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authFullName_s : Dounia Le Guillou
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A cellular model to study drug-induced liver injury in nonalcoholic fatty liver disease: application to acetaminophen

Anaïs Michaut , Dounia Le Guillou , Caroline Moreau , Simon Bucher , Mitchell R. Mcgill et al.
Toxicology and Applied Pharmacology, 2016, 292, pp.40-55. ⟨10.1016/j.taap.2015.12.020⟩
Journal articles hal-01255826v1
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Co-exposure to benzo[a]pyrene and ethanol induces a pathological progression of liver steatosis in vitro and in vivo

Simon Bucher , Arnaud Tête , Normand Podechard , Marie Liamin , Dounia Le Guillou et al.
Scientific Reports, 2018, 8 (1), pp.5963. ⟨10.1038/s41598-018-24403-1⟩
Journal articles hal-01771620v1
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Bisphenol A induces steatosis in HepaRG cells using a model of perinatal exposure

Simon Bucher , Pégah Jalili , Dounia Le Guillou , Karima Begriche , Karine Rondel et al.
Environmental Toxicology, 2017, 32 (3), pp.1024-1036. ⟨10.1002/tox.22301⟩
Journal articles hal-01470709v1
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Drug-induced hepatic steatosis in absence of severe mitochondrial dysfunction in HepaRG cells: proof of multiple mechanism-based toxicity

Julien Allard , Simon Bucher , Julie Massart , Pierre-Jean Ferron , Dounia Le Guillou et al.
Cell Biology and Toxicology, 2021, 37 (2), pp.151-175. ⟨10.1007/s10565-020-09537-1⟩
Journal articles hal-02886702v1

Endotoxin regulates matrix genes increasing reactive oxygen species generation by intercellular communication between palmitate-treated hepatocyte and stellate cell

Waleska Dornas , Denise Glaise , Aude Bodin , Ahmad Sharanek , Audrey Burban et al.
Journal of Cellular Physiology, 2019, 234 (1), pp.122-133. ⟨10.1002/jcp.27175⟩
Journal articles hal-01880153v1
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Possible Involvement of Mitochondrial Dysfunction and Oxidative Stress in a Cellular Model of NAFLD Progression Induced by Benzo[a]pyrene/Ethanol CoExposure

Simon Bucher , Dounia Le Guillou , Julien Allard , Gregory Pinon , Karima Begriche et al.
Oxidative Medicine and Cellular Longevity, 2018, 2018, pp.4396403. ⟨10.1155/2018/4396403⟩
Journal articles hal-01861586v1
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Chronic exposure to low doses of pharmaceuticals disturbs the hepatic expression of circadian genes in lean and obese mice.

Sébastien Anthérieu , Dounia Le Guillou , Cédric Coulouarn , Karima Begriche , Viviane Trak-Smayra et al.
Toxicology and Applied Pharmacology, 2014, 276 (1), pp.63-72. ⟨10.1016/j.taap.2014.01.019⟩
Journal articles hal-01057872v1
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Drug-Induced Alterations of Mitochondrial DNA Homeostasis in Steatotic and Nonsteatotic HepaRG Cells

Dounia Le Guillou , Simon Bucher , Karima Begriche , Delphine Hoët , Anne Lombès et al.
Journal of Pharmacology and Experimental Therapeutics, 2018, 365 (3), pp.711-726. ⟨10.1124/jpet.117.246751⟩
Journal articles hal-01808097v1