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authFullName_s : Afshin Samali
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Control of anterior GRadient 2 (AGR2) dimerization links endoplasmic reticulum proteostasis to inflammation

Marion Maurel , Joanna Obacz , Tony Avril , Yong-Ping Ding , Olga Papadodima et al.
EMBO Molecular Medicine, 2019, 11 (6), pp.e10120. ⟨10.15252/emmm.201810120⟩
Journal articles hal-02160377v1

Drugging the unfolded protein response in acute leukemias

Behzad Kharabi Masouleh , Eric Chevet , Jens Panse , Edgar Jost , Michael O'Dwyer et al.
Journal of Hematology and Oncology, 2015, 8 (1), pp.87. ⟨10.1186/s13045-015-0184-7⟩
Journal articles hal-01187303v1
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Inhibition of IRE1 RNase activity modulates the tumor cell secretome and enhances response to chemotherapy

Susan E. Logue , Eoghan P. Mcgrath , Patricia Cleary , Stephanie Greene , Katarzyna Mnich et al.
Nature Communications, 2018, 9 (1), pp.3267. ⟨10.1038/s41467-018-05763-8⟩
Journal articles hal-01879955v1
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The unfolded protein response modulators GSK2606414 and KIRA6 are potent KIT inhibitors

Mohamed Mahameed , Thomas Wilhelm , Odai Darawshi , Akram Obiedat , Weiss-Sadan Tommy et al.
Cell Death and Disease, 2019, 10 (4), pp.300. ⟨10.1038/s41419-019-1523-3⟩
Journal articles hal-02121105v1
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Peptidomimetic-based identification of FDA approved compounds inhibiting IRE1 activity

Dimitrios Doultsinos , Antonio Carlesso , Chetan Chintha , James C Paton , Adrienne W Paton et al.
FEBS Journal, 2021, 288 (3), pp.945-960. ⟨10.1111/febs.15372⟩
Journal articles hal-02862262v1
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Novel roles of the Unfolded Protein Response in the control of tumor development and aggressiveness

Nicolas Dejeans , Kim Barroso , Martin E. Fernandez-Zapico , Afshin Samali , Eric Chevet et al.
Seminars in Cancer Biology, 2015, 33, pp.67-73. ⟨10.1016/j.semcancer.2015.04.007⟩
Journal articles hal-01150385v1
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Dual IRE1 RNase functions dictate glioblastoma development

Stéphanie Lhomond , Tony Avril , Nicolas Dejeans , Konstantinos Voutetakis , Dimitrios Doultsinos et al.
EMBO Molecular Medicine, 2018, 10 (3), pp.e7929. ⟨10.15252/emmm.201707929⟩
Journal articles hal-01777737v1
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Regulated IRE1 alpha-dependent decay (RIDD)-mediated reprograming of lipid metabolism in cancer

Aitor Almanza , Katarzyna Mnich , Arnaud Blomme , Claire M. Robinson , Giovanny Rodriguez-Blanco et al.
Nature Communications, 2022, 13 (1), pp.2493. ⟨10.1038/s41467-022-30159-0⟩
Journal articles hal-03689648v1
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Endoplasmic reticulum stress signalling - from basic mechanisms to clinical applications

Aitor Almanza , Antonio Carlesso , Chetan Chintha , Stuart Creedican , Dimitrios Doultsinos et al.
FEBS Journal, 2019, 286 (2), pp.241-278. ⟨10.1111/febs.14608⟩
Journal articles hal-01940307v1
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Regulation of the unfolded protein response by noncoding RNA

Mari Mcmahon , Afshin Samali , Eric Chevet
American Journal of Physiology - Cell Physiology, 2017, 313 (3), pp.C243-C254. ⟨10.1152/ajpcell.00293.2016⟩
Journal articles hal-01586174v1

Controlling the unfolded protein response-mediated life and death decisions in cancer

Marion Maurel , Eoghan P. Mcgrath , Katarzyna Mnich , Sandra Healy , Eric Chevet et al.
Seminars in Cancer Biology, 2015, 33, pp.57-66. ⟨10.1016/j.semcancer.2015.03.003⟩
Journal articles hal-01163729v1
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Local intracerebral inhibition of IRE1 by MKC8866 sensitizes glioblastoma to irradiation/chemotherapy in vivo

Pierre Jean Le Reste , R Pineau , Konstantinos Voutetakis , J Samal , Gwenaele Jegou et al.
Cancer Letters, 2020, 494, pp.73-83. ⟨10.1016/j.canlet.2020.08.028⟩
Journal articles hal-02959985v1

Deregulated expression of the HSP40 family members Auxilin-1 and -2 is indicative of proteostasis imbalance and predicts patient outcome in Ph+ leukemia

Margherita Vieri , Huimin Geng , John B. Patterson , Jens Panse , Stefan Wilop et al.
Experimental Hematology & Oncology, 2016, 5 (1), pp.5. ⟨10.1186/s40164-016-0034-5⟩
Journal articles hal-01274235v1
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Endoplasmic Reticulum Stress-Activated Cell Reprogramming in Oncogenesis

Eric Chevet , Claudio Hetz , Afshin Samali
Cancer Discovery, 2015, 5 (6), pp.586-97. ⟨10.1158/2159-8290.CD-14-1490⟩
Journal articles hal-01152845v1

Maintenance of Endoplasmic Reticulum Protein Homeostasis in Cancer: Friend or Foe

Mari Mcmahon , Afshin Samali , Eric Chevet
Progress in Molecular and Subcellular Biology, 59, Springer Verlag, Heidelberg, Germany, pp.197-214, 2021, ⟨10.1007/978-3-030-67696-4_10⟩
Book sections hal-03248171v1