Heterogeneity in head and neck cancer incidence among black populations from Africa, the Caribbean and the USA: Analysis of cancer registry data by the AC3 - Université de Rennes Accéder directement au contenu
Article Dans Une Revue Cancer Epidemiology Année : 2021

Heterogeneity in head and neck cancer incidence among black populations from Africa, the Caribbean and the USA: Analysis of cancer registry data by the AC3

Kellie Alleyne-Mike
  • Fonction : Auteur
Maira Du Plessis
  • Fonction : Auteur
Nkese Felix
  • Fonction : Auteur
Andrew K. Gachii
  • Fonction : Auteur
Robert Hage
  • Fonction : Auteur
Heather-Dawn Lawson-Myers
  • Fonction : Auteur
Theresa Otu
  • Fonction : Auteur
Veronica Roach
  • Fonction : Auteur
Nguundja Uamburu
  • Fonction : Auteur

Résumé

Background: Africa and the Caribbean are projected to have greater increases in Head and neck cancer (HNC) burden in comparison to North America and Europe. The knowledge needed to reinforce prevention in these populations is limited. We compared for the first time, incidence rates of HNC in black populations from African, the Caribbean and USA. Methods: Annual age-standardized incidence rates (IR) and 95% confidence intervals (95%CI) per 100,000 were calculated for 2013-2015 using population-based cancer registry data for 14,911 HNC cases from the Caribbean (Barbados, Guadeloupe, Trinidad and Tobago, N = 443), Africa (Kenya, Nigeria, N = 772) and the United States (SEER, Florida, N = 13,696). We compared rates by sub-sites and sex among countries using data from registries with high quality and completeness. Results: In 2013-2015, compared to other countries, HNC incidence was highest among SEER states (IR: 18.2, 95%CI = 17.6-18.8) among men, and highest in Kenya (IR: 7.5, 95%CI = 6.3-8.7) among women. Nasopharyngeal cancer IR was higher in Kenya for men (IR: 3.1, 95%CI = 2.5-3.7) and women (IR: 1.5, 95% CI = 1.0-1.9). Female oral cavity cancer was also notably higher in Kenya (IR = 3.9, 95%CI = 3.0-4.9). Blacks from SEER states had higher incidence of laryngeal cancer (IR: 5.5, 95%CI = 5.2-5.8) compared to other countries and even Florida blacks (IR: 4.4, 95%CI = 3.9-5.0). Conclusion: We found heterogeneity in IRs for HNC among these diverse black populations; notably, Kenya which had distinctively higher incidence of nasopharyngeal and female oral cavity cancer. Targeted etiological investigations are warranted considering the low consumption of tobacco and alcohol among Kenyan women. Overall, our findings suggest that behavioral and environmental factors are more important determinants of HNC than race.
Fichier principal
Vignette du fichier
Auguste et al-2021-Heterogeneity in head and neck Cancer incidence among black populations from Africa, the Caribbean and the USA Analysis of Cancer registry data by the AC3.pdf (1.14 Mo) Télécharger le fichier
Supplementary materials_AC3 HNC .pdf (1.05 Mo) Télécharger le fichier
Origine : Fichiers produits par l'(les) auteur(s)

Dates et versions

hal-03476826 , version 1 (07-01-2022)

Licence

Paternité - Pas d'utilisation commerciale

Identifiants

Citer

Aviane Auguste, Samuel Gathere, Paulo S. Pinheiro, Clement Adebamowo, Adeola Akintola, et al.. Heterogeneity in head and neck cancer incidence among black populations from Africa, the Caribbean and the USA: Analysis of cancer registry data by the AC3. Cancer Epidemiology, 2021, 75, ⟨10.1016/j.canep.2021.102053⟩. ⟨hal-03476826⟩
75 Consultations
151 Téléchargements

Altmetric

Partager

Gmail Facebook X LinkedIn More