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authFullName_s : Mickael Jean

Synthesis of peptidomimetics and chemo-biological tools for CD95/PLC gamma 1 interaction analysis

Ha Thanh Nguyen , Jean-Philippe Guégan , Amanda Poissonnier , Florence Jouan , Daniel Best et al.
Bioorganic and Medicinal Chemistry Letters, 2019, 29 (16), pp.2094-2099. ⟨10.1016/j.bmcl.2019.07.006⟩
Journal articles hal-02278513v1

Transition metal C-H activation: application to stereoselective synthesis of natural products and drugs

Mickael Jean , Pierre van de Weghe
Stereoselective Synthesis of Drugs and Natural Products, Wiley, pp.667-686, 2013, 978-1-118-03217-6
Book sections hal-00868413v1

Probing the side chain tolerance for inhibitors of the CD95/PLCγ1 interaction

Ha Thanh Nguyen , Jean-Philippe Guegan , Daniel Best , Pierre van de Weghe , Nicolas Levoin et al.
Bioorganic and Medicinal Chemistry Letters, 2019, 29 (21), pp.126669. ⟨10.1016/j.bmcl.2019.126669⟩
Journal articles hal-02393634v1

Gold-catalyzed C-S Bond Formation from Thiols

Mickael Jean , Jacques Renault , Pierre van de Weghe , Naoki Asao
Tetrahedron Letters, 2010, 51 (2), pp.378-381. ⟨10.1016/j.tetlet.2009.11.025⟩
Journal articles istex hal-00844444v1

Correction to A Novel Covalent mTOR Inhibitor, DHM25, Shows in Vivo Antitumor Activity against Triple-Negative Breast Cancer Cells

Amélie Fouqué , Olivier Delalande , Mickael Jean , Rémy Castellano , Emmanuelle Josselin et al.
Journal of Medicinal Chemistry, 2019, 62 (20), pp.9339-9340. ⟨10.1021/acs.jmedchem.9b01578⟩
Journal articles hal-02526957v1
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Role of metalloproteases in the CD95 signaling pathways

Laurent Devel , Nicolas Guedeney , Sarah Bregant , Animesh Chowdhury , Mickael Jean et al.
Frontiers in Immunology, 2022, 13, pp.1074099. ⟨10.3389/fimmu.2022.1074099⟩
Journal articles hal-03924572v1
Image document

Synthesis of new bioisosteric hemiasterlin analogues with extremely high cytotoxicity

Chinh Pham The , Tuyet Anh Dang Thi , Thi Phuong Hoang , Quoc Anh Ngo , Duy Tien Doan et al.
Bioorganic and Medicinal Chemistry Letters, 2014, 24 (22), pp.5216-5218. ⟨10.1016/j.bmcl.2014.09.065⟩
Journal articles hal-01080910v1
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Synthesis and evaluation of 1,3,4-oxadiazole derivatives for development as broad-spectrum antibiotics

Cédric Tresse , Richard Radigue , Rafael Gomes von Borowski , Marion Thepaut , Hong Hanh Le et al.
Bioorganic and Medicinal Chemistry, 2019, 27 (21), pp.115097. ⟨10.1016/j.bmc.2019.115097⟩
Journal articles hal-02304766v1
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Investigation of Phospholipase Cγ1 Interaction with SLP76 Using Molecular Modeling Methods for Identifying Novel Inhibitors

Neha Tripathi , Iyanar Vetrivel , Stéphane Téletchéa , Mickael Jean , Patrick Legembre et al.
International Journal of Molecular Sciences, 2019, 20 (19), pp.E4721. ⟨10.3390/ijms20194721⟩
Journal articles hal-02307452v1

Synthesis of stachybotrin C and all of its stereoisomers: structure revision.

Maiwenn Jacolot , Mickael Jean , Naresh Tumma , Arnaud Bondon , Srivari Chandrasekhar et al.
Journal of Organic Chemistry, 2013, 78 (14), pp.7169-75. ⟨10.1021/jo401116r⟩
Journal articles hal-00862776v1

Synthetic studies towards Stachybotrin C

Naresh Tumma , Maiwenn Jacolot , Mickael Jean , Srivari Chandrasekhar , Pierre van de Weghe et al.
SYNLETT, 2012, 23 (20), pp.2919-2922. ⟨10.1055/s-0032-1317528⟩
Journal articles hal-00841803v1

Gold-catalyzed intramolecular hydroarylation of olefins. Scope evaluation and preliminary mechanistic studies

Mickael Jean , Pierre van de Weghe
Tetrahedron Letters, 2011, 52 (27), pp.3509-3513. ⟨10.1016/j.tetlet.2011.04.122⟩
Journal articles istex hal-00843552v1

Disrupting the CD95-PLC gamma 1 interaction prevents Th17-driven inflammation

Amanda Poissonnier , Jean-Philippe Guegan , Ha Thanh Nguyen , Daniel Best , Nicolas Levoin et al.
Nature Chemical Biology, 2018, 14 (12), pp.1079-+. ⟨10.1038/s41589-018-0162-9⟩
Journal articles hal-01976911v1

New pi3k​/akt​/mtor inhibitors and pharmaceutical uses thereof

Mickael Jean , Amelie Fouque , Patrick Legembre , Pierre van de Weghe
France, Patent n° : WO 2015044229 / EP 2853530. 2015
Patents hal-01139914v1

Quinolines derivatives as promising new antifungal candidates for the treatment of candidiasis and dermatophytosis

Gabriella da Rosa Monte Machado , Denise Diedrich , Thaís Carine Ruaro , Aline Rigon Zimmer , Mário Lettieri Teixeira et al.
Brazilian Journal of Microbiology, 2020, 51 (4), pp.1691-1701. ⟨10.1007/s42770-020-00348-4⟩
Journal articles hal-04022492v1

A Novel Covalent mTOR Inhibitor, DHM25, Shows in Vivo Antitumor Activity against Triple-Negative Breast Cancer Cells

Amelie Fouque , Olivier Delalande , Mickael Jean , Remy Castellano , Emmanuelle Josselin et al.
Journal of Medicinal Chemistry, 2015, 58 (16), pp.6559-6573. ⟨10.1021/acs.jmedchem.5b00991⟩
Journal articles hal-01187307v1
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MMP7 cleavage of amino-terminal CD95 death receptor switches signaling toward non-apoptotic pathways

Shoji F Kenji , Keerthi Kurma , Brigitte Collet , Christelle Oblet , Laure Debure et al.
Cell Death and Disease, 2022, 13 (10), pp.895. ⟨10.1038/s41419-022-05352-0⟩
Journal articles hal-03829415v1

Synthesis and evaluation of amides surrogates of dopamine D3 receptor ligands.

Mickael Jean , Jacques Renault , Nicolas Levoin , Denis Danvy , Thierry Calmels et al.
Bioorganic and Medicinal Chemistry Letters, 2010, 20 (18), pp.5376-9. ⟨10.1016/j.bmcl.2010.07.096⟩
Journal articles istex hal-00844473v1

Synthesis of Stachybotrin C

Mickael Jean
8th IFCOS-CEFISO meeting, Goa, 1st-3rd April 2013, Apr 2013, France
Conference papers hal-00872269v1
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Soluble CD95L in cancers and chronic inflammatory disorders, a new therapeutic target?

Keerthi Kurma , Andrea Boizard-Moracchini , Gael Galli , Mickael Jean , Pierre Vacher et al.
Biochimica et Biophysica Acta (BBA) - Reviews on Cancer, 2021, 1876 (2), pp.188596. ⟨10.1016/j.bbcan.2021.188596⟩
Journal articles hal-03333846v1
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CD95 Structure, Aggregation and Cell Signaling

Nicolas Levoin , Mickael Jean , Patrick Legembre
Frontiers in Cell and Developmental Biology, 2020, 8, pp.314. ⟨10.3389/fcell.2020.00314⟩
Journal articles hal-02862235v1

HIV Protease Inhibitors Cure Lupus-Prone Mice and Prevent T Helper 17 Cell-Driven Inflammation By Inhibiting CD95-Non-Apoptotic Signaling Pathway

Manon Charrier , Amanda Poissonnier , Daniel Best , Jean-Philippe Guégan , Nicolas Levoin et al.
Arthritis & rheumatology, 2018, 70 (suppl 10)
Journal articles hal-01940201v1

The Prins reaction using ketones: rationalization and application toward the synthesis of the portentol skeleton.

Maiwenn Jacolot , Mickael Jean , Pierre van de Weghe , Nicolas Levoin
Organic Letters, 2012, 14 (1), pp.58-61. ⟨10.1021/ol202829u⟩
Journal articles hal-00841525v1

Ex vivo potential of a quinoline-derivative nail lacquer as a new alternative for dermatophytic onychomycosis treatment

Gabriella da Rosa Monte Machado , Bruna Pippi , Simone Berlitz , Denise Diedrich , Diego Defferrari et al.
Journal of Medical Microbiology, 2021, 70 (3), ⟨10.1099/jmm.0.001314⟩
Journal articles hal-03128571v1