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authFullName_s : François Carreaux

[3,3]-Sigmatropic Rearrangement of Boronated Allylcyanates: A New Route to α-Aminoboronate Derivatives and Trisubstituted Tetrahydrofurans

Sabrina Touchet , Aurélie Macé , Thierry Roisnel , François Carreaux , Alexandre Bouillon et al.
Organic Letters, 2013, 15 (11), pp.2712-2715
Journal articles hal-02029934v1

Boron- and silicon-substituted [3]-1-heterodendralenes as versatile building blocks for the rapid construction of polycyclic architectures.

Fabien Tripoteau , Tristan Verdelet , Alain Hercouet , François Carreaux , Bertrand Carboni et al.
Chemistry - A European Journal, 2011, 17 (49), pp.13670-13675. ⟨10.1002/chem.201101624⟩
Journal articles istex hal-00869895v1

An efficient approach to dispacamide A and its derivatives.

Solène Guihéneuf , Ludovic Paquin , François Carreaux , Emilie Durieu , Laurent Meijer et al.
Organic & Biomolecular Chemistry, 2012, 10 (5), pp.978-87. ⟨10.1039/c1ob06161e⟩
Journal articles hal-00870469v1

[3,3]-Sigmatropic Rearrangement/Allylboration/Cyclization Sequence: Enantioenriched Seven-Membered-Ring Carbamates and Ring Contraction to Pyrrolidines

Aurélie Macé , Sabrina Touchet , Patricia Andres , Fernando Cossío , Vincent Dorcet et al.
Angewandte Chemie, 2016, 55 (3), pp.1025-1029 ⟨10.1002/anie.201509824⟩
Journal articles istex hal-01240655v1

cdc-like/dual-specificity tyrosine phosphorylation-regulated kinases inhibitor leucettine L41 induces mTOR-dependent autophagy: implication for Alzheimer's disease.

Xavier Fant , Emilie Durieu , Gaëtan Chicanne , Bernard Payrastre , Diego Sbrissa et al.
Molecular Pharmacology, 2014, 85 (3), pp.441-50. ⟨10.1124/mol.113.090837⟩
Journal articles inserm-01012086v1

Leucettines, a class of potent inhibitors of cdc2-like kinases and dual specificity, tyrosine phosphorylation regulated kinases derived from the marine sponge leucettamine B: modulation of alternative pre-RNA splicing.

Mansour Debdab , François Carreaux , Steven Renault , Meera Soundararajan , Oleg Fedorov et al.
Journal of Medicinal Chemistry, 2011, 54 (12), pp.4172-86. ⟨10.1021/jm200274d⟩
Journal articles hal-00870007v1
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Leucettine L41, a DYRK1A-preferential DYRKs/CLKs inhibitor, prevents memory impairments and neurotoxicity induced by oligomeric Aβ25-35 peptide administration in mice.

Gaëlle Naert , Valentine Ferré , Johann Meunier , Emeline Keller , Susanna Malmstrom et al.
European Neuropsychopharmacology, 2015, 25 (11), pp.2170-2182. ⟨10.1016/j.euroneuro.2015.03.018⟩
Journal articles hal-01146496v1

Alkenylboron Cross-Coupling

Bertrand Carboni , François Carreaux
Mats Larhed, John P. Wolfe, G. Molander. Science of Synthesis, Georg Thieme Verlag, pp.265-322, 2012
Book sections hal-00873122v1
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Marine-Derived 2-Aminoimidazolone Alkaloids. Leucettamine B-Related Polyandrocarpamines Inhibit Mammalian and Protozoan DYRK & CLK Kinases

Nadège Loaëc , Eletta Attanasio , Benoît Villiers , Emilie Durieu , Tania Tahtouh et al.
Marine drugs, 2017, 15 (10), pp.316 -. ⟨10.3390/md15100316⟩
Journal articles hal-01640115v1
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Microwave-Assisted 1,3-Dioxa-[3,3]-Sigmatropic Rearrangement of Substituted Allylic Carbamates: Application to the Synthesis of Novel 1,3-Oxazine-2,4-dione Derivatives

Samar Bou Zeid , Samar Eid , Fadia Najjar , Aurélie Macé , Ivan Rivilla et al.
European Journal of Organic Chemistry, 2022, 2022 (1), ⟨10.1002/ejoc.202101100⟩
Journal articles hal-03464791v1

Structural and molecular bases to IRE1 activity modulation

Timothy Langlais , Diana Pelizzari-Raymundo , Sayyed Jalil Mahdizadeh , Nicolas Gouault , François Carreaux et al.
Biochemical Journal, 2021, 478 (15), pp.2953-2975. ⟨10.1042/BCJ20200919⟩
Journal articles hal-03331317v1

Structure-Activity Relationship in the Leucettine Family of Kinase Inhibitors

Tania Tahtouh , Emilie Durieu , Benoit Villiers , Celine Bruyere , Thu Lan Nguyen et al.
Journal of Medicinal Chemistry, 2022, 65 (2), pp.1396-1417. ⟨10.1021/acs.jmedchem.1c01141⟩
Journal articles hal-03512536v1
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BINOL derivatives-catalysed enantioselective allylboration of isatins: application to the synthesis of (R)-chimonamidine

Julien Braire , Vincent Dorcet , Joëlle Vidal , Claudia Lalli , François Carreaux et al.
Organic & Biomolecular Chemistry, 2020, 18 (31), pp.6042-6046. ⟨10.1039/d0ob01386b⟩
Journal articles hal-02928635v1

Synthesis of alkenyl boronates from allyl-substituted aromatics using an olefin cross-metathesis protocol.

Rémy Hemelaere , François Carreaux , Bertrand Carboni
Journal of Organic Chemistry, 2013, 78 (13), pp.6786-92. ⟨10.1021/jo400872x⟩
Journal articles hal-00861076v1

A Diastereoselective Route to trans-​2-​Aryl-​2,​3-​dihydrobenzofurans through Sequential Cross-​Metathesis​/Isomerization​/Allylboration Reactions: Synthesis of Bioactive Neolignans

Rémy Hemelaere , François Carreaux , Bertrand Carboni
European Journal of Organic Chemistry, 2015, 2015 (11), pp.2470-2481. ⟨10.1002/ejoc.201500019⟩
Journal articles istex hal-01138641v1

Pentamethylcyclopentadienyl ruthenium: an efficient catalyst for the redox isomerization of functionalized allylic alcohols into carbonyl compounds

Asmae Bouziane , Bertrand Carboni , Christian Bruneau , François Carreaux , Jean-Luc Renaud et al.
Tetrahedron, 2008, 64, pp.11745-11750
Journal articles hal-00356814v1

Solid-phase reactions of resin-supported boronic acids

François Carreaux , Bertrand Carboni , Hervé Deleuze , Christelle Pourbaix-L'Ebraly
Peter J. H. Scott. Solid-Phase Organic Syntheses, Wiley, pp.107-118, 2012, ⟨10.1002/9781118336953.ch12⟩
Book sections hal-00873126v1
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A Practical Approach to New (5Z) 2-Alkylthio-5-arylmethylene- 1-methyl-1,5-dihydro-4H-imidazol-4-one Derivatives

Khadidja Bourahla , Ludovic Paquin , Olivier Lozach , Laurent Meijer , François Carreaux et al.
Molecules, 2011, 16, pp.7377-7390. ⟨10.3390/molecules16097377⟩
Journal articles hal-00870301v1

Iridium-Catalyzed Allylic Amination Route to α-Aminoboronates: Illustration of the Decisive Role of Boron Substituents.

Sabrina Touchet , François Carreaux , Gary A. Molander , Bertrand Carboni , Alexandre Bouillon et al.
Advanced Synthesis and Catalysis, 2011, 353 (18), pp.3391-3396. ⟨10.1002/adsc.201100407⟩
Journal articles hal-00869890v1

A Practical Access to Novel 2-Amino-5-arylidene-thiazol-4-ones via Sulfur/nitrogen Displacement under Solvent-free Microwave Irradiations.

Khadidja Bourahlaa , Aicha Derdour , Mustapha Rahmouni , François Carreaux , J.P. Bazureau et al.
Tetrahedron Letters, 2007, pp.5785-5789
Journal articles hal-00410745v1
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Synthetic alkyl-ether-lipid promotes TRPV2 channel trafficking trough PI3K/Akt-girdin axis in cancer cells and increases mammary tumour volume

Maxime Guéguinou , Romain Felix , Séverine Marionneau-Lambot , Thibauld Oullier , Aubin Penna et al.
Cell Calcium, 2021, 97, pp.102435. ⟨10.1016/j.ceca.2021.102435⟩
Journal articles hal-03278876v1

Ruthenium-Catalyzed Synthesis of Allylic Alcohols: Boronic Acid as a Hydroxide Source

Asmae Bouziane , Marion Helou , Bertrand Carboni , François Carreaux , Bernard Demerseman et al.
Chemistry, Eur., 2008, pp.5630-5637
Journal articles hal-00356801v1

Synthesis and preliminary biological evaluation of new derivatives of the marine alkaloid leucettamine B as kinase inhibitors.

Mansour Debdab , Stéven Renault , Olivier Lozach , Laurent Meijer , Ludovic Paquin et al.
European Journal of Medicinal Chemistry, 2010, 45 (2), pp.805-10. ⟨10.1016/j.ejmech.2009.10.009⟩
Journal articles istex hal-00869769v1

Aminoboronic acids and esters: from synthetic challenges to the discovery of unique classes of enzyme inhibitors.

Sabrina Touchet , François Carreaux , Bertrand Carboni , Alexandre Bouillon , Jean-Luc Boucher et al.
Chemical Society Reviews, 2011, 40 (7), pp.3895-914. ⟨10.1039/c0cs00154f⟩
Journal articles hal-00869909v1

Dérivés d'imidazolones, procédé de préparation et applications biologiques.

J.P. Bazureau , François Carreaux , Stéven Renault , Laurent Meijer , Olivier Lozach et al.
Patent n° : FR 291 9608 (A1). 2009
Patents hal-00411458v1

Selectivity, cocrystal structures, and neuroprotective properties of leucettines, a family of protein kinase inhibitors derived from the marine sponge alkaloid leucettamine B.

Tania Tahtouh , Jonathan M. Elkins , Panagis Filippakopoulos , Meera Soundararajan , Guillaume Burgy et al.
Journal of Medicinal Chemistry, 2012, 55 (21), pp.9312-30. ⟨10.1021/jm301034u⟩
Journal articles hal-00870472v1

(E)-Α-Substituted Γ-Alkoxyallylboronic Esters as New Reagents: Synthesis and Reactivity toward Aldehydes.

Françoise Possémé , Michael Deligny , François Carreaux , Bertrand Carboni
Journal of Organic Chemistry, 2008, 72, pp.984-989
Journal articles hal-00356454v1

An expeditious, environment-friendly, and microwave-assisted synthesis of 5-isatinylidenerhodanine derivatives

Abdelmounaim Safer , Mustapha Rahmouni , François Carreaux , Ludovic Paquin , Olivier Lozach et al.
Chemical Papers, 2011, 65 (3), pp.332-337. ⟨10.2478/s11696-010-0104-9⟩
Journal articles hal-00869920v1

Iridium-Catalyzed Allylic Amination Route to α-Aminoboronates: Illustration of the Decisive Role of Boron Substituents

Sabrina Touchet , François Carreaux , Gary Molander , Bertrand Carboni , Alexandre Bouillon et al.
Advanced Synthesis and Catalysis, 2011, 353 (18), pp.3391-3396
Journal articles hal-02029761v1
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Inhibition of DYRK1A proteolysis modifies its kinase specificity and rescues Alzheimer phenotype in APP/PS1 mice

Benoit Souchet , Mickael Audrain , Jean Marie Billard , Julien Dairou , Romain Fol et al.
Acta Neuropathologica Communications, 2019, 7 (1), pp.46. ⟨10.1186/s40478-019-0678-6⟩
Journal articles hal-02324924v1