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Rho-kinase/myosin light chain kinase pathway plays a key role in the impairment of bile canaliculi dynamics induced by cholestatic drugs
Ahmad Sharanek
,
Audrey Burban
,
Matthew Burbank
,
Rémy Le Guevel
,
Ruoya Li
et al.
Journal articles
hal-01326368v1
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Microwave Assisted Organic Synthesis (MAOS) of New Dispacamide A Derivatives Bearing a Thiazolinone Platform, Biological Assays on Inhibition of Protein Kinases and Cell Effects
Solene Guiheneuf
,
Ludovic Paquin
,
Francois Carreaux
,
Emilie Durieu
,
Helene Benedetti
et al.
Journal articles
hal-01114583v1
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Synthesis and biological studies of new piperidino-1,2,3-triazole hybrids with 3-aryl isoxazole side chains
Appala Venkata Ramana Murthy
,
Vennu Narendar
,
Nangunoori Sampath Kumar
,
Pasula Aparna
,
Anagani Kanaka Durga Bhavani
et al.
Journal articles
hal-03414697v1
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Synthesis and biological evaluation of 2,3-bis(het)aryl-4-azaindole derivatives as protein kinase inhibitors
Frédéric Pin
,
Frédéric Buron
,
Fabienne Saab
,
Lionel Colliandre
,
Stéphane Bourg
et al.
Journal articles
hal-00720699v1
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Synthesis of new pyridazino[4,5-b]indol-4-ones and pyridazin-3(2H)-one analogs as DYRK1A inhibitors
Amélie Bruel
,
Romain Bénéteau
,
Mylène Chabanne
,
Olivier Lozach
,
Rémy Le Guevel
et al.
Journal articles
hal-01086026v1
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Automated detection of hepatotoxic compounds in human hepatocytes using HepaRG cells and image-based analysis of mitochondrial dysfunction with JC-1 dye.
K. Pernelle
,
Rémy Le Guevel
,
Denise Glaise
,
C Gaucher-Di Stasio
,
T. Le Charpentier
et al.
Journal articles
istex
hal-00740177v1
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Novel optimization of valmerins (tetrahydropyrido[1,2-a]isoindolones) as potent dual CDK5/GSK3 inhibitors
Aziz Ouach
,
Rajâa Boulahjar
,
Christine Vala
,
Stéphane Bourg
,
Pascal Bonnet
et al.
Journal articles
hal-01295635v1
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At the crossroads of fertility and metabolism
Pascal Froment
,
Ingrid Plotton
,
Cecilia Giulivi
,
Stéphane Fabre
,
Rita Khoueiry
et al.
Journal articles
hal-03658093v1
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Discovery of DB18, a potent inhibitor of CLK kinases with a high selectivity against DYRK1A kinase
Dabbugoddu Brahmaiah
,
Anagani Kanaka Durga Bhavani
,
Pasula Aparna
,
Nangunoori Sampath Kumar
,
Hélène Solhi
et al.
Journal articles
hal-03128547v1
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