Analysis of Cardiac Micro-Acceleration Signals for the Estimation of Systolic and Diastolic Time Intervals in Cardiac Resynchronization Therapy
Résumé
Heart sounds, measured via cardiac micro-acceleration (CMA), carry valuable information about the mechanical and hemodynamic function of the heart. The aim of the present study is to estimate systolic and diastolic time intervals from CMA features, extracted by segmentation of the first two heart sounds, i.e. onset, maximum energy and end instants. CMA, ECG and echocardiographic audio signals were acquired simultaneously on 60 patients under different hemodynamic conditions. Linear models, fitted between CMA features and echo timings, were evaluated with their correlation coefficient, model error and coefficient stability. Models for mitral valve closing, aortic valve closing and opening instants showed satisfactory results, whereas thee stimation of the opening instant of the mitral valve was more difficult. This work suggests the potential utility of CMA for monitoring cardiac function and defining optimal, adaptive pacing configurations.
Mots clés
PEA
ECG
Heart sounds
Cardiac Failure
Cardiac Resynchronization Therapy
time delay
Hemodynamic
Echography
systolic time intervals
diastolic time intervals
electrocardiography
medical signal processing
valves
adaptive pacing configurations
aortic valve closing
cardiac microacceleration signals
echo timings
echocardiographic audio signals
heart sound segmentation
hemodynamic function
mechanical function
mitral valve closing
optimal pacing configurations
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Analysis_of_Cardiac_Micro-Acceleration_Signals_for_the_Estimation_of_Systolic_and_Diastolic_Time_Intervals_in_Cardiac_Resynchronization_Therapy_CinC08.pdf (205.78 Ko)
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