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Article Dans Une Revue British Journal of Haematology Année : 2019

Survival and specific outcome of sickle cell disease patients after renal transplantation

Christel Gérardin
  • Fonction : Auteur
Philippe Gataut
  • Fonction : Auteur
Marine Novion
  • Fonction : Auteur
Marie‐julia Ziliotis
  • Fonction : Auteur
Magali Louis
  • Fonction : Auteur
Karine Dahan
  • Fonction : Auteur

Résumé

The prognosis of sickle cell disease (SCD) patients who need dialysis is poor, but experience with kidney transplantation is limited. This study assessed the characteristics of 36 SCD patients undergoing renal transplantation. Immediate post-surgical complications occurred in 25% of cases. Cytomegalovirus and bacterial infections were frequently observed. Twelve patients died after a median follow-up period of17-4 months. Overall patient survival was significantly lower in SCD than in the control group without significant difference for overall death-censored graft sur-vival. Our data suggest that renal transplantation should be systematically considered in SCD patients with end-stage renal disease.

Dates et versions

inserm-02285824 , version 1 (13-09-2019)

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Citer

Christel Gérardin, Anissa Moktefi, Cécile Couchoud, Alyette Duquesne, Nacera Ouali, et al.. Survival and specific outcome of sickle cell disease patients after renal transplantation. British Journal of Haematology, 2019, ⟨10.1111/bjh.16113⟩. ⟨inserm-02285824⟩
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