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authFullName_s : Jørn A. Holme

Signalling pathways involved in 1-nitropyrene (1-NP)-induced and 3-nitrofluoranthene (3-NF)-induced cell death in Hepa1c1c7 cells.

Nana Asare , Xavier Tekpli , Mary Rissel , Anita Solhaug , Nina Landvik et al.
Mutagenesis, 2009, 24 (6), pp.481-93. ⟨10.1093/mutage/gep032⟩
Journal articles hal-00696160v1

Mechanisms involved in lipid accumulation and apoptosis induced by 1-nitropyrene in Hepa1c1c7 cells.

Normand Podechard , Xavier Tekpli , Daniel D. Catheline , Jørn A. Holme , Vincent V. Rioux et al.
Toxicology Letters, 2011, 206 (3), pp.289-99. ⟨10.1016/j.toxlet.2011.07.024⟩
Journal articles istex hal-00682029v1
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Different mechanisms involved in apoptosis following exposure to benzo[a]pyrene in F258 and Hepa1c1c7 cells.

Jørn A. Holme , Morgane Gorria , Volker M. Arlt , Steinar Ovrebø , Anita Solhaug et al.
Chemico-Biological Interactions, 2007, 167 (1), pp.41-55. ⟨10.1016/j.cbi.2007.01.008⟩
Journal articles hal-00690306v1

3-nitrofluoranthene (3-NF)-induced apoptosis and programmed necrosis.

Nana Asare , Dominique Lagadic-Gossmann , Jørn A. Holme
Autophagy, 2009, 5 (5), pp.751-2. ⟨10.4161/auto.5.5.8790⟩
Journal articles hal-00674462v1

Membrane remodeling, an early event in benzo[a]pyrene-induced apoptosis.

Xavier Tekpli , Mary Rissel , Laurence Huc , Daniel D. Catheline , Odile Sergent et al.
Toxicology and Applied Pharmacology, 2010, 243 (1), pp.68-76. ⟨10.1016/j.taap.2009.11.014⟩
Journal articles istex hal-00660136v1
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Identification of the couple GSK3α/c-Myc as a new regulator of hexokinase II in benzo[a]pyrene-induced apoptosis.

Béatrice Dendelé , Xavier Tekpli , Odile Sergent , Marie-Thérèse Dimanche-Boitrel , Jørn A. Holme et al.
Toxicology in Vitro, 2012, 26 (1), pp.94-101. ⟨10.1016/j.tiv.2011.11.001⟩
Journal articles hal-00682104v1

1-Nitropyrene (1-NP) induces apoptosis and apparently a non-apoptotic programmed cell death (paraptosis) in Hepa1c1c7 cells.

Nana Asare , Nina E. Landvik , Dominique Lagadic-Gossmann , Mary Rissel , Xavier Tekpli et al.
Toxicology and Applied Pharmacology, 2008, 230 (2), pp.175-86. ⟨10.1016/j.taap.2008.02.015⟩
Journal articles hal-00674320v1

Carcinogen-induced lipid membrane remodelling is essential for the NHE-1 activation involved in related apoptosis

Xavier Tekpli , Béatrice Dendelé , Laure Debure , Odile Sergent , Maryvonne Rissel et al.
2nd International Meeting 2010 "Ion channels and Cancer", Mar 2010, Florence, Italy
Conference papers hal-00675245v1

3-Nitrofluoranthene (3-NF) but not 3-aminofluoranthene (3-AF) elicits apoptosis as well as programmed necrosis in Hepa1c1c7 cells.

Nana Asare , Marit Låg , Dominique Lagadic-Gossmann , Mary Rissel , Per Schwarze et al.
Toxicology, 2009, 255 (3), pp.140-50. ⟨10.1016/j.tox.2008.10.021⟩
Journal articles istex hal-00674455v1

Hexokinase II: a key NHE1- and p53-regulated protein in benzo[a]pyrene-induced apoptosis.

Laurence Huc , Xavier Tekpli , Jørn A. Holme , Anita Solhaug , Morgane Gorria et al.
The 12th World Congress on Advances in Oncology and 10th International Symposium on Molecular Medicine, Oct 2007, Crète, Greece. pp.S40
Conference papers hal-00690394v1

Mechanisms of benzo[a]pyrene induced cell death: possible implications for mutagenesis

Jørn A. Holme , Xavier Tekpli , Edgar Rivedal , Nana Asare , Nina Landvik et al.
EEMS-2008-meeting, Sep 2008, Dubrovnik, Croatia
Conference papers hal-00674803v1

Ahr-dependent lipid membrane remodelling: an early step facilitating benzo[a]pyrene-induced apoptosis

Jørn A. Holme , Xavier Tekpli , Béatrice Dendelé , Laure Debure , Odile Sergent et al.
49th annual meeting of Society of Toxicology and ToxExpo, Mar 2010, Salt Lake City, United States
Conference papers hal-00675239v1
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A new lactoferrin- and iron-dependent lysosomal death pathway is induced by benzo[a]pyrene in hepatic epithelial cells.

Morgane Gorria , Xavier Tekpli , Mary Rissel , Odile Sergent , Laurence Huc et al.
Toxicology and Applied Pharmacology, 2008, 228 (2), pp.212-24. ⟨10.1016/j.taap.2007.12.021⟩
Journal articles hal-00674390v1

Role for membrane remodeling in cell death: implication for health and disease.

Xavier Tekpli , Jørn A. Holme , Odile Sergent , Dominique Lagadic-Gossmann
Toxicology, 2013, 304, pp.141-57. ⟨10.1016/j.tox.2012.12.014⟩
Journal articles inserm-00818916v1

Importance of plasma membrane dynamics in chemical-induced carcinogenesis.

Xavier Tekpli , Jørn A. Holme , Odile Sergent , Dominique Lagadic-Gossmann
Recent Patents on Anti-Cancer Drug Discovery, 2011, 6 (3), pp.347-53. ⟨10.2174/157489211796957784⟩
Journal articles hal-00696148v1

The B[a]P-increased intercellular communication via translocation of connexin-43 into gap junctions reduces apoptosis.

Xavier Tekpli , Edgar Rivedal , Morgane Gorria , N. E. Landvik , Maryvonne Rissel et al.
Toxicology and Applied Pharmacology, 2010, 242 (2), pp.231-40. ⟨10.1016/j.taap.2009.10.012⟩
Journal articles istex hal-00660130v1

c-Jun NH2-terminal kinase-related Na+/H+ exchanger isoform 1 activation controls hexokinase II expression in benzo(a)pyrene-induced apoptosis.

Laurence Huc , Xavier Tekpli , Jørn A. Holme , Mary Rissel , Anita Solhaug et al.
Cancer Research, 2007, 67 (4), pp.1696-705. ⟨10.1158/0008-5472.CAN-06-2327⟩
Journal articles hal-00690320v1

Benzo[a]pyrene-induced apoptosis in hepatic epithelial F258 cells through regulation of mitochondrial hexokinase II expression by NHE1 activation

Laurence Huc , Xavier Tekpli , Jørn A. Holme , Maryvonne Rissel , Morgane Gorria et al.
Molecular Research in Environmental Medecine, Sep 2006, Paris, France
Conference papers hal-00699963v1
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NHE-1 relocation outside cholesterol-rich membrane microdomains is associated with its benzo[a]pyrene-related apoptotic function.

Xavier Tekpli , Laurence Huc , Odile Sergent , Béatrice Dendelé , Marie-Thérèse Dimanche-Boitrel et al.
Cellular Physiology and Biochemistry, 2012, 29 (5-6), pp.657-66. ⟨10.1159/000171027⟩
Journal articles inserm-00871487v1

Alternariol-induced ROS causes DNA damage and accumulation in the G2/M transition

Anita Solhaug , Jørn A. Holme , Laura L. Vines , Bjørn Spilsberg , Jim J. Pestka et al.
EUROTOX 2012, Jun 2012, Stockholm, Sweden. pp.S119, ⟨10.1016/j.toxlet.2012.03.439⟩
Conference papers istex hal-01122645v1
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Multiple apoptotic pathways induced by p53-dependent acidification in benzo[a]pyrene-exposed hepatic F258 cells.

Laurence Huc , Mary Rissel , Anita Solhaug , Xavier Tekpli , Morgane Gorria et al.
Journal of Cellular Physiology, 2006, 208 (3), pp.527-37. ⟨10.1002/jcp.20686⟩
Journal articles istex inserm-00130324v1

3-Nitrobenzanthrone and 3-aminobenzanthrone induce DNA damage and cell signalling in Hepa1c1c7 cells.

N. E. Landvik , V. M. Arlt , E. Nagy , Anita Solhaug , Xavier Tekpli et al.
Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis, 2010, 684 (1-2), pp.11-23. ⟨10.1016/j.mrfmmm.2009.11.004⟩
Journal articles istex hal-00696159v1

Mycotoxin-induced cell death and inflammatory responses in macrophages

Jørn A. Holme , Anders Gammelsrud , Beatrice Dendelé , Wiggo Sandberg , Dominique Lagadic-Gossmann et al.
EUROTOX 2012, Jun 2012, Stockholm, Sweden. pp.S133-S134, ⟨10.1016/j.toxlet.2012.03.489⟩
Conference papers istex hal-01122656v1