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authFullName_s : Rémy Le Guevel
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Rho-kinase/myosin light chain kinase pathway plays a key role in the impairment of bile canaliculi dynamics induced by cholestatic drugs

Ahmad Sharanek , Audrey Burban , Matthew Burbank , Rémy Le Guevel , Ruoya Li et al.
Scientific Reports, 2016, 6 (1), pp.24709. ⟨10.1038/srep24709⟩
Journal articles hal-01326368v1

Microwave Assisted Organic Synthesis (MAOS) of New Dispacamide A Derivatives Bearing a Thiazolinone Platform, Biological Assays on Inhibition of Protein Kinases and Cell Effects

Solene Guiheneuf , Ludovic Paquin , Francois Carreaux , Emilie Durieu , Helene Benedetti et al.
Current microwave chemistry, 2014, 1 (1), pp.33-40. ⟨10.2174/22133356114019990002⟩
Journal articles hal-01114583v1
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Synthesis and biological studies of new piperidino-1,2,3-triazole hybrids with 3-aryl isoxazole side chains

Appala Venkata Ramana Murthy , Vennu Narendar , Nangunoori Sampath Kumar , Pasula Aparna , Anagani Kanaka Durga Bhavani et al.
Bioorganic & Medicinal Chemistry Letters, 2021, 52, pp.128390. ⟨10.1016/j.bmcl.2021.128390⟩
Journal articles hal-03414697v1

Synthesis and biological evaluation of 2,3-bis(het)aryl-4-azaindole derivatives as protein kinase inhibitors

Frédéric Pin , Frédéric Buron , Fabienne Saab , Lionel Colliandre , Stéphane Bourg et al.
MedChemComm, 2011, 2 (9), pp.899-903. ⟨10.1039/c1md00141h⟩
Journal articles hal-00720699v1
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Synthesis of new pyridazino[4,5-b]indol-4-ones and pyridazin-3(2H)-one analogs as DYRK1A inhibitors

Amélie Bruel , Romain Bénéteau , Mylène Chabanne , Olivier Lozach , Rémy Le Guevel et al.
Bioorganic and Medicinal Chemistry Letters, 2014, 24 (21), pp.5037 - 5040. ⟨10.1016/j.bmcl.2014.09.017⟩
Journal articles hal-01086026v1

Automated detection of hepatotoxic compounds in human hepatocytes using HepaRG cells and image-based analysis of mitochondrial dysfunction with JC-1 dye.

K. Pernelle , Rémy Le Guevel , Denise Glaise , C Gaucher-Di Stasio , T. Le Charpentier et al.
Toxicology and Applied Pharmacology, 2011, 254 (3), pp.256-66. ⟨10.1016/j.taap.2011.04.018⟩
Journal articles istex hal-00740177v1

Novel optimization of valmerins (tetrahydropyrido[1,2-a]isoindolones) as potent dual CDK5/GSK3 inhibitors

Aziz Ouach , Rajâa Boulahjar , Christine Vala , Stéphane Bourg , Pascal Bonnet et al.
European Journal of Medicinal Chemistry, 2016, 115, pp.311--325. ⟨10.1016/j.ejmech.2016.02.072⟩
Journal articles hal-01295635v1
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At the crossroads of fertility and metabolism

Pascal Froment , Ingrid Plotton , Cecilia Giulivi , Stéphane Fabre , Rita Khoueiry et al.
Human Reproduction, 2022, 37 (6), pp.1207-1228. ⟨10.1093/humrep/deac067⟩
Journal articles hal-03658093v1
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Discovery of DB18, a potent inhibitor of CLK kinases with a high selectivity against DYRK1A kinase

Dabbugoddu Brahmaiah , Anagani Kanaka Durga Bhavani , Pasula Aparna , Nangunoori Sampath Kumar , Hélène Solhi et al.
Bioorganic and Medicinal Chemistry, 2021, 31, pp.115962. ⟨10.1016/j.bmc.2020.115962⟩
Journal articles hal-03128547v1