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authFullName_s : Myriam Le Roch

Gold-mediated synthesis and functionalization of chiral halopyridones.

Khanh Hung Nguyen , Sophie Tomasi , Myriam Le Roch , Loïc Toupet , Jacques Renault et al.
Journal of Organic Chemistry, 2013, 78 (16), pp.7809-15. ⟨10.1021/jo400827b⟩
Journal articles hal-00866844v1

Integrating targeted gene expression and a skin model system to identify functional inhibitors of the UV activated p38 MAP kinase

Amaal Abrahams , Nicolas Mouchet , Nicolas Gouault , Françoise Lohézic-Le Dévéhat , Myriam Le Roch et al.
Photochemical & Photobiological Sciences , 2016, 15 (12), pp.1468-1475. ⟨10.1039/c6pp00283h⟩
Journal articles hal-01439371v1

Enantiospecific synthesis of pyridinones as versatile intermediates toward asymmetric piperidines.

Nicolas Gouault , Myriam Le Roch , Adèle Cheignon , Philippe Uriac , Michèle David et al.
Organic Letters, 2011, 13 (16), pp.4371-3. ⟨10.1021/ol201698m⟩
Journal articles hal-00843472v1

On the formation of a protic ionic liquid in nature.

Li Chen , Genevieve E Mullen , Myriam Le Roch , Cody G Cassity , Nicolas Gouault et al.
Angewandte Chemie International Edition, 2014, 53 (44), pp.11762-5. ⟨10.1002/anie.201404402⟩
Journal articles istex hal-01116159v1
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Structure simplification of the Securinine skeleton reveals the importance of BCD ring system for the cytotoxic activity on HCT116 and HL60 cell lines

Myriam Le Roch , Damien Afonso , Egor Chirkin , Xavier Guillory , François-Hugues Porée et al.
Bioorganic and Medicinal Chemistry, 2022, 58, pp.116658. ⟨10.1016/j.bmc.2022.116658⟩
Journal articles hal-03683055v1

Total synthesis of dendrobate alkaloid (+)-241D, isosolenopsin and isosolenopsin A: application of a gold-catalyzed cyclization.

Nicolas Gouault , Myriam Le Roch , Gisele de Campos Pinto , Michèle David
Organic & Biomolecular Chemistry, 2012, 10 (29), pp.5541-6. ⟨10.1039/c2ob25685a⟩
Journal articles hal-00841675v1
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Gold-Catalyzed Synthesis of Substituted 3-Trifluoromethylpyrroles from Mesylated Amino Trifluoromethylpropargylic Alcohols

Benjamin Guieu , Myriam Le Roch , Michèle David , Nicolas Gouault
Journal of Organic Chemistry, 2017, 82 (24), pp.13708-13713. ⟨10.1021/acs.joc.7b02567⟩
Journal articles hal-01680989v1

Targeting the polyamine transport system with benzazepine- and azepine-polyamine conjugates.

Sophie Tomasi , Jacques Renault , Bénédicte Martin , Stephane Duhieu , Virginie Cerec et al.
Journal of Medicinal Chemistry, 2010, 53 (21), pp.7647-63. ⟨10.1021/jm1007648⟩
Journal articles hal-00752582v1
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Gold-catalyzed synthesis of enantioenriched furfurylamines from amino acids

Benjamin Guieu , Myriam Le Roch , Michèle David , Nicolas Gouault
Tetrahedron: Asymmetry, 2015, 26 (15–16), pp.868--875. ⟨10.1016/j.tetasy.2015.06.014⟩
Journal articles hal-01188233v1