Characteristics of adult patients with chronic intestinal failure due to short bowel syndrome: An international multicenter survey - Université de Rennes Access content directly
Journal Articles Clinical Nutrition ESPEN Year : 2021

Characteristics of adult patients with chronic intestinal failure due to short bowel syndrome: An international multicenter survey

Loris Pironi (1, 2) , Ezra Steiger (3) , Francisca Joly (4) , Palle Jeppesen (5) , Geert Wanten (6) , Anna Sasdelli (1) , Cecile Chambrier (7) , Umberto Aimasso (8) , Manpreet Mundi (9) , Kinga Szczepanek (10) , Amelia Jukes (11) , Miriam Theilla (12) , Marek Kunecki (13) , Joanne Daniels (14) , Mireille Serlie (15) , Florian Poullenot (16) , Sheldon Cooper (17) , Henrik Rasmussen (18) , Charlene Compher (19) , David Seguy (20, 21) , Adriana Crivelli (22) , Lidia Santarpia (23) , Francesco Guglielmi (24) , Nada Rotovnik Kozjek (25) , Stéphane Schneider (26) , Lars Ellegard (27) , Ronan Thibault (2) , Przemysław Matras , Konrad Matysiak , Andrè van Gossum , Alastair Forbes , Nicola Wyer , Marina Taus , Nuria Virgili , Margie O'Callaghan , Brooke Chapman , Emma Osland , Cristina Cuerda , Gábor Udvarhelyi , Lynn Jones , Andre Won Lee , Luisa Masconale , Paolo Orlandoni , Corrado Spaggiari , Marta Bueno Díez , Maryana Doitchinova-Simeonova , Aurora Serralde-Zúñiga , Gabriel Olveira , Zeljko Krznaric , Laszlo Czako , Gintautas Kekstas , Alejandro Sanz-Paris , Mª Estrella Petrina Jáuregui , Ana Zugasti Murillo , Eszter Schafer , Jann Arends , José Suárez-Llanos , Nader Youssef , Giorgia Brillanti , Elena Nardi , Simon Lal , Hector Solar Muñiz , Ruth Hodgson , Siobhan Wallin , Kay Lasenby , Andre Dong Won Lee , Henrik Højgaard Rasmussen , Chrisoffer Brandt , Vanessa Boehm , Julie Bataille , Lore Billiauws , Tomas Molnar , Mihaly Zsilak-Urban , Ferenc Izbéki , Peter Sahin , Anna Simona Sasdelli , Merlo Dario , Valentino Bertasi , Nunzia Regano , Santarpia Lidia , Lucia Alfonsi , Debora Busni , Lyn Gillanders , Anna Zmarzly , Marta Bueno , Carmen Garde , Ma Estrella Petrina Jáuregui , Cora Jonker , Simona Di Caro , Niamh Keane , Pinal Patel , Sarah-Jane Nelson Hughes , Rachel Lloyd , Arun Abraham , Gerda Garside , Michael Taylor , Jian Wu , Trevor Smith , Charlotte Pither , Michael Stroud , Reena Parmar , Nicola Burch , Sarah Zeraschi , Denise Jezerski (3)
Ezra Steiger
  • Function : Author
Florian Poullenot
  • Function : Author
Przemysław Matras
  • Function : Author
Konrad Matysiak
  • Function : Author
Andrè van Gossum
  • Function : Author
Alastair Forbes
  • Function : Author
Nicola Wyer
  • Function : Author
Marina Taus
  • Function : Author
Nuria Virgili
  • Function : Author
Margie O'Callaghan
  • Function : Author
Brooke Chapman
  • Function : Author
Emma Osland
  • Function : Author
Cristina Cuerda
  • Function : Author
Gábor Udvarhelyi
  • Function : Author
Lynn Jones
  • Function : Author
Andre Won Lee
  • Function : Author
Luisa Masconale
  • Function : Author
Paolo Orlandoni
  • Function : Author
Corrado Spaggiari
  • Function : Author
Marta Bueno Díez
  • Function : Author
Maryana Doitchinova-Simeonova
  • Function : Author
Aurora Serralde-Zúñiga
  • Function : Author
Gabriel Olveira
  • Function : Author
Zeljko Krznaric
  • Function : Author
Laszlo Czako
  • Function : Author
Gintautas Kekstas
  • Function : Author
Alejandro Sanz-Paris
  • Function : Author
Mª Estrella Petrina Jáuregui
  • Function : Author
Ana Zugasti Murillo
  • Function : Author
Eszter Schafer
  • Function : Author
Jann Arends
  • Function : Author
José Suárez-Llanos
  • Function : Author
Nader Youssef
  • Function : Author
Giorgia Brillanti
  • Function : Author
Elena Nardi
  • Function : Author
Simon Lal
  • Function : Author
Hector Solar Muñiz
  • Function : Author
Ruth Hodgson
  • Function : Author
Siobhan Wallin
  • Function : Author
Kay Lasenby
  • Function : Author
Andre Dong Won Lee
  • Function : Author
Henrik Højgaard Rasmussen
  • Function : Author
Chrisoffer Brandt
  • Function : Author
Vanessa Boehm
  • Function : Author
Julie Bataille
  • Function : Author
Lore Billiauws
  • Function : Author
Tomas Molnar
  • Function : Author
Mihaly Zsilak-Urban
  • Function : Author
Ferenc Izbéki
  • Function : Author
Peter Sahin
  • Function : Author
Anna Simona Sasdelli
  • Function : Author
Merlo Dario
  • Function : Author
Valentino Bertasi
  • Function : Author
Nunzia Regano
  • Function : Author
Santarpia Lidia
  • Function : Author
Lucia Alfonsi
  • Function : Author
Debora Busni
  • Function : Author
Lyn Gillanders
  • Function : Author
Anna Zmarzly
  • Function : Author
Marta Bueno
  • Function : Author
Carmen Garde
  • Function : Author
Ma Estrella Petrina Jáuregui
  • Function : Author
Cora Jonker
  • Function : Author
Simona Di Caro
  • Function : Author
Niamh Keane
  • Function : Author
Pinal Patel
  • Function : Author
Sarah-Jane Nelson Hughes
  • Function : Author
Rachel Lloyd
  • Function : Author
Arun Abraham
  • Function : Author
Gerda Garside
  • Function : Author
Michael Taylor
  • Function : Author
Jian Wu
  • Function : Author
Trevor Smith
  • Function : Author
Charlotte Pither
  • Function : Author
Michael Stroud
  • Function : Author
Reena Parmar
  • Function : Author
Nicola Burch
  • Function : Author
Sarah Zeraschi
  • Function : Author
Denise Jezerski
  • Function : Author

Abstract

Background and aims: The case-mix of patients with intestinal failure due to short bowel syndrome (SBS-IF) can differ among centres and may also be affected by the timeframe of data collection. Therefore, the ESPEN international multicenter cross-sectional survey was analyzed to compare the characteristics of SBS-IF cohorts collected within the same timeframe in different countries.Methods: The study included 1880 adult SBS-IF patients collected in 2015 by 65 centres from 22 countries. The demographic, nutritional, SBS type (end jejunostomy, SBS-J; jejuno-colic anastomosis, SBS-JC; jejunoileal anastomosis with an intact colon and ileocecal valve, SBS-JIC), underlying disease and intravenous supplementation (IVS) characteristics were analyzed. IVS was classified as fluid and electrolyte alone (FE) or parenteral nutrition admixture (PN). The mean daily IVS volume, calculated on a weekly basis, was categorized as <1, 1-2, 2-3 and >3 L/day.Results: In the entire group: 60.7% were females and SBS-J comprised 60% of cases, while mesenteric ischaemia (MI) and Crohn' disease (CD) were the main underlying diseases. IVS dependency was longer than 3 years in around 50% of cases; IVS was infused ≥5 days/week in 75% and FE in 10% of cases. Within the SBS-IF cohort: CD was twice and thrice more frequent in SBS-J than SBS-JC and SBS-JIC, respectively, while MI was more frequent in SBS-JC and SBS-JIC. Within countries: SBS-J represented 75% or more of patients in UK and Denmark and 50-60% in the other countries, except Poland where SBS-JC prevailed. CD was the main underlying disease in UK, USA, Denmark and The Netherlands, while MI prevailed in France, Italy and Poland.Conclusions: SBS-IF type is primarily determined by the underlying disease, with significant variation between countries. These novel data will be useful for planning and managing both clinical activity and research studies on SBS.
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Dates and versions

hal-03418977 , version 1 (16-10-2023)

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Attribution - NonCommercial

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Loris Pironi, Ezra Steiger, Francisca Joly, Palle Jeppesen, Geert Wanten, et al.. Characteristics of adult patients with chronic intestinal failure due to short bowel syndrome: An international multicenter survey. Clinical Nutrition ESPEN, 2021, 45, pp.433-441. ⟨10.1016/j.clnesp.2021.07.004⟩. ⟨hal-03418977⟩
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