Tacrine inhibits topoisomerases and DNA synthesis to cause mitochondrial DNA depletion and apoptosis in mouse liver
Abdellah Mansouri
,
Delphine Haouzi
,
Véronique Descatoire
,
Christine Demeilliers
,
Angela Sutton
et al.
Journal articles
hal-02185531v1
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Drug-induced liver injury in obesity
Bernard Fromenty
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hal-00865967v1
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Fat accretion in a subpopulation of hepatocytes as a strategy to protect the whole liver against oxidative stress and lipotoxicity.
Bernard Fromenty
Gastroentérologie Clinique et Biologique / Research and Clinics in Hepatology and Gastroenterology , 2013, 37 (6), pp.553-555.
⟨10.1016/j.clinre.2013.08.005⟩
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inserm-00869996v1
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Mitochondrial alterations in fatty liver diseases
Bernard Fromenty
,
Michael Roden
Journal articles
hal-03829001v1
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L’analyse du sérum par spectroscopie moyen infrarouge permet d’obtenir une signature du statut métabolique du foie chez la souris
Maëna Le Corvec
,
Coralie Allain
,
Salim Lardjane
,
Thibault Cavey
,
Bruno Turlin
et al.
Journal articles
hal-01501832v1
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Letter to the Editor Regarding the Article: Rotenone Increases Isoniazid Toxicity but Does Not Cause Significant Liver Injury Implications for the Hypothesis that Inhibition of the Mitochondrial Electron Transport Chain Is a Common Mechanism of Idiosyncratic Drug-Induced Liver Injury by Cho and Co-Workers, 2019
Bernard Fromenty
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hal-02442529v1
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Mechanisms involved in the death of steatotic WIF-B9 hepatocytes co-exposed to benzo[a]pyrene and ethanol a possible key role for xenobiotic metabolism and nitric oxide
Arnaud Tête
,
Isabelle Gallais
,
Muhammad Imran
,
Martine Chevanne
,
Marie Liamin
et al.
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hal-01888877v1
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A cellular model to study drug-induced liver injury in nonalcoholic fatty liver disease: application to acetaminophen
Anaïs Michaut
,
Dounia Le Guillou
,
Caroline Moreau
,
Simon Bucher
,
Mitchell R. Mcgill
et al.
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hal-01255826v1
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Modulation of metabolizing enzymes by bisphenol a in human and animal models.
Nicolas Quesnot
,
Simon Bucher
,
Bernard Fromenty
,
Marie-Anne Robin
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hal-01134758v1
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Prediction of Liver Injury Induced by Chemicals in Human with a Multiparametric Assay on Isolated Mouse Liver Mitochondria.
Mathieu Porceddu
,
Nelly Buron
,
Célestin Roussel
,
Gilles Labbe
,
Bernard Fromenty
et al.
Journal articles
hal-00866136v1
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Increased susceptibility to liver fibrosis with age is correlated with an altered inflammatory response.
Meriem Mahrouf-Yorgov
,
Alexandra Collin de L'Hortet
,
Claudine Cosson
,
Abdelhamid Slama
,
Elsa Abdoun
et al.
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hal-00740103v1
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Mid-infrared fibre evanescent wave spectroscopy of serum allows fingerprinting of the hepatic metabolic status in mice
Maëna Le Corvec
,
Coralie Allain
,
Salim Lardjane
,
Thibault Cavey
,
Bruno Turlin
et al.
Journal articles
hal-01450518v1
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Chronic and low exposure to a pharmaceutical cocktail induces mitochondrial dysfunction in liver and hyperglycemia: Differential responses between lean and obese mice
Nelly Buron
,
Mathieu Porceddu
,
Célestin Roussel
,
Karima Begriche
,
Viviane Trak-Smayra
et al.
Journal articles
hal-01502386v1
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Worsening of obesity-related non-alcoholic liver diseases by xenobiotics
Bernard Fromenty
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hal-01058635v1
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Acetaminophen-induced liver injury in obesity and nonalcoholic fatty liver disease
Anaïs Michaut
,
Caroline Moreau
,
Marie-Anne Robin
,
Bernard Fromenty
Journal articles
hal-01128195v1
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Co-exposure to benzo[a]pyrene and ethanol induces a pathological progression of liver steatosis in vitro and in vivo
Simon Bucher
,
Arnaud Tête
,
Normand Podechard
,
Marie Liamin
,
Dounia Le Guillou
et al.
Journal articles
hal-01771620v1
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Retrodifferentiation of human tumor hepatocytes to stem cells leads to metabolic reprogramming and chemoresistance
Karim Fekir
,
Hélène Dubois-Pot-Schneider
,
Romain Desert
,
Yoann Daniel
,
Denise Glaise
et al.
Journal articles
hal-02087900v1
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Moderate chronic ethanol consumption exerts beneficial effects on nonalcoholic fatty liver in mice fed a high-fat diet possible role of higher formation of triglycerides enriched in monounsaturated fatty acids
Simon Bucher
,
Karima Begriche
,
Daniel D. Catheline
,
Viviane Trak-Smayra
,
François Tiaho
et al.
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hal-02152865v1
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Gamma-glutamyltransferase, fatty liver index and hepatic insulin resistance are associated with incident hypertension in two longitudinal studies
Fabrice Bonnet
,
Amalia Gastaldelli
,
Florence Pihan-Le Bars
,
Andrea Natali
,
Ronan Roussel
et al.
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hal-01447061v1
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Pentoxifylline aggravates fatty liver in obese and diabetic ob/ob mice by increasing intestinal glucose absorption and activating hepatic lipogenesis.
Julie Massart
,
Marie-Anne Robin
,
Fanny Noury
,
Alain Fautrel
,
P. Lettéron
et al.
Journal articles
hal-00740120v1
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The effect of water suppression on the hepatic lipid quantification, as assessed by the LCModel, in a preclinical and clinical scenario
Amandine Coum
,
Fanny Noury
,
Elise Bannier
,
Karima Begriche
,
Bernard Fromenty
et al.
Journal articles
hal-01237087v1
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Fatal acetaminophen poisoning with hepatic microvesicular steatosis in a child after repeated administration of therapeutic doses
Renaud Bouvet
,
Aurelie Cauchois
,
Alain Baert
,
Bernard Fromenty
,
Isabelle Morel
et al.
Journal articles
hal-02563468v1
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Transcriptomic analysis in zebrafish larvae identifies iron-dependent mitochondrial dysfunction as a possible key event of NAFLD progression induced by benzo[a]pyrene/ethanol co-exposure
Muhammad Imran
,
Frédéric Chalmel
,
Odile Sergent
,
Bertrand Evrard
,
Hélène Le Mentec
et al.
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hal-03647402v1
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Role of Mitochondrial Cytochrome P450 2E1 in Healthy and Diseased Liver
Julie Massart
,
Karima Begriche
,
Jessica H Hartman
,
Bernard Fromenty
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hal-03555433v1
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Beneficial effects of citrulline enteral administration on sepsis-induced T cell mitochondrial dysfunction
Florian Reizine
,
Murielle Grégoire
,
Mathieu Lesouhaitier
,
Valentin Coirier
,
Juliette Gauthier
et al.
Proceedings of the National Academy of Sciences of the United States of America , 2022, 119 (8), pp.e2115139119.
⟨10.1073/pnas.2115139119⟩
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hal-03594344v1
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Multikinase inhibitor-induced liver injury in patients with cancer: A review for clinicians
Camille Houron
,
Marie Danielou
,
Olivier Mir
,
Bernard Fromenty
,
Gabriel Perlemuter
et al.
Journal articles
hal-03001637v1
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MnSOD overexpression prevents liver mitochondrial DNA depletion after an alcohol binge but worsens this effect after prolonged alcohol consumption in mice.
Abdellah Mansouri
,
Arige Tarhuni
,
Isabelle Larosche
,
Florence Reyl-Desmars
,
C. Demeilliers
et al.
Journal articles
hal-00866337v1
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Cocktail de pesticides et stéatose hépatique
Bernard Fromenty
Les cahiers de la Recherche. Santé, Environnement, Travail , 2021, Les contaminants chimiques seuls ou en mélange, 16, pp.44-45
Journal articles
anses-03211753v1
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Acetaminophen (APAP, paracetamol) interferes with the first trimester human fetal ovary development in an ex vivo model
Laetitia L Lecante
,
Sabrina Leverrier-Penna
,
Thomas Gicquel
,
Frank Giton
,
Nathalie Costet
et al.
Journal articles
hal-03578173v1
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Regulation of hepatic mitochondrial metabolism in response to a high fat diet: a longitudinal study in rats.
Mélissa Flamment
,
Jennifer Rieusset
,
Hubert Vidal
,
Gilles Simard
,
Yves Malthièry
et al.
Journal articles
hal-00866142v1
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