Description des caractéristiques, des projets de soins et du devenir des patients de plus 75 ans présentant une insuffisance rénale sévère (DFGe ≤ 20 mL/min/1,73 m2) : phase pilote du projet PSPA [Description of characteristics, therapeutic project and outcome of patients older than 75 years with eGFR below 20mL/min/1.73m(2): PSPA pilot study.] - Université de Rennes Accéder directement au contenu
Article Dans Une Revue Néphrologie & Thérapeutique Année : 2012

Description des caractéristiques, des projets de soins et du devenir des patients de plus 75 ans présentant une insuffisance rénale sévère (DFGe ≤ 20 mL/min/1,73 m2) : phase pilote du projet PSPA [Description of characteristics, therapeutic project and outcome of patients older than 75 years with eGFR below 20mL/min/1.73m(2): PSPA pilot study.]

Résumé

In France, the incidence of dialysis patients is increasing in people over 75 years and represents 40% of incident patients. In these elderly patients with many comorbidities, the benefit of dialysis in terms of survival and quality of life remains controversial. Using data from REIN, determinants of early mortality were identified and a prognostic score was provided. This approach must now be adapted to elderly with end stage renal failure (ESRF) not on dialysis for which we have little data on their clinical characteristics, therapeutic projects and outcome. We report the results of a pilot study and the prospective study protocol that resulted. In four French nephrology department, 76 patients were studied with a mean age of 83±5 years, with a MDRD estimated GFR (abbreviated MDRD) of 16±4mL/min/1.73m(2). These patients were different from the population on dialysis recorded in REIN. This pilot study has shown the feasibility of a prospective study on a larger scale, which aims to build a valuable tool for decision making in elderly patients with ESRF not yet on dialysis.

Dates et versions

inserm-00696101 , version 1 (10-05-2012)

Identifiants

Citer

Olivier Moranne, Cécile Couchoud, Anne Kolko-Labadens, Vincent Allot, Coraline Fafin, et al.. Description des caractéristiques, des projets de soins et du devenir des patients de plus 75 ans présentant une insuffisance rénale sévère (DFGe ≤ 20 mL/min/1,73 m2) : phase pilote du projet PSPA [Description of characteristics, therapeutic project and outcome of patients older than 75 years with eGFR below 20mL/min/1.73m(2): PSPA pilot study.]. Néphrologie & Thérapeutique, 2012, 8 (7), pp.516-520. ⟨10.1016/j.nephro.2012.03.008⟩. ⟨inserm-00696101⟩
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