular model to study drug-induced liver injury in nonalcoholic fatty liver disease: application to acetaminophen

Anaïs Michaut , Dounia Le Guillou , Caroline Moreau , Simon Bucher , Mitchell R. Mcgill et al.
Toxicology and Applied Pharmacology, 2016, 292, pp.40-55. ⟨10.1016/j.taap.2015.12.020⟩
Journal articles hal-01255826v1
Image document

Transcriptomic analysis in zebrafish larvae identifies iron-dependent mitochondrial dysfunction as a possible key event of NAFLD progression induced by benzo[a]pyrene/ethanol co-exposure

Muhammad Imran , Frédéric Chalmel , Odile Sergent , Bertrand Evrard , Hélène Le Mentec et al.
Cell Biology and Toxicology, 2022, ⟨10.1007/s10565-022-09706-4⟩
Journal articles hal-03647402v1
Image document

Moderate chronic ethanol consumption exerts beneficial effects on nonalcoholic fatty liver in mice fed a high-fat diet possible role of higher formation of triglycerides enriched in monounsaturated fatty acids

Simon Bucher , Karima Begriche , Daniel D. Catheline , Viviane Trak-Smayra , François Tiaho et al.
European Journal of Nutrition, 2020, 59 (4), pp.1619-1632. ⟨10.1007/s00394-019-02017-1⟩
Journal articles hal-02152865v1
Image document

Production of chlorzoxazone glucuronides via cytochrome P4502E1 dependent and independent pathways in human hepatocytes

Nicolas Quesnot , Simon Bucher , Christina Gade , Manuel Vlach , Elise Vene et al.
Archives of Toxicology, 2018, 92 (10), pp.3077-3091. ⟨10.1007/s00204-018-2300-2⟩
Journal articles hal-01863847v1
Image document

Co-exposure to benzo[a]pyrene and ethanol induces a pathological progression of liver steatosis in vitro and in vivo

Simon Bucher , Arnaud Tête , Normand Podechard , Marie Liamin , Dounia Le Guillou et al.
Scientific Reports, 2018, 8 (1), pp.5963. ⟨10.1038/s41598-018-24403-1⟩
Journal articles hal-01771620v1
Image document

Protein kinase C-dependent regulation of human hepatic drug transporter expression

Abdullah Mayati , Marc Le Vee , Amélie Moreau , Elodie Jouan , Simon Bucher et al.
Biochemical Pharmacology, 2015, 98 (4), pp.703-717. ⟨10.1016/j.bcp.2015.10.007⟩
Journal articles hal-01216205v1
Image document

Bisphenol A induces steatosis in HepaRG cells using a model of perinatal exposure

Simon Bucher , Pégah Jalili , Dounia Le Guillou , Karima Begriche , Karine Rondel et al.
Environmental Toxicology, 2017, 32 (3), pp.1024-1036. ⟨10.1002/tox.22301⟩
Journal articles hal-01470709v1

Regulation of hepatic drug transporter activity and expression by organochlorine pesticides

Simon Bucher , Marc Le Vee , Elodie Jouan , Olivier Fardel
Journal of Biochemical and Molecular Toxicology, 2014, 28 (3), pp.119--128. ⟨10.1002/jbt.21543⟩
Journal articles istex hal-01063656v1

Polycyclic aromatic hydrocarbons can trigger hepatocyte release of extracellular vesicles by various mechanisms of action depending on their affinity for the aryl hydrocarbon receptor

Nettie van Meteren , Dominique Lagadic-Gossmann , Martine Chevanne , Isabelle Gallais , Dimitri Gobart et al.
Toxicological Sciences, 2019, 171 (2), pp.443-462. ⟨10.1093/toxsci/kfz157⟩
Journal articles hal-02280777v1
Image document

Drug-induced hepatic steatosis in absence of severe mitochondrial dysfunction in HepaRG cells: proof of multiple mechanism-based toxicity

Julien Allard , Simon Bucher , Julie Massart , Pierre-Jean Ferron , Dounia Le Guillou et al.
Cell Biology and Toxicology, 2021, 37 (2), pp.151-175. ⟨10.1007/s10565-020-09537-1⟩
Journal articles hal-02886702v1
Image document

Non-oxidative ethanol metabolism in human hepatic cells in vitro Involvement of uridine diphospho-glucuronosyltransferase 1A9 in ethylglucuronide production

Chloé Hugbart , Yann Verres , Brendan Le Daré , Simon Bucher , Elise Vène et al.
Toxicology in Vitro, 2020, 66, pp.104842. ⟨10.1016/j.tiv.2020.104842⟩
Journal articles hal-02563466v1
Image document

Possible Involvement of Mitochondrial Dysfunction and Oxidative Stress in a Cellular Model of NAFLD Progression Induced by Benzo[a]pyrene/Ethanol CoExposure

Simon Bucher , Dounia Le Guillou , Julien Allard , Gregory Pinon , Karima Begriche et al.
Oxidative Medicine and Cellular Longevity, 2018, 2018, pp.4396403. ⟨10.1155/2018/4396403⟩
Journal articles hal-01861586v1
Image document

Drug-Induced Alterations of Mitochondrial DNA Homeostasis in Steatotic and Nonsteatotic HepaRG Cells

Dounia Le Guillou , Simon Bucher , Karima Begriche , Delphine Hoët , Anne Lombès et al.
Journal of Pharmacology and Experimental Therapeutics, 2018, 365 (3), pp.711-726. ⟨10.1124/jpet.117.246751⟩
Journal articles hal-01808097v1