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authFullName_s : Odile Sergent

Implication des radeaux lipidiques dans l'apoptose induite par le benzo(a)pyrène

Xavier Tekpli , Mary Rissel , Laurence Huc , Daniel D. Catheline , Morgane Gorria et al.
Journée OUEST-genopole. Lipides, lipidomique et stress oxydant, Apr 2008, Nantes, France
Conference papers hal-00675819v1
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Protective effect of monosialoganglioside GM1 against chemically induced apoptosis through targeting of mitochondrial function and iron transport.

Morgane Gorria , Laurence Huc , Odile Sergent , Amélie Rébillard , François Gaboriau et al.
Biochemical Pharmacology, 2006, 72 (10), pp.1343-53. ⟨10.1016/j.bcp.2006.07.014⟩
Journal articles hal-00699820v1
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Environmental carcinogenesis and pH homeostasis: Not only a matter of dysregulated metabolism

Kévin Hardonniere , Laurence Huc , Odile Sergent , Jørn A Holme , Dominique Lagadic-Gossmann et al.
Seminars in Cancer Biology, 2017, 43, pp.49-65. ⟨10.1016/j.semcancer.2017.01.001⟩
Journal articles hal-01531077v1

Opposite effects of docosahexaenoic acid and eicosapentaenoic acid on ethanol-induced toxicity in primary rat hepatocytes

Fatiha Djoudi , Marie-Thérèse Dimanche-Boitrel , Martine Chevanne , Mary Rissel , Laure Debure et al.
6th GERLI Lipidomics Meeting. Bioactive Lipids, Nutrition and Health, Jul 2009, Rennes, France
Conference papers hal-00675812v1

Downregulation of ceramide synthase-6 during epithelial-to-mesenchymal transition reduces plasma membrane fluidity and cancer cell motility

Valérie Edmond , Florent Dufour , Guillaume Poiroux , Kenji Shoji , Marine Malleter et al.
Oncogene, 2015, 34 (8), pp.996-1005. ⟨10.1038/onc.2014.55⟩
Journal articles hal-01063558v1

Polycyclic aromatic hydrocarbons can trigger a hepatocyte release of cytotoxic extracellular vesicles

Nettie van Meteren , Martine Chevanne , Isabelle Gallais , Fabienne Gauffre , Soizic Chevance et al.
Journal of Hepatology, 2019, 70 (1), pp.E811. ⟨10.1016/S0618-8278(19)31622-6⟩
Journal articles hal-02149788v1

Ahr-dependent lipid membrane remodelling: an early step facilitating benzo[a]pyrene-induced apoptosis

Jørn A. Holme , Xavier Tekpli , Béatrice Dendelé , Laure Debure , Odile Sergent et al.
49th annual meeting of Society of Toxicology and ToxExpo, Mar 2010, Salt Lake City, United States
Conference papers hal-00675239v1
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Zebrafish larva as a reliable model for in vivo assessment of membrane remodeling involvement in the hepatotoxicity of chemical agents

Normand Podechard , Martine Chevanne , Morgane Fernier , Arnaud Tête , Aurore Collin et al.
Journal of Applied Toxicology, 2017, 37 (6), pp.732-746. ⟨10.1002/jat.3421⟩
Journal articles hal-01526425v1
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Co-exposure to benzo[a]pyrene and ethanol induces a pathological progression of liver steatosis in vitro and in vivo

Simon Bucher , Arnaud Tête , Normand Podechard , Marie Liamin , Dounia Le Guillou et al.
Scientific Reports, 2018, 8 (1), pp.5963. ⟨10.1038/s41598-018-24403-1⟩
Journal articles hal-01771620v1
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Protective Action of Ostreococcus tauri and Phaeodactylum tricornutum Extracts towards Benzo[a]Pyrene-Induced Cytotoxicity in Endothelial Cells

Manon Le Goff , Antoine Delbrut , Marie Quinton , Rémi Pradelles , Maelle Bescher et al.
Marine drugs, 2019, 18 (1), ⟨10.3390/md18010003⟩
Journal articles hal-02441226v1

Induction d'un stress oxydant suite à la modification de la signalisation cellulaire dépendant des radeaux lipidiques par l'intoxication alcoolique

Odile Sergent
Journée "Stress Oxydant" - IFR 140 GFAS Axe "Perturbations Métaboliques et Stress", Jun 2006, Rennes, France
Conference papers hal-00699959v1

Effet de l'éthanol sur le pool labile de fer intracellulaire : impact des variations de fluidité membranaire

Odile Sergent
3e journée de l'IFR 140 GFAS Axe "Métabolisme du fer et ses pathologies", Jan 2006, Rennes, France
Conference papers hal-00699956v1

An acidic extracellular pH tumoral environment switches TRAIL-induced apoptosis to necrosis via PARP-1 activation in human colon and liver cancer cells

Sandrine Jouan-Lanhouet , Gwenaelle Le Moigne-Müller , Corinne Martin-Chouly , Odile Sergent , Dominique Lagadic-Gossmann et al.
13ème Colloque Cytokines du Croisic (Société Française d'Immunologie), May 2010, Presqu'île du Croisic, France
Conference papers hal-00675259v1

Cisplatin-induced apoptosis involves a Fas-ROCK-ezrin-dependent actin remodelling in human colon cancer cells.

Amélie Rébillard , Sandrine Jouan-Lanhouet , Elodie Jouan , Patrick Legembre , Mathieu Pizon et al.
European Journal of Cancer, 2010, 46 (8), pp.1445-55. ⟨10.1016/j.ejca.2010.01.034⟩
Journal articles istex hal-00659626v1
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Identification of the couple GSK3α/c-Myc as a new regulator of hexokinase II in benzo[a]pyrene-induced apoptosis.

Béatrice Dendelé , Xavier Tekpli , Odile Sergent , Marie-Thérèse Dimanche-Boitrel , Jørn A. Holme et al.
Toxicology in Vitro, 2012, 26 (1), pp.94-101. ⟨10.1016/j.tiv.2011.11.001⟩
Journal articles hal-00682104v1
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Benzo[a]pyrene-induced nitric oxide production acts as a survival signal targeting mitochondrial membrane potential

Kevin Hardonnière , Laurence Huc , Normand Podechard , Morgane Fernier , Xavier Tekpli et al.
Toxicology in Vitro, 2015, 29 (7), pp.1597-1608. ⟨10.1016/j.tiv.2015.06.010⟩
Journal articles hal-01163757v1
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Disturbances in H dynamics during environmental carcinogenesis

Dominique Lagadic-Gossmann , Kévin Hardonnière , Baharia Mograbi , Odile Sergent , Laurence Huc et al.
Biochimie, 2019, 163 (163), pp.171-183. ⟨10.1016/j.biochi.2019.06.013⟩
Journal articles hal-02179386v1
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Transcriptomic analysis in zebrafish larvae identifies iron-dependent mitochondrial dysfunction as a possible key event of NAFLD progression induced by benzo[a]pyrene/ethanol co-exposure

Muhammad Imran , Frédéric Chalmel , Odile Sergent , Bertrand Evrard , Hélène Le Mentec et al.
Cell Biology and Toxicology, 2022, ⟨10.1007/s10565-022-09706-4⟩
Journal articles hal-03647402v1
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Extracellular vesicles released by polycyclic aromatic hydrocarbons-treated hepatocytes trigger oxidative stress in recipient hepatocytes by delivering iron

Nettie van Meteren , Dominique Lagadic-Gossmann , Normand Podechard , Dimitri Gobart , Isabelle Gallais et al.
Free Radical Biology and Medicine, 2020, 160, pp.246-262. ⟨10.1016/j.freeradbiomed.2020.08.001⟩
Journal articles hal-02930146v1
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The environmental carcinogen benzo[a]pyrene induces a Warburg-like metabolic reprogramming dependent on NHE1 and associated with cell survival

Kevin Hardonnière , Elise Saunier , Anthony Lemarié , Morgane Fernier , Isabelle Gallais et al.
Scientific Reports, 2016, 6 (1), pp.30776. ⟨10.1038/srep30776⟩
Journal articles hal-01359569v1

Carcinogen-induced lipid membrane remodelling is essential for the NHE-1 activation involved in related apoptosis

Xavier Tekpli , Béatrice Dendelé , Laure Debure , Odile Sergent , Maryvonne Rissel et al.
2nd International Meeting 2010 "Ion channels and Cancer", Mar 2010, Florence, Italy
Conference papers hal-00675245v1
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Could Fucoxanthin Interaction with Lipid Rafts Mediate its Cytotoxicity in Cancer Cells?

Raimundo Gonçalves Oliveira-Junior , Valérie Thiéry , Odile Sergent , Martine Chevanne , Laurent Picot et al.
Journal of Oceanography and Marine Research, 2016, 4 (1), pp.1000144. ⟨10.4172/jomr.1000144⟩
Journal articles hal-01391001v1

L'apoptose induite par le cisplatine implique une augmentation de la fluidité membranaire via l'inhibition de l'échangeur sodium-proton NHE1 dans les cellules cancéreuses coliques humaines

Amélie Rébillard , Xavier Tekpli , Olivier Meurette , Odile Sergent , Gwenaelle Le Moigne-Müller et al.
Congrès de la SPTC (Société de Pharmaco-Toxicologie Cellulaire), Le stress environnemental : approches cellulaires et moléculaires, Sep 2007, Rennes, France
Conference papers hal-00690396v1

TRAIL induces necroptosis involving RIPK1/RIPK3-dependent PARP-1 activation.

Sandrine Jouan-Lanhouet , M. I. Arshad , Claire Piquet-Pellorce , Corinne Martin-Chouly , Gwenaelle Le Moigne-Muller et al.
Cell Death and Differentiation, 2012, 19 (12), pp.2003-14. ⟨10.1038/cdd.2012.90⟩
Journal articles inserm-00871432v1

Cisplatin-induced apoptosis involves membrane fluidification via inhibition of NHE1 in human colon cancer cells.

Amélie Rébillard , Xavier Tekpli , Olivier Meurette , Odile Sergent , Gwenaëlle Lemoigne-Muller et al.
Cancer Research, 2007, 67 (16), pp.7865-74. ⟨10.1158/0008-5472.CAN-07-0353⟩
Journal articles hal-00690301v1
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On the role of the difference in surface tensions involved in the allosteric regulation of NHE-1 induced by low to mild osmotic pressure, membrane tension and lipid asymmetry.

Vincent Pang , Laurent Counillon , Dominique Lagadic-Gossmann , Mallorie Poet , Jérôme Lacroix et al.
Cell Biochemistry and Biophysics, 2012, 63 (1), pp.47-57. ⟨10.1007/s12013-012-9340-7⟩
Journal articles inserm-00871709v1

Exemple de Fédération sur le Stress Oxydant: "Le Pôle Rennais

Odile Sergent
Journée OUEST-genopole® "Stress Oxydant" en partenariat avec l'IFR 140 "Thème Stress Oxydant", Jun 2007, Rennes, France
Conference papers hal-00690354v1

Rôle des radeaux lipidiques dans le stress oxydant induit par l'éthanol

Odile Sergent
"Stress oxydant et réponses cellulaires" Forum SFTG (société française de toxicologie génétique), Institut Gustave Roussy, May 2010, Villejuif, France
Conference papers hal-00674762v1

Membrane remodeling, an early event in benzo[a]pyrene-induced apoptosis.

Xavier Tekpli , Mary Rissel , Laurence Huc , Daniel D. Catheline , Odile Sergent et al.
Toxicology and Applied Pharmacology, 2010, 243 (1), pp.68-76. ⟨10.1016/j.taap.2009.11.014⟩
Journal articles istex hal-00660136v1
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Mechanisms involved in the death of steatotic WIF-B9 hepatocytes co-exposed to benzo[a]pyrene and ethanol a possible key role for xenobiotic metabolism and nitric oxide

Arnaud Tête , Isabelle Gallais , Muhammad Imran , Martine Chevanne , Marie Liamin et al.
Free Radical Biology and Medicine, 2018, 129, pp.323-337. ⟨10.1016/j.freeradbiomed.2018.09.042⟩
Journal articles hal-01888877v1