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authFullName_s : Jean-Pierre Bazureau
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Encapsulation of (E)-N’-(1-(7-(diethylamino)-2-oxo-2H-chromen-3 yl)ethylidene)benzohydrazide (7-diEAHC) in β-cyclodextrins: Optimized synthesis of 7-diEACH and in silico ADME profiling, physical stability, antioxidant properties of encapsulated 7-diEAHC and bioavailability in rats

E. Khdhiri , S Abid , K. Athmouni , M. Abid , H. Ayadi et al.
Results in Chemistry, 2023, 5, pp.100681. ⟨10.1016/j.rechem.2022.100681⟩
Journal articles hal-03975255v1
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Sample preparation for an optimized extraction of localized metabolites in lichens: Application to Pseudevernia furfuracea

Sarah Komaty , Marine Letertre , Huyen Duong Dang , Harald Jungnickel , Peter Laux et al.
Talanta, 2016, 150, pp.525-530. ⟨10.1016/j.talanta.2015.12.081⟩
Journal articles hal-01254800v1
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A Practical Approach to New (5Z) 2-Alkylthio-5-arylmethylene- 1-methyl-1,5-dihydro-4H-imidazol-4-one Derivatives

Khadidja Bourahla , Ludovic Paquin , Olivier Lozach , Laurent Meijer , François Carreaux et al.
Molecules, 2011, 16, pp.7377-7390. ⟨10.3390/molecules16097377⟩
Journal articles hal-00870301v1

Ionic liquid-phase organic synthesis (IoLiPOS) methodology applied to cross aldol reaction

Halima Hakkou , Daniel Carrié , Ludovic Paquin , Jean-Pierre Bazureau
Russian Journal of Organic Chemistry / Zhurnal Organicheskoi Khimii, 2011, 47 (3), pp.371-373. ⟨10.1134/S1070428011030079⟩
Journal articles istex hal-00869914v1

Microwave synthesis of new 3-(3-aminopropyl)-5-arylidene-2-thioxo-1,3-thiazolidine-4-ones as potential Ser/Thr protein kinase inhibitors

Camille Déliko Dago , Wacothon Karime Coulibaly , Yves-Alain Bekro , Janat A. Mamyrbekova-Bekro , Beatrice Foll-Josselin et al.
Medicinal Chemistry Research, 2016, 25 (12), pp.2940--2958. ⟨10.1007/s00044-016-1719-3⟩
Journal articles hal-01414293v1
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Evolution of DMSP (dimethylsulfoniopropionate) biosynthesis pathway: Origin and phylogenetic distribution in polyploid Spartina (Poaceae, Chloridoideae)

Hélène Rousseau , Mathieu Rousseau-Gueutin , Xavier Dauvergne , Julien Boutte , Gaëlle Simon et al.
Molecular Phylogenetics and Evolution, 2017, 114, pp.401-414. ⟨10.1016/j.ympev.2017.07.003⟩
Journal articles hal-01579439v1

Selectivity, cocrystal structures, and neuroprotective properties of leucettines, a family of protein kinase inhibitors derived from the marine sponge alkaloid leucettamine B.

Tania Tahtouh , Jonathan M. Elkins , Panagis Filippakopoulos , Meera Soundararajan , Guillaume Burgy et al.
Journal of Medicinal Chemistry, 2012, 55 (21), pp.9312-30. ⟨10.1021/jm301034u⟩
Journal articles hal-00870472v1

Investigation on the synthesis of new 3-[4-(arylalkoxy)phenylethyl]-2-thioxo-1,3-thiazolidin-4-ones and their biological evaluation against cancer cells

Camille Déliko Dago , Christelle N'Ta Ambeu , Wacothon Karime Coulibaly , Yves-Alain Békro , Janat A. Mamyrbekova-Bekro et al.
Chemistry of Heterocyclic Compounds, 2017, 53 (3), pp.341--349. ⟨10.1007/s10593-017-2056-2⟩
Journal articles hal-01586061v1

Method for synthesizing polyesters in an acidic ionic liquid medium

Alain Fradet , Hervé Lefebvre , Jean-Pierre Bazureau , Ludovic Paquin , Daniel Carrié et al.
France, Patent n° : WO2011012814 A1. 2011
Patents hal-00873181v1

Synthesis and preliminary biological evaluation of new derivatives of the marine alkaloid leucettamine B as kinase inhibitors.

Mansour Debdab , Stéven Renault , Olivier Lozach , Laurent Meijer , Ludovic Paquin et al.
European Journal of Medicinal Chemistry, 2010, 45 (2), pp.805-10. ⟨10.1016/j.ejmech.2009.10.009⟩
Journal articles istex hal-00869769v1

Synthesis of 3,5-disubstituted 1,2,4-oxadiazoles using ionic liquid-phase organic synthesis (IoLiPOS) methodology

Laetitia Duchet , Jean-Christophe Legeay , Daniel Carrié , Ludovic Paquin , Jean-Jacques Vanden et al.
Tetrahedron, 2010, 66 (4), pp.986-994. ⟨10.1016/j.tet.2009.11.079⟩
Journal articles istex hal-00869781v1
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The Franco-Brazilian network on natural products (FB2NP): a new network promoting cooperation and exchanges in natural products research

Jackson Almeida , Raphaël Grougnet , Lucindo Quintans , Marc Feuilloley , Thomas Robert et al.
Journal articles hal-03592226v1
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N-Boc and N-CBz Ethyl Oxamates: New Gabriel Reagents

Fabienne Berrée , Jean-Pierre Bazureau , Gwendal Michelot , Maurice Le Cone
Synthetic Communications, 1999, 29 (15), pp.2685-2693. ⟨10.1080/00397919908086430⟩
Journal articles hal-03985910v1
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Studies of the Chemical Reactivity of a Series of Rhodanine Derivatives by Approaches to Quantum Chemistry

Wacothon Karime Coulibaly , Jean Stéphane N’dri , Mamadou Guy-Richard Koné , Camille Déliko Dago , Christelle N’ta Ambeu et al.
Computational Molecular Bioscience, 2019, 09 (03), pp.49-62. ⟨10.4236/cmb.2019.93005⟩
Journal articles hal-02572308v1

Microwave Assisted Organic Synthesis (MAOS) of New Dispacamide A Derivatives Bearing a Thiazolinone Platform, Biological Assays on Inhibition of Protein Kinases and Cell Effects

Solene Guiheneuf , Ludovic Paquin , Francois Carreaux , Emilie Durieu , Helene Benedetti et al.
Current microwave chemistry, 2014, 1 (1), pp.33-40. ⟨10.2174/22133356114019990002⟩
Journal articles hal-01114583v1
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30th Franco-Belgian conference of pharmacochemistry

Charlotte Bouckaert , Eric Goffin , Sebastien Dilly , Julien Hanson , Lionel Pochet et al.
Pharmaceuticals, 2016, 9 (4), pp.73. ⟨10.3390/ph9040073⟩
Journal articles hal-02141338v1
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1,3-dipolar cycloadditions of aldehydes or Imines with carbonyl ylides generated from epoxides: Classical heating and microwave irradiation

Ghenia Bentabed-Ababsa , Mustapha Rahmouni , Florence Mongin , Aicha Derdour , Jack. Hamelin et al.
Synthetic Communications, 2007, 37 (17), pp.2935-2948. ⟨10.1080/07370650701471699⟩
Journal articles hal-00781884v1
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Practical approach to N-benzyl derivatives of 2-amino-8-methoxy-4H-chromene-3-carbonitrile by reductive amination: Exploration of their effects against protein kinases and in silico ADME profiling

Marwa Dhiabi , Ali Bouattour , Mehdi Fakhfakh , Souhir Abid , Ludovic Paquin et al.
Journal of Molecular Structure, 2023, 1274 (Part 1), pp.134319. ⟨10.1016/j.molstruc.2022.134319⟩
Journal articles hal-03867314v1

Leucettines, a class of potent inhibitors of cdc2-like kinases and dual specificity, tyrosine phosphorylation regulated kinases derived from the marine sponge leucettamine B: modulation of alternative pre-RNA splicing.

Mansour Debdab , François Carreaux , Steven Renault , Meera Soundararajan , Oleg Fedorov et al.
Journal of Medicinal Chemistry, 2011, 54 (12), pp.4172-86. ⟨10.1021/jm200274d⟩
Journal articles hal-00870007v1

An efficient approach to dispacamide A and its derivatives.

Solène Guihéneuf , Ludovic Paquin , François Carreaux , Emilie Durieu , Laurent Meijer et al.
Organic & Biomolecular Chemistry, 2012, 10 (5), pp.978-87. ⟨10.1039/c1ob06161e⟩
Journal articles hal-00870469v1
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(E)-N'-(1-(3-oxo-3H-benzo[f]chromen-2-yl)ethylidene)benzohydrazide protecting rat heart tissues from isoproterenol toxicity: Evidence from in vitro and in vivo tests

Khdhiri Emna , Kais Mnafgui , Lakhdar Ghazouani , Anouar Feriani , Raouf Hajji et al.
European Journal of Pharmacology, 2020, 881, pp.173137. ⟨10.1016/j.ejphar.2020.173137⟩
Journal articles hal-02635141v1

cdc-like/dual-specificity tyrosine phosphorylation-regulated kinases inhibitor leucettine L41 induces mTOR-dependent autophagy: implication for Alzheimer's disease.

Xavier Fant , Emilie Durieu , Gaëtan Chicanne , Bernard Payrastre , Diego Sbrissa et al.
Molecular Pharmacology, 2014, 85 (3), pp.441-50. ⟨10.1124/mol.113.090837⟩
Journal articles inserm-01012086v1
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Reactivity Under Microwave Irradiation of 2-amino 4H-chromene-3-carbonitrile as tool for the construction of potential bioactive derivatives

Ali Bouattour , Mehdi Fakhfakh , Houcine Ammar , Ludovic Paquin , Jean-Pierre Bazureau et al.
3rd International Electronic Conference on Medicinal Chemistry, Nov 2022, Online, France
Conference papers hal-03872422v1

Structure-Activity Relationship in the Leucettine Family of Kinase Inhibitors

Tania Tahtouh , Emilie Durieu , Benoit Villiers , Celine Bruyere , Thu Lan Nguyen et al.
Journal of Medicinal Chemistry, 2022, 65 (2), pp.1396-1417. ⟨10.1021/acs.jmedchem.1c01141⟩
Journal articles hal-03512536v1
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Marine-Derived 2-Aminoimidazolone Alkaloids. Leucettamine B-Related Polyandrocarpamines Inhibit Mammalian and Protozoan DYRK & CLK Kinases

Nadège Loaëc , Eletta Attanasio , Benoît Villiers , Emilie Durieu , Tania Tahtouh et al.
Marine drugs, 2017, 15 (10), pp.316 -. ⟨10.3390/md15100316⟩
Journal articles hal-01640115v1
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A practical multi-step synthesis of ethyl N-functionalized β-amino benzimidazole acrylate derivatives as promising cytotoxic agents

Christelle N'Ta Ambeu , Rémy Le Guével , Anne Corlu , Janat Akhanovna Mamyrbekova , Jean-Pierre Bazureau et al.
Molecular Diversity, 2018, 22 (3), pp.685-708. ⟨10.1007/s11030-018-9824-5⟩
Journal articles hal-01808102v1
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Leucettine L41, a DYRK1A-preferential DYRKs/CLKs inhibitor, prevents memory impairments and neurotoxicity induced by oligomeric Aβ25-35 peptide administration in mice.

Gaëlle Naert , Valentine Ferré , Johann Meunier , Emeline Keller , Susanna Malmstrom et al.
European Neuropsychopharmacology, 2015, 25 (11), pp.2170-2182. ⟨10.1016/j.euroneuro.2015.03.018⟩
Journal articles hal-01146496v1
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Synthetic Development of New 3-(4-Arylmethylamino)butyl-5-arylidene-rhodanines under Microwave Irradiation and Their Effects on Tumor Cell Lines and against Protein Kinases

Camille Déliko Dago , Christelle Ambeu , Wacothon-Karime Coulibaly , Yves-Alain Békro , Janat Mamyrbékova et al.
Molecules, 2015, 20 (7), pp.12412-12435. ⟨10.3390/molecules200712412⟩
Journal articles hal-01187427v1
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Anti-proliferative Activity Study on 5-Arylidene Rhodanine Derivatives Using Density Functional Theory (DFT) and Quantitative Structure Activity Relationship (QSAR)

Wacothon Coulibaly , Affi Sopi , James Titah , Guy-Richard Koné , Affoué Estelle et al.
International Journal of Computational and Theoretical Chemistry, 2022, ⟨10.11648/j.ijctc.20221001.11⟩
Journal articles hal-03988161v1
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Correction of cognitive deficits in mouse models of Down syndrome by a pharmacological inhibitor of DYRK1A

Thu Lan Nguyen , Arnaud Duchon , Antigoni Manousopoulou , Nadège Loaëc , Benoît Villiers et al.
Disease Models & Mechanisms, 2018, 11 (9), pp.dmm035634. ⟨10.1242/dmm.035634⟩
Journal articles hal-01862465v1