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authFullName_s : Jean-François Arnal
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Nuclear translocation of MRTFA in MCF7 breast cancer cells shifts ERα nuclear/genomic to extra-nuclear/non genomic actions

Charly Jehanno , Frédéric Percevault , Noureddine Boujrad , Pascale Le Goff , Coralie Fontaine et al.
Molecular and Cellular Endocrinology, 2021, 530, pp.111282. ⟨10.1016/j.mce.2021.111282⟩
Journal articles hal-03221142v1
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The tissue-specific effects of different 17β-estradiol doses reveal the key sensitizing role of AF1 domain in ERα activity

Coralie Fontaine , Melissa Buscato , Alexia Vinel , Frank Giton , Isabelle Raymond-Letron et al.
Molecular and Cellular Endocrinology, 2020, 505, pp.110741. ⟨10.1016/j.mce.2020.110741⟩
Journal articles hal-02470890v1

The transactivating function 1 of estrogen receptor alpha is dispensable for the vasculoprotective actions of 17beta-estradiol.

Audrey Billon-Galés , Coralie Fontaine , Cédric Filipe , Victorine Douin-Echinard , Marie-José Fouque et al.
Proceedings of the National Academy of Sciences of the United States of America, 2009, 106 (6), pp.2053-8. ⟨10.1073/pnas.0808742106⟩
Journal articles hal-00369691v1
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Changes in Gene Expression and Estrogen Receptor Cistrome in Mouse Liver Upon Acute E2 Treatment

Gaëlle Palierne , Aurelie J Fabre , Romain Solinhac , Christine Le Peron , Stéphane Avner et al.
Molecular Endocrinology -Baltimore-, 2016, 30 (7), pp.709-732. ⟨10.1210/me.2015-1311⟩
Journal articles hal-01357623v1

The uterine and vascular actions of estetrol delineate a distinctive profile of estrogen receptor α modulation, uncoupling nuclear and membrane activation.

Anne Abot , Coralie Fontaine , Mélissa Buscato , Romain Solinhac , Gilles Flouriot et al.
EMBO Molecular Medicine, 2014, 6 (10), pp.1328-46. ⟨10.15252/emmm.201404112⟩
Journal articles hal-01118028v1
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The antagonist properties of Bazedoxifene after acute treatment are shifted to stimulatory action after chronic exposure in the liver but not in the uterus

Mélissa Buscato , Coralie Fontaine , Aurélie Fabre , Alexia Vinel , Marie-Cécile Valera et al.
Molecular and Cellular Endocrinology, 2018, 472 (472), pp.87-96. ⟨10.1016/j.mce.2017.11.022⟩
Journal articles hal-01812522v1

From in vivo gene targeting of Estrogen Receptors to Optimisation of their Modulation in Menopause.

Jean-François Arnal , Françoise Lenfant , Gilles Flouriot , Florence Tremollières , Henrik Laurell et al.
British Journal of Pharmacology, 2011, 165 (1), pp.57-66. ⟨10.1111/j.1476-5381.2011.01538.x⟩
Journal articles inserm-00615516v1
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The AF-1-deficient estrogen receptor ERα46 isoform is frequently expressed in human breast tumors

Elodie Chantalat , Frédéric Boudou , Henrik Laurell , Gaëlle Palierne , René Houtman et al.
Breast Cancer Research, 2016, 18 (1), pp.123. ⟨10.1186/s13058-016-0780-7⟩
Journal articles inserm-01412032v1

Membrane and Nuclear Estrogen Receptor Alpha Actions: From Tissue Specificity to Medical Implications

Jean-François Arnal , Françoise Lenfant , Raphaël Métivier , Gilles Flouriot , Daniel Henrion et al.
Physiological Reviews, 2017, 97 (3), pp.1045-1087. ⟨10.1152/physrev.00024.2016⟩
Journal articles hal-01533249v1

Tamoxifen elicits atheroprotection through estrogen receptor α AF-1 but does not accelerate reendothelialization.

Coralie Fontaine , Anne Abot , Audrey Billon-Galés , Gilles Flouriot , Hortense Bergès et al.
American Journal of Pathology, 2013, 183 (1), pp.304-12. ⟨10.1016/j.ajpath.2013.03.010⟩
Journal articles hal-00874317v1

Activation function 2 (AF2) of estrogen receptor-{alpha} is required for the atheroprotective action of estradiol but not to accelerate endothelial healing.

Audrey Billon-Galés , Andrée Krust , Coralie Fontaine , Anne Abot , Gilles Flouriot et al.
Proceedings of the National Academy of Sciences of the United States of America, 2011, 108 (32), pp.13311-6. ⟨10.1073/pnas.1105632108⟩
Journal articles inserm-00615519v1

The AF-1 activation function of estrogen receptor α is necessary and sufficient for uterine epithelial cell proliferation in vivo.

Anne Abot , Coralie Fontaine , Isabelle Raymond-Letron , Gilles Flouriot , Marine Adlanmerini et al.
Endocrinology, 2013, 154 (6), pp.2222-33. ⟨10.1210/en.2012-2059⟩
Journal articles inserm-00851701v1
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Tamoxifen Accelerates Endothelial Healing by Targeting ERα in Smooth Muscle Cells

Rana Zahreddine , Morgane Davezac , Natalia Smirnova , Melissa Buscato , Emeline Lhuillier et al.
Circulation Research, 2020, 127 (12), pp.1473-1487. ⟨10.1161/CIRCRESAHA.120.317062⟩
Journal articles hal-03040722v1
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Selective Liver Estrogen Receptor Modulation Prevents Steatosis, Diabetes, and Obesity Through the Anorectic Growth Differentiation Factor 15 Hepatokine in Mice

Maeva Guillaume , Elodie Riant , Aurelie Fabre , Isabelle Raymond-Letron , Melissa Buscato et al.
Hepatology Communications, 2019, 3 (7), pp.908-924. ⟨10.1002/hep4.1363⟩
Journal articles hal-02277993v1

Repression of the estrogen receptor-alpha transcriptional activity by the Rho/megakaryoblastic leukemia 1 signaling pathway.

Guillaume Huet , Yohann Mérot , Frédéric Percevault , Christophe Tiffoche , Jean-François Arnal et al.
Journal of Biological Chemistry, 2009, 284 (49), pp.33729-39. ⟨10.1074/jbc.M109.045534⟩
Journal articles inserm-00426655v1
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Integrative study of diet-induced mouse models of NAFLD identifies PPARα as a sexually dimorphic drug target

Sarra Smati , Arnaud Polizzi , Anne Fougerat , Sandrine Ellero-Simatos , Yuna Blum et al.
Gut, 2022, 71 (4), pp.807-821. ⟨10.1136/gutjnl-2020-323323⟩
Journal articles hal-03215969v1

0218: The uterine and vascular actions of estetrol delineate an original distinctive profile of estrogen receptor α modulation, uncoupling nuclear and membrane activation

Coralie Fontaine , Anne Abot , Romain Solinhac , Anne Drougard , Aurelie J Fabre et al.
Printemps de la Cardiologie, Apr 2014, Strasbourg, France. pp.8, ⟨10.1016/S1878-6480(14)71283-2⟩
Conference papers hal-01118035v1