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Highly efficient SiRNA and gene transfer into hepatocyte-like HepaRG cells and primary human hepatocytes: new means for drug metabolism and toxicity studies.
Véronique Laurent
,
Denise Glaise
,
Tobias Nübel
,
David Gilot
,
Anne Corlu
et al.
Journal articles
hal-00865763v1
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Preferential induction of the AhR gene battery in HepaRG cells after a single or repeated exposure to heterocyclic aromatic amines.
Julie Dumont
,
Rozenn Jossé
,
Carine Lambert
,
Sébastien Anthérieu
,
Véronique Laurent
et al.
Journal articles
istex
hal-00742145v1
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Reduced cardiolipin content decreases respiratory chain capacities and increases ATP synthesis yield in the human HepaRG cells
Laure Peyta
,
Kathleen Jarnouen
,
Michelle Pinault
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Cyrille Guimaraes
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Jean-Paul Pais de Barros
et al.
Journal articles
hal-01259219v1
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Highly efficient gene transfer into hepatocyte-like HepaRG cells: new means for drug metabolism and toxicity studies
Véronique Laurent
,
Aurore Fraix
,
Tristan Montier
,
Sandrine Cammas-Marion
,
Catherine Ribault
et al.
Journal articles
hal-00552337v1
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Natural and synthetic poly(malic acid)-based derivates: A family of versatile biopolymers for the design of drug nanocarriers.
Pascal Loyer
,
Sandrine Cammas-Marion
Journal articles
hal-01063205v1
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Ethanol upregulates the P2X7 purinergic receptor in human macrophages
Brendan Le Dare
,
Tatiana Victoni
,
Aude Bodin
,
Manuel Vlach
,
Elise Vene
et al.
Journal articles
hal-01937258v1
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Cytochrome P450 1A1/2, 2B6 and 3A4 HepaRG cell-based biosensors to monitor hepatocyte differentiation, drug metabolism and toxicity
Manuel Vlach
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Nicolas Quesnot
,
Hélène Dubois-Pot-Schneider
,
Catherine Ribault
,
Yann Verres
et al.
Journal articles
hal-02152870v1
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Regulation of the hepatocyte cell cycle: signaling pathways and protein kinases.
Pascal Loyer
,
Anne Corlu
,
Chantal Desdouets
Journal articles
inserm-00864155v1
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Reperfusion stress induced during intermittent selective clamping accelerates rat liver regeneration through JNK pathway.
Hélène Duval
,
Sasse-Fanie Mbatchi
,
Stéphane Grandadam
,
Claire Legendre
,
Pascal Loyer
et al.
Journal articles
istex
hal-00742147v1
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Identification of Novel Compounds Inhibiting the Kinase Activity of the CDK5/p25 Complex via Direct Binding to p25
Riheb Jabeur
,
Caroline Corbel
,
Pascal Loyer
,
Annabelle Le Parc
,
Adelaide Le Grand
et al.
Journal articles
hal-04089029v1
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Production of chlorzoxazone glucuronides via cytochrome P4502E1 dependent and independent pathways in human hepatocytes
Nicolas Quesnot
,
Simon Bucher
,
Christina Gade
,
Manuel Vlach
,
Elise Vene
et al.
Journal articles
hal-01863847v1
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IL-1β production is dependent of the activation of purinergic receptors and NLRP3 pathway in human macrophages
Thomas Gicquel
,
Sacha Robert
,
Pascal Loyer
,
Tatiana Victoni
,
Aude Bodin
et al.
Journal articles
hal-01169797v1
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Circumsporozoite Protein of Plasmodium berghei- and George Baker Virus A-Derived Peptides Trigger Efficient Cell Internalization of Bioconjugates and Functionalized Poly(ethylene glycol)-b-poly(benzyl malate)-Based Nanoparticles in Human Hepatoma Cells
Elise Vene
,
Kathleen Jarnouen
,
Catherine Ribault
,
Manuel Vlach
,
Yann Verres
et al.
Journal articles
hal-03657832v1
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Degradable and biocompatible nanoparticles decorated with cyclic RGD peptide for efficient drug delivery to hepatoma cells in vitro.
Pascal Loyer
,
Wahib Bedhouche
,
Zhi Wei Huang
,
Sandrine Cammas-Marion
Journal articles
hal-00861299v1
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Synthetic vectors for gene delivery: An overview of their evolution depending on routes of administration
Nawal Belmadi
,
Patrick Midoux
,
Pascal Loyer
,
Catherine Passirani
,
Chantal Pichon
et al.
Journal articles
istex
hal-01162373v1
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Alteration of immunophenotype of human macrophages and monocytes after exposure to cigarette smoke
Camila Oliveira da Silva
,
Thomas Gicquel
,
Yoann Daniel
,
Thiago Bartholo
,
Elise Vene
et al.
Journal articles
hal-02929043v1
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Overview of Radiolabeled Somatostatin Analogs for Cancer Imaging and Therapy
Romain Eychenne
,
Christelle Bouvry
,
Mickael Bourgeois
,
Pascal Loyer
,
Eric Benoist
et al.
Journal articles
hal-02957763v1
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Culture Conditions Promoting Hepatocyte Proliferation and Cell Cycle Synchronization
Anne Corlu
,
Pascal Loyer
Journal articles
hal-01187298v1
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Araf51 with improved transglycosylation activities: One engineered biocatalyst for one specific acceptor
Alizé Pennec
,
Richard Daniellou
,
Pascal Loyer
,
Caroline Nugier-Chauvin
,
Vincent Ferrières
et al.
Journal articles
hal-01086640v1
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New functional degradable and bio-compatible nanoparticles based on poly(malic acid) derivatives for site-specific anti-cancer drug delivery.
Zhi Wei Huang
,
Véronique Laurent
,
Ghizlane Chetouani
,
Julia Y. Ljubimova
,
Eggehard Holler
et al.
Journal articles
inserm-00864846v1
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Evaluation of genotoxicity using automated detection of γH2AX in metabolically competent HepaRG cells
Nicolas Quesnot
,
Karine Rondel
,
Marc Audebert
,
Sophie Martinais
,
Denise Glaise
et al.
Journal articles
hal-01187325v1
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Roles of CDK/Cyclin complexes in transcription and pre-mRNA splicing Cyclins L and CDK11 at the cross-roads of cell cycle and regulation of gene expression
Pascal Loyer
,
Janeen H Trembley
Journal articles
hal-02864472v1
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Regulation of hepatic cardiolipin metabolism by TNFα: Implication in cancer cachexia
Laure Peyta
,
Kathleen Jarnouen
,
Michelle Pinault
,
Cédric Coulouarn
,
Cyrille Guimaraes
et al.
Journal articles
hal-01197346v1
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Combined Stimulation with the Tumor Necrosis Factor α and the Epidermal Growth Factor Promotes the Proliferation of Hepatocytes in Rat Liver Cultured Slices.
Francis Finot
,
Régis Masson
,
Fabienne Desmots
,
Catherine Ribault
,
Nicole Bichet
et al.
Journal articles
inserm-00864148v1
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Synthesis of Poly(Dimethylmalic Acid) Homo- and Copolymers to Produce Biodegradable Nanoparticles for Drug Delivery Cell Uptake and Biocompatibility Evaluation in Human Heparg Hepatoma Cells
Ali Khalil
,
Saad Saba
,
Catherine Le Ribault
,
Manuel Vlach
,
Pascal Loyer
et al.
Journal articles
hal-02930234v1
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Dosimetric parameters predicting contralateral liver hypertrophy after unilobar radioembolization of hepatocellular carcinoma
Xavier Palard
,
Julien Edeline
,
Yan Rolland
,
Samuel Le Sourd
,
Marc Pracht
et al.
Journal articles
hal-01709935v1
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Liposome-Mediated Gene Transfer in Differentiated HepaRG™ Cells: Expression of Liver Specific Functions and Application to the Cytochrome P450 2D6 Expression
Manuel Vlach
,
Hugo Coppens-Exandier
,
Agnès Jamin
,
Mathieu Berchel
,
Julien Scaviner
et al.
Journal articles
hal-03930086v1
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Poly(malic acid) bearing Doxorubicin and N-Acetyl Galactosamine as a site-specific prodrug for targeting hepatocellular carcinoma
Nivishna Venkatraj
,
M. J. Nanjan
,
Pascal Loyer
,
M. J. N. Chandrasekar
,
Sandrine Cammas-Marion
et al.
Journal articles
hal-01579649v1
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Elaboration of nanocarriers based on biocompatible polymers for the specific vectorisation of an imaging agent
Oceane Malval
,
Elise Vene
,
Pascal Loyer
,
Sandrine Cammas-Marion
,
Nicolas Lepareur
et al.
Journal of Labelled Compounds and Radiopharmaceuticals, 2019, 62, pp.S356-S357
Journal articles
hal-02177795v1
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Low-Dose Pesticides Alter Primary Human Bone Marrow Mesenchymal Stem/Stromal Cells through ALDH2 Inhibition
Amélie Foucault
,
Noemie Ravalet
,
Joevin Besombes
,
Frédéric Picou
,
Nathalie Gallay
et al.
Journal articles
hal-03468294v1
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