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authFullName_s : Nicolas Levoin

Synthesis and cytotoxicity studies of newly designed benzyl-hydroquinone derivatives

Olivier Tasseau , Paul Mosset , Sophie C Barillé-Nion , Fabien Gautier , Philippe Juin et al.
Medicinal Chemistry Research, 2018, 27 (4), pp.1050-1065. ⟨10.1007/s00044-017-2127-z⟩
Journal articles hal-01771097v1

Disrupting the CD95-PLC gamma 1 interaction prevents Th17-driven inflammation

Amanda Poissonnier , Jean-Philippe Guegan , Ha Thanh Nguyen , Daniel Best , Nicolas Levoin et al.
Nature Chemical Biology, 2018, 14 (12), pp.1079-+. ⟨10.1038/s41589-018-0162-9⟩
Journal articles hal-01976911v1
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Preliminary Studies on the Activity of Mixed Polyphenol-Heterocyclic Systems Against B16-F10 Melanoma Cancer Cells

Duc Duy Vo , Isabelle Rouaud , Françoise Lohézic-Le Dévéhat , Fabien Gautier , Sophie Barillé-Nion et al.
Medicinal Chemistry, 2016
Journal articles inserm-01406309v1

CD95-Mediated Calcium Signaling Promotes T Helper 17 Trafficking to Inflamed Organs in Lupus-Prone Mice

Amanda Poissonnier , Doriane Sanseau , Matthieu Le Gallo , Marine Malleter , Nicolas Levoin et al.
Immunity, 2016, 45 (1), pp.209--223. ⟨10.1016/j.immuni.2016.06.028⟩
Journal articles hal-01359568v1

Synthesis of peptidomimetics and chemo-biological tools for CD95/PLC gamma 1 interaction analysis

Ha Thanh Nguyen , Jean-Philippe Guégan , Amanda Poissonnier , Florence Jouan , Daniel Best et al.
Bioorganic and Medicinal Chemistry Letters, 2019, 29 (16), pp.2094-2099. ⟨10.1016/j.bmcl.2019.07.006⟩
Journal articles hal-02278513v1
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Discovery of potent dual ligands for dopamine D4 and σ1 receptors

Nicolas Levoin , A Murthy , Vennu Narendar , Nangunoori Sampath Kumar , Pasula Aparna et al.
Bioorganic and Medicinal Chemistry, 2022, 69, pp.116851. ⟨10.1016/j.bmc.2022.116851⟩
Journal articles hal-03716651v1

Probing the side chain tolerance for inhibitors of the CD95/PLCγ1 interaction

Ha Thanh Nguyen , Jean-Philippe Guegan , Daniel Best , Pierre van de Weghe , Nicolas Levoin et al.
Bioorganic and Medicinal Chemistry Letters, 2019, 29 (21), pp.126669. ⟨10.1016/j.bmcl.2019.126669⟩
Journal articles hal-02393634v1
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Structure Activity Relationship Studies around DB18, a Potent and Selective Inhibitor of CLK Kinases

Dabbugoddu Brahmaiah , Anagani Kanaka Durga Bhavani , Pasula Aparna , Nangunoori Sampath Kumar , Hélène Solhi et al.
Molecules, 2022, 27 (19), pp.6149. ⟨10.3390/molecules27196149⟩
Journal articles hal-03828358v1
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Structural revision of the Mcl-1 inhibitor MIM1: synthesis and biological studies on ovarian cancer cells with evaluation of designed analogues

Hippolyte Paysant , Siham Hedir , Frédéric Justaud , Louis Bastien Weiswald , Assaad Nasr El Dine et al.
Organic & Biomolecular Chemistry, 2021, 19 (41), pp.8968-8987. ⟨10.1039/d1ob01521d⟩
Journal articles hal-03414007v1
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Synthesis and biological studies of new piperidino-1,2,3-triazole hybrids with 3-aryl isoxazole side chains

Appala Venkata Ramana Murthy , Vennu Narendar , Nangunoori Sampath Kumar , Pasula Aparna , Anagani Kanaka Durga Bhavani et al.
Bioorganic & Medicinal Chemistry Letters, 2021, 52, pp.128390. ⟨10.1016/j.bmcl.2021.128390⟩
Journal articles hal-03414697v1
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MMP7 cleavage of amino-terminal CD95 death receptor switches signaling toward non-apoptotic pathways

Shoji F Kenji , Keerthi Kurma , Brigitte Collet , Christelle Oblet , Laure Debure et al.
Cell Death and Disease, 2022, 13 (10), pp.895. ⟨10.1038/s41419-022-05352-0⟩
Journal articles hal-03829415v1

Synthesis and evaluation of amides surrogates of dopamine D3 receptor ligands.

Mickael Jean , Jacques Renault , Nicolas Levoin , Denis Danvy , Thierry Calmels et al.
Bioorganic and Medicinal Chemistry Letters, 2010, 20 (18), pp.5376-9. ⟨10.1016/j.bmcl.2010.07.096⟩
Journal articles istex hal-00844473v1

Molecular tweezers: Synthesis and formation of host-guest complexes

Béatrice Legouin , Maud Gayral , Philippe Uriac , Jean-François Cupif , Nicolas Levoin et al.
European Journal of Organic Chemistry, 2010, 2010 (28), pp.5503-5508. ⟨10.1002/ejoc.201000729⟩
Journal articles istex hal-00844479v1

Synthesis of new mixed phenol/heterocyclic derivatives and studies of their activity as inhibitors of Bax/Bcl-xL interaction

Duc Duy Vo , Fabien Gautier , Sophie Barillé-Nion , Philippe Juin , Nicolas Levoin et al.
Tetrahedron, 2014, 70 (2), pp.301-311. ⟨10.1016/j.tet.2013.11.060⟩
Journal articles hal-01114411v1
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CD95 Structure, Aggregation and Cell Signaling

Nicolas Levoin , Mickael Jean , Patrick Legembre
Frontiers in Cell and Developmental Biology, 2020, 8, pp.314. ⟨10.3389/fcell.2020.00314⟩
Journal articles hal-02862235v1

Design, synthesis and biological evaluation of new inhibitors of Bax/Bcl-xL interaction in cancer cells.

Duc Duy Vo , Fabien Gautier , Sophie Barillé-Nion , Philippe Juin , Nicolas Levoin et al.
Bioorganic and Medicinal Chemistry Letters, 2014, 24 (7), pp.1758-61. ⟨10.1016/j.bmcl.2014.02.035⟩
Journal articles hal-01116303v1

Induction of intracellular calcium concentration by environmental benzo(a)pyrene involves a β2-adrenergic receptor/adenylyl cyclase/Epac-1/inositol 1,4,5-trisphosphate pathway in endothelial cells.

Abdullah Mayati , Nicolas Levoin , Hervé Paris , Monique N'Diaye , Arnaud Courtois et al.
Journal of Biological Chemistry, 2012, 287 (6), pp.4041-52. ⟨10.1074/jbc.M111.319970⟩
Journal articles hal-00682497v1
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Synthesis and biological evaluation of FJ-809, a compound originally described as MIM1 and inhibitor of the anti-apoptotic protein Mcl-1

Frédéric Justaud , Hippolyte Paysant , Louis Bastien Weiswald , Abdelghani Jebahi , Marie Jouanne et al.
New Journal of Chemistry, 2022, 46 (19), pp.9119-9127. ⟨10.1039/D1NJ05987D⟩
Journal articles hal-03713884v1

HIV Protease Inhibitors Cure Lupus-Prone Mice and Prevent T Helper 17 Cell-Driven Inflammation By Inhibiting CD95-Non-Apoptotic Signaling Pathway

Manon Charrier , Amanda Poissonnier , Daniel Best , Jean-Philippe Guégan , Nicolas Levoin et al.
Arthritis & rheumatology, 2018, 70 (suppl 10)
Journal articles hal-01940201v1
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Discovery of DB18, a potent inhibitor of CLK kinases with a high selectivity against DYRK1A kinase

Dabbugoddu Brahmaiah , Anagani Kanaka Durga Bhavani , Pasula Aparna , Nangunoori Sampath Kumar , Hélène Solhi et al.
Bioorganic and Medicinal Chemistry, 2021, 31, pp.115962. ⟨10.1016/j.bmc.2020.115962⟩
Journal articles hal-03128547v1

Corrigendum to “Synthesis of new mixed phenol/heterocyclic derivatives and studies of their activity as inhibitors of Bax/Bcl-xL interaction” [Tetrahedron 70 (2014) 301–311]

Duc Duy Vo , Fabien Gautier , Sophie Barillé-Nion , Philippe Juin , Nicolas Levoin et al.
Tetrahedron, 2014, 70 (33), pp.4977. ⟨10.1016/j.tet.2014.05.062⟩
Journal articles hal-01153823v1

The Prins reaction using ketones: rationalization and application toward the synthesis of the portentol skeleton.

Maiwenn Jacolot , Mickael Jean , Pierre van de Weghe , Nicolas Levoin
Organic Letters, 2012, 14 (1), pp.58-61. ⟨10.1021/ol202829u⟩
Journal articles hal-00841525v1
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A combination of in-silico and SAR studies to identify binding hot spots of Bcl-xL inhibitors

Nicolas Levoin , Duc Duy Vo , Fabien Gautier , Sophie Barillé-Nion , Philippe Juin et al.
Bioorganic and Medicinal Chemistry, 2015, 23 (8), pp.1747-1757. ⟨10.1016/j.bmc.2015.02.060⟩
Journal articles hal-01133213v1