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authFullName_s : Arnaud Bruyère

Interactions of janus kinase inhibitors with drug transporters and consequences for pharmacokinetics and toxicity

Karima Alim , Arnaud Bruyère , Alain Lescoat , Elodie Jouan , Valérie Lecureur et al.
Expert Opinion on Drug Metabolism and Toxicology, 2021, 17 (3), pp.259-271. ⟨10.1080/17425255.2021.1862084⟩
Journal articles hal-03095585v1
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Drivers of absolute systemic bioavailability after oral pulmonary inhalation in humans

Astrid Bacle , Guillaume Bouzillé , Arnaud Bruyère , Marc Cuggia , Olivier Fardel et al.
European Journal of Pharmaceutics and Biopharmaceutics, 2021, 164, pp.36-53. ⟨10.1016/j.ejpb.2021.04.014⟩
Journal articles hal-03222648v1
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In vitro long term differentiation and functionality of three-dimensional bioprinted primary human hepatocytes: application for in vivo engraftment

Marie Cuvellier , Sophie Rose , Frédéric Ezan , Ulrich Jarry , Hugo de Oliveira et al.
Biofabrication, 2022, 14 (3), pp.035021. ⟨10.1088/1758-5090/ac7825⟩
Journal articles hal-03710469v1

Implication of human drug transporters to toxicokinetics and toxicity of pesticides

Nelly Gueniche , Arnaud Bruyère , Marc Le Vée , Olivier Fardel
Pest Management Science, 2020, 76 (1), pp.18-25. ⟨10.1002/ps.5577⟩
Journal articles anses-02366326v1

Protein Kinase C-Independent Inhibition of Organic Cation Transporter 1 Activity by the Bisindolylmaleimide Ro 31-8220

Abdullah Mayati , Arnaud Bruyère , Amélie Moreau , Elodie Jouan , Claire Denizot et al.
PLoS ONE, 2015, 10 (12), pp.e0144667. ⟨10.1371/journal.pone.0144667⟩
Journal articles hal-01255837v1
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Functional polarization of human hepatoma HepaRG cells in response to forskolin

Abdullah Mayati , Amelie Moreau , Marc Le Vée , Arnaud Bruyère , Elodie Jouan et al.
Scientific Reports, 2018, 8 (1), pp.16115. ⟨10.1038/s41598-018-34421-8⟩
Journal articles hal-01973693v1
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Interactions of organophosphorus pesticides with solute carrier (SLC) drug transporters

Lisa Chedik , Arnaud Bruyère , Olivier Fardel
Xenobiotica, 2019, 49 (3), pp.363-374. ⟨10.1080/00498254.2018.1442030⟩
Journal articles hal-01863798v1
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Differential interactions of carbamate pesticides with drug transporters

Nelly Gueniche , Arnaud Bruyère , Mélanie Ringeval , Elodie Jouan , Antoine Huguet et al.
Xenobiotica, 2020, 50 (11), pp.1380-1392. ⟨10.1080/00498254.2020.1771473⟩
Journal articles anses-02626126v1
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PBPK model of methotrexate in cerebrospinal fluid ventricles using a combined microdialysis and MRI acquisition

Nolwenn Brandhonneur , Fanny Noury , Arnaud Bruyère , Hervé Saint-Jalmes , Pascal Le Corre et al.
European Journal of Pharmaceutics and Biopharmaceutics, 2016, 104, pp.117-130. ⟨10.1016/j.ejpb.2016.04.012⟩
Journal articles hal-01335562v1
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Differential in vitro interactions of the Janus kinase inhibitor ruxolitinib with human SLC drug transporters

Arnaud Bruyère , Marc Le Vée , Elodie Jouan , Stephanie Molez , Anne T Nies et al.
Xenobiotica, 2021, 51 (4), pp.467-478. ⟨10.1080/00498254.2021.1875516⟩
Journal articles hal-03134537v1
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Inhibition of Human Drug Transporter Activities by the Pyrethroid Pesticides Allethrin and Tetramethrin.

Lisa Chedik , Arnaud Bruyère , Marc Le Vee , Bruno Stieger , Claire Denizot et al.
PLoS ONE, 2017, 12 (1), pp.e0169480. ⟨10.1371/journal.pone.0169480⟩
Journal articles hal-01477206v1
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The JAK1/2 Inhibitor Ruxolitinib Reverses Interleukin-6-Mediated Suppression of Drug-Detoxifying Proteins in Cultured Human Hepatocytes

Marie Febvre-James , Arnaud Bruyère , Marc Le Vée , Olivier Fardel
Drug Metabolism and Disposition, 2018, 46 (2), pp.131-140. ⟨10.1124/dmd.117.078048⟩
Journal articles hal-01699218v1
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Generation of proliferating human adult hepatocytes using optimized 3D culture conditions

Sophie Rose , Frédéric Ezan , Marie Cuvellier , Arnaud Bruyère , Vincent Legagneux et al.
Scientific Reports, 2021, 11 (1), pp.515. ⟨10.1038/s41598-020-80019-4⟩
Journal articles hal-03134402v1
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Inhibition of organic cation transporter 3 activity by tyrosine kinase inhibitors

Karima Alim , Amélie Moreau , Arnaud Bruyère , Elodie Jouan , Claire Denizot et al.
Fundamental & Clinical Pharmacology, 2021, ⟨10.1111/fcp.12657⟩
Journal articles hal-03134613v1

Interactions of organophosphorus pesticides with ATP-Binding Cassette (ABC) drug transporters

Lisa Chedik , Dominique Mias-Lucquin , Olivier Fardel , Olivier Delalande , Arnaud Bruyère et al.
Xenobiotica, 2022, 52 (6), pp.644-652. ⟨10.1080/00498254.2022.2128467⟩
Journal articles hal-03790186v1
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Inhibition of organic cation transporter (OCT) activities by carcinogenic heterocyclic aromatic amines

Katia Sayyed , Christophe Camillerapp , Marc Le Vée , Arnaud Bruyère , Anne T Nies et al.
Toxicology in Vitro, 2019, 54, pp.10-22. ⟨10.1016/j.tiv.2018.08.015⟩
Journal articles hal-01903262v1

Neonicotinoid pesticides poorly interact with human drug transporters

Marc Le Vée , Astrid Bacle , Arnaud Bruyère , Olivier Fardel
Journal of Biochemical and Molecular Toxicology, 2019, 33 (10), pp.e22379. ⟨10.1002/jbt.22379⟩
Journal articles hal-02278081v1

In Silico Prediction for Intestinal Absorption and Brain Penetration of Chemical Pesticides in Humans

Lisa Chedik , Dominique Mias-Lucquin , Arnaud Bruyère , Olivier Fardel
International Journal of Environmental Research and Public Health, 2017, 14 (7), pp.708. ⟨10.3390/ijerph14070708⟩
Journal articles hal-01560242v1

Interactions of endosulfan and methoxychlor involving CYP3A4 and CYP2B6 in human HepaRG cells.

Camille C Savary , Rozenn Jossé , Arnaud Bruyère , Fabrice Guillet , Marie-Anne Robin et al.
Drug Metabolism and Disposition, 2014, 42 (8), pp.1235-40. ⟨10.1124/dmd.114.057786⟩
Journal articles hal-01128192v1
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Interactions of pesticides with membrane drug transporters implications for toxicokinetics and toxicity

Lisa Chedik , Arnaud Bruyère , Astrid Bacle , Sophie Potin , Marc Le Vée et al.
Expert Opinion on Drug Metabolism and Toxicology, 2018, 14 (7), pp.739-752. ⟨10.1080/17425255.2018.1487398⟩
Journal articles hal-01863032v2